The study is being conducted in participants with an autoimmune disease, specifically systemic lupus erythematosus (SLE), idiopathic inflammatory myopathy (IIM), or systemic sclerosis (SSc). The goal is to test if study drug, ALLO-329 CAR T cells can safely reset the immune system and achieve lasting remission of these diseases.
This study is being done to learn more about anifrolumab in patients with idiopathic inflammatory myopathies (IIM), which includes disease subtypes of polymyositis (PM) and dermatomyositis (DM) and also to better understand the studied disease and associated health problems.
The study is evaluating the study drug and looking at how well it works, how it is tolerated and how safe it is for people with primary Sjogren's disease (pSjD).
This study wants to learn more about spondyloarthritis, a type of arthritis that causes a lot of inflammation. We are looking for adults who have a parent, sibling, or child who has spondyloarthritis or a similar health problem to join our study.
This study is looking at how well a new drug called GS-5718 works for people with Cutaneous Lupus Erythematosus (CLE), with or without systemic lupus. We want to see if it helps reduce rashes and sores and if people can take it without a lot of side effects.
This study is testing a new treatment called CAR T cell therapy to see if it’s safe and works well for people with rheumatoid arthritis (RA). It uses a person’s own immune cells to help fight disease. In this study, a type of cell called regulatory T cells (Tregs) will be genetically modified into CAR Tregs (called SBT777101) to see if they are better at reducing inflammation in people with RA.
This study wants to see if avacopan is safe and works well for people with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We also want to find out if it helps prevent the disease from coming back.
This study is testing a new injectable medication called anifrolumab to see how safe and effective it is for adults with chronic cutaneous lupus erythematosus (CLE). Our goal is to find better treatments for people living with CLE.
In this study we want to learn more about the effects of the study drug, benralizumab, for treating children with eosinophilic granulomatosis with polyangiitis (EGPA).
This study will test if adding a new medicine called VIB4920 to regular lupus treatment can help people with lupus nephritis (a kidney problem caused by lupus) feel better. It will also check if this new medicine is safe.
We want to find out how well the medicine Belimumab works in real life for adults who have active lupus nephritis. This study also wants to see if belimumab helps keep the kidneys healthy for a long time.
We are looking for adults to join a national study to help us learn more about how rheumatoid arthritis (RA) develops.
This study wants to find better treatments for people with autoimmune diseases like rheumatoid arthritis (RA). By studying the different types of cells found in people with RA, researchers can learn more about how RA damages joints.