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An Open_label, Randomized Controlled Trial of Pramipexole versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD with Mild Neurocognitive Disorder (MND) in Persons with HIV

To compare pramipexole to escitalopram in the treatment of major depressive disorder in people living with HIV.


Why this Research Matters

The purpose of this research study is to evaluate the safety and efficacy of pramipexole extended release (ER) versus escitalopram for the treatment of major depressive disorder (MDD) and mild neurocognitive disorder (MND) in people living with HIV (PWH).


Who can Participate

Adult

Individuals living with HIV and with a diagnosis of major depressive disorder


Study ID

Protocol Number: 24-2084

Meet the Team

Image of Principal Investigator

Thomas Campbell, MD

Principal Investigator