This study wants to compare the immune response in children who received the RSV vaccine during the 2024-2025 respiratory season to those who didn’t. It will also look at how often children in both groups get sick and how severe their sickness is during the 2025-2026 respiratory season.
In this study we want to learn more about how puberty and puberty hormones impact heart health, fitness, and the risk of diabetes in teenagers.
This study wants to see if avacopan is safe and works well for people with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We also want to find out if it helps prevent the disease from coming back.
This study is testing a new injectable medication called anifrolumab to see how safe and effective it is for adults with chronic cutaneous lupus erythematosus (CLE). Our goal is to find better treatments for people living with CLE.
This study is looking at a medicine called Upadacitinib to see if it is safe and helps adults with moderate to severe lupus (SLE). We want to compare it to a placebo (a pill with no medicine) to see how well it works. We also want to find out how much of the medicine is needed to keep symptoms from getting worse.
In this study, we want to compare two methods for treating teens who have substance use disorder (SUD) and symptoms of post-traumatic stress disorder (PTSD). We want to see if Risk Reduction Through Family Therapy (RRFT) or Encompass Treatment is more helpful for treating teens with these mental health problems.
This study wants to learn more about CXA-10, a naturally occurring compound in the body. Researchers will test whether CXA-10 is safe and if it helps people who have asthma and are also living with obesity.
This study will test a new medicine called DMX-200 to see if it can lower protein in the urine and slow kidney damage in people with focal segmental glomerulosclerosis (FSGS) who are already taking an ARB medicine. Researchers will also look at how safe DMX-200 is, how well people can handle it, how it affects kidney health and quality of life, and how the body uses the medicine.
In this study we want to learn more about the effects of the study drug, benralizumab, for treating children with eosinophilic granulomatosis with polyangiitis (EGPA).
The main goal of this study is to see if using a Fitbit and getting helpful text messages can support people with type 2 diabetes in taking better care of their health. The study will check if the 12-week program is easy to use and useful for patients.
This study plans to learn more about how a telehealth exercise program designed for rural survivors of cancer can help improve cancer related fatigue.
This study wants to learn if taking a protein supplement drink twice a day for 8 weeks can help lower the amount of fat that is stored in the liver.
We want to learn more about the diseases that cause nephrotic syndrome. This is a group of symptoms that happen when the kidneys don't work the right way. We will collect health information and lab samples to help us discover new things. We hope this will help doctors, researchers, and the public.
The purpose of this research is to evaluate the study drug, pemvidutide, as a possible treatment for alcohol use disorder (AUD). This research will help to answer the question of whether pemvidutide could be helpful as a treatment for people who are trying to reduce or quit their drinking of alcohol. This research will also help to answer the question of whether pemvidutide could be helpful in red...
This study wants to learn more about the heart and brain health of people with and without endometriosis.
We want to find out how well the medicine Belimumab works in real life for adults who have active lupus nephritis. This study also wants to see if belimumab helps keep the kidneys healthy for a long time.
This study wants to learn more about how estrogen affects women's reproductive hormones and system.
We want to learn if ravulizumab can help slow down or stop kidney problems and lower protein in the urine. We will also compare ravulizumab to a placebo (a substance with no medicine) to see how well it works.
Do you currently smoke? Would you like to know if you are one of the 4 in 10 people who may develop COPD someday?
This study is testing a new drug called SC291 to see if it is safe and if it can help treat serious autoimmune diseases that have come back or stopped responding to treatment.
This study wants to learn more about how blood sugar levels in healthy children without chronic disease compare to the blood sugar levels of children with Cystic Fibrosis (CF). We are only recruiting children without chronic disease to join the study.
This study wants to find better treatments for people with autoimmune diseases like rheumatoid arthritis (RA). By studying the different types of cells found in people with RA, researchers can learn more about how RA damages joints.
This research study is being conducted to examine the effects of dapagliflozin on kidney function, blood vessel function and heart function. We are studying the effects/impact of dapagliflozin (a SGLT2 inhibitor) on: - Kidney function - Protein in the urine - Blood vessel function - Heart function
This study wants to know if a new drug called Diamyd®, can safely and effectively treat type 1 diabetes.
In this study, we want to learn more about a new drug called iptacopan to see if it can help treat a rare kidney disease called IC-MPGN (immune complex mediated membranoproliferative glomerulonephritis).
This study wants to learn more about how the right side of the heart works in people with chronic obstructive pulmonary disease (COPD). We want to see how the heart responds to high blood pressure in the lungs, both while resting and during exercise. The goal is to find patterns that could lead to better treatments for people with COPD.
In this study we want to gather more information about the safety and tolerability of a drug called ferric citrate for treating children with chronic kidney disease who have hyperphosphatemia.
Although non-small cell lung cancer (NSCLC) patients with anaplastic lymphoma kinase (ALK), c-ros oncogene 1(ROS1), and ret proto-oncogene (RET) gene fusions initially respond well to tyrosine kinase inhibitor (TKI) therapies, acquired resistance is inevitable. In many of these cases, increased activation of the erythroblastic leukemia viral oncogene homologue (ERBB) or cMet pathways appears to be...
We want to find better ways to treat bipolar disorders. We are looking for children, teens, and young adults, aged 9 to 21 years old, to join our study.
This study wants to learn new ways to prevent and respond to pandemics by studying current infections, like colds. We will collect and store biological samples and health data from children to use in research to make drugs, tests, and vaccines for these types of infections.
This study is for women who are about to start IVF. It will test if the medicine, Orilissa, which helps with endometriosis symptoms, will affect fertility.
This study wants to learn more about hearing loss using samples from a child, both of their biological parents, and/or other family members. We will use the samples to study heritable risk factors for hearing loss and changes in gene expression that lead to hearing loss and/or ear abnormalities.
In this study we want to learn if a medicine approved for diabetes and weight loss called Ozempic® and Wegovy® (semaglutide) can help improve the frequency of periods and the way the body uses sugar in women with polycystic ovary syndrome (PCOS).