Efficacy and mechanisms of dapagliflozin in promoting kidney function and cardiovascular health in kidney transplant recipients
This research study is being conducted to examine the effects of dapagliflozin on kidney function, blood vessel function and heart function. We are studying the effects/impact of dapagliflozin (a SGLT2 inhibitor) on: - Kidney function - Protein in th
Why this Research Matters
Main procedures done in the study: - Physical exam and medical history - Blood draw - Blood pressure - Blood vessel function testing - Urine collection - Kidney function measures - Kidney and cardiac MRI You will take study drug daily for 12 mont
Who can Participate
- History of kidney transplant - History of diabetes type 2 or posttransplant diabetes mellitus We need men and women who are: - Age 18 years and older - History of kidney transplant - History of diabetes type 2 or posttransplant diabetes mellitus - Women must not be pregnant or breastfeeding - Urine albumin to creatinine ratio of 30-5000 mg/g
Study ID
Protocol Number: 23-1360
Meet the Team
Principal Investigator