This study wants to learn more about CXA-10, a naturally occurring compound in the body. Researchers will test whether CXA-10 is safe and if it helps people who have asthma and are also living with obesity.
This study will test a new medicine called DMX-200 to see if it can lower protein in the urine and slow kidney damage in people with focal segmental glomerulosclerosis (FSGS) who are already taking an ARB medicine. Researchers will also look at how safe DMX-200 is, how well people can handle it, how it affects kidney health and quality of life, and how the body uses the medicine.
In this study we want to learn more about the effects of the study drug, benralizumab, for treating children with eosinophilic granulomatosis with polyangiitis (EGPA).
The main goal of this study is to see if using a Fitbit and getting helpful text messages can support people with type 2 diabetes in taking better care of their health. The study will check if the 12-week program is easy to use and useful for patients.
This study plans to learn more about how a telehealth exercise program designed for rural survivors of cancer can help improve cancer related fatigue.
This study wants to learn if taking a protein supplement drink twice a day for 8 weeks can help lower the amount of fat that is stored in the liver.
We want to learn more about the diseases that cause nephrotic syndrome. This is a group of symptoms that happen when the kidneys don't work the right way. We will collect health information and lab samples to help us discover new things. We hope this will help doctors, researchers, and the public.
The purpose of this research is to evaluate the study drug, pemvidutide, as a possible treatment for alcohol use disorder (AUD). This research will help to answer the question of whether pemvidutide could be helpful as a treatment for people who are trying to reduce or quit their drinking of alcohol. This research will also help to answer the question of whether pemvidutide could be helpful in red...
This study wants to learn more about the heart and brain health of people with and without endometriosis.
We want to find out how well the medicine Belimumab works in real life for adults who have active lupus nephritis. This study also wants to see if belimumab helps keep the kidneys healthy for a long time.
This study wants to learn more about how estrogen affects women's reproductive hormones and system.
We want to learn if ravulizumab can help slow down or stop kidney problems and lower protein in the urine. We will also compare ravulizumab to a placebo (a substance with no medicine) to see how well it works.
Do you currently smoke? Would you like to know if you are one of the 4 in 10 people who may develop COPD someday?
This study is testing a new drug called SC291 to see if it is safe and if it can help treat serious autoimmune diseases that have come back or stopped responding to treatment.
This study wants to learn more about how blood sugar levels in healthy children without chronic disease compare to the blood sugar levels of children with Cystic Fibrosis (CF). We are only recruiting children without chronic disease to join the study.
This study will test the Home Health Box in real homes by having people measure and track the air quality in their home, see how easy it is to use based on their feedback, and make improvements before bringing the device to market.
This study wants to find better treatments for people with autoimmune diseases like rheumatoid arthritis (RA). By studying the different types of cells found in people with RA, researchers can learn more about how RA damages joints.
This research study is being conducted to examine the effects of dapagliflozin on kidney function, blood vessel function and heart function. We are studying the effects/impact of dapagliflozin (a SGLT2 inhibitor) on: - Kidney function - Protein in the urine - Blood vessel function - Heart function
This study wants to know if a new drug called Diamyd®, can safely and effectively treat type 1 diabetes.
In this study, we want to learn more about a new drug called iptacopan to see if it can help treat a rare kidney disease called IC-MPGN (immune complex mediated membranoproliferative glomerulonephritis).
This study wants to learn more about how the right side of the heart works in people with chronic obstructive pulmonary disease (COPD). We want to see how the heart responds to high blood pressure in the lungs, both while resting and during exercise. The goal is to find patterns that could lead to better treatments for people with COPD.
In this study we want to gather more information about the safety and tolerability of a drug called ferric citrate for treating children with chronic kidney disease who have hyperphosphatemia.
Although non-small cell lung cancer (NSCLC) patients with anaplastic lymphoma kinase (ALK), c-ros oncogene 1(ROS1), and ret proto-oncogene (RET) gene fusions initially respond well to tyrosine kinase inhibitor (TKI) therapies, acquired resistance is inevitable. In many of these cases, increased activation of the erythroblastic leukemia viral oncogene homologue (ERBB) or cMet pathways appears to be...
We want to find better ways to treat bipolar disorders. We are looking for children, teens, and young adults, aged 9 to 21 years old, to join our study.
This study seeks to better understand the effects of cannabis use during adolescence on decision making and reward responsivity and may identify biomarkers that help distinguish youth who experience impairments in decision making and are at higher risk of the negative effects of cannabis use.
This study wants to learn new ways to prevent and respond to pandemics by studying current infections, like colds. We will collect and store biological samples and health data from children to use in research to make drugs, tests, and vaccines for these types of infections.
This study is for women who are about to start IVF. It will test if the medicine, Orilissa, which helps with endometriosis symptoms, will affect fertility.
This study wants to learn more about hearing loss using samples from a child, both of their biological parents, and/or other family members. We will use the samples to study heritable risk factors for hearing loss and changes in gene expression that lead to hearing loss and/or ear abnormalities.
In this study we want to learn if a medicine approved for diabetes and weight loss called Ozempic® and Wegovy® (semaglutide) can help improve the frequency of periods and the way the body uses sugar in women with polycystic ovary syndrome (PCOS).
This study wants to learn about the best way to take pictures of unborn babies' hearts to better identify certain heart health problems.
This study plans to learn how the physical, mental, and emotional well-being of adolescents who do or do not play sports or participate in other activities change over the course of a fall school semester (10-13 weeks).
To measure the compensatory reserve volume of pregnant women undergoing cesarean section.