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The main goal of this study is to learn whether CNP-103 is safe and well tolerated in teenagers and young adults with recently diagnosed type 1 diabetes. We will look at how people react to CNP-103 compared to a placebo which looks like the study drug but has no active medicine.

We want to understand how physical activity and bone health are related in female youth. For one year, we will look at physical activity and bone health in active teenagers without an eating disorder and teenagers who are getting care for a restrictive eating disorder.

To evaluate the efficacy of ALK-001 compared with placebo in slowing the progression of retinal atrophic lesion growth in participants with STGD

This study is testing a new drug called baricitinib in children and young adults who have recently been diagnosed with type 1 diabetes (T1D). We want to learn whether it can help preserve beta cells and slow the progression of T1D.

Primary Objective To assess efficacy of intravenous (IV) brincidofovir (BCV), compared with IV cidofovir (CDV), in subjects after allo-HCT with adenovirus (AdV) viremia. Secondary Objectives To assess the safety of IV BCV, compared with IV CDV, in subjects after allo-HCT with AdV viremia. To assess IV BCV pharmacokinetics (PK).

This study wants to find out how physical activity affects bone strength in teens with and without cerebral palsy (CP).

In this study we want to learn how babies are affected when their mothers have a viral infection during pregnancy. To do this, we will collect blood samples from pregnant women who have viral infections (like COVID-19) and those who do not.

This study wants to learn how treating Hepatitis C during pregnancy affects the health of pregnant women and their babies.

In this study we are testing a new drug called teplizumab to see if it can help protect the cells that make insulin in people with type 1 diabetes. We want to know if it can improve blood sugar levels, reduce the need for extra insulin, and lower the risk of low blood sugar.

This study will look at whether getting a second dose of RSVpreF (Abrysvo®) vaccine during another pregnancy is safe and can help your body make antibodies that may protect your baby from Respiratory Syncytial Virus (RSV). We will also check to see if you still have antibodies from the dose you got during your previous pregnancy.

This is a Phase 1/2, open-label study designed to evaluate the safety and efficacy of CABA-201 in patients with active IIM or JIIM and to identify an appropriate dose for future studies.

This registry wants to learn whether taking Vumerity (Diroximel Fumarate) during pregnancy impacts the health of pregnant women with MS or their babies. We will compare the health of women who took Vumerity during pregnancy with the health of women who took other MS medicines or no MS medicine during pregnancy.

In this study, we want to learn more about inflammation and the immune system in people with Down syndrome. We are testing whether a study drug called tofacitinib can help lower inflammation and improve health and development in children and young adults with Down syndrome.

We are studying how a type of chemotherapy called doxorubicin affects the heart and arteries. We are looking for lymphoma survivors and healthy adults to join this study.

This study looks at how choline supplements and exposure to cannabis-based products affect pregnancy and child health.

In this study, we want to learn if eating meals together as a family can help improve your child’s health, and the health of other family members too!

In this study, we want to better understand how the environment and things that happen early in children’s lives—even before they are born—affect their development, health, and well-being.

This study wants to learn more about how exposures during pregnancy like infections, diet and growth, can affect a baby’s chances of developing type 1 diabetes later in life.

We want to find better ways to treat bipolar disorders. We are looking for children, teens, and young adults, aged 9 to 21 years old, to join our study.

This study will collect data from health records about people that have variations in their X & Y chromosomes to learn about their health. We also ask if people are willing to join future studies about X & Y variations.

We are looking for couples that have had two or more pregnancy losses with no known cause. We want to find out if genetics might be a reason for recurrent pregnancy loss (RPL).

This study wants to learn more about how COVID-19 and diabetes are connected.

This study wants to collect medical information from people with Turner Syndrome at clinics across the country to learn more about the condition. We are gathering this data in a national registry to help improve the health and care for people with Turner Syndrome in the future.

This study wants to learn how a type of fat in the blood, called triglycerides, affects how the fetus grows.

This study wants to find a new combination of drugs that is safe and effective to treat people who have bone cancer that has come back or not responded to other treatments.

In this study, we want to learn about the effects of physical activity on the health of teenagers. We will compare the physical, mental, and emotional health of teens who take part in physical activities with those who do not during a fall semester (10–14 weeks).

This study wants to better understand Down syndrome and related health problems by comparing blood and saliva samples from people with and without Down syndrome. Right now, we are mainly looking for people who do not have Down syndrome but do have chronic constipation to join our study.

In this study we want to find out how the body’s immune system reacts to nuts and other foods and causes allergies. We also want to check how well a new test works that may help predict allergic reactions to peanuts

The purpose of this study is to learn if improving sleep habits and sleep timing can help improve blood sugar and heart health in teens who do not get enough sleep.

This study will look at whether a one-time session can help you prepare for delivery, reduce concerns about giving birth, and improve perinatal mood, anxiety, and trauma symptoms (PMATS).

The goal of this study is to learn more about inflammation and how well the kidneys and blood vessels work in young adults with type 2 diabetes (T2D).

This intervention development and proof-of-concept study addresses the need for a developmentally tailored, flexible intervention that targets risk factors and features of children with SITBs. We will systematically and iteratively adapt and combine existing EBIs for children targeting emotion dysregulation and executive functioning for SITBs and evaluate feasibility and safety of SURE-Kids, as we...

In this study we want to compare how well two different drugs work to treat kids and young adults that have a narrow or stiff esophagus because of a health problem called eosinophilic esophagitis.

In this study we want to learn about how safe and how well a treatment called Fetoscopic Endoluminal Tracheal Occlusion works to treat babies that have a condition called right and left Congenital Diaphragmatic Hernia.

In this study we are testing how two drugs, Thymoglobulin ® and verapamil, work together to treat children and young adults with newly diagnosed type 1 diabetes.

In this study we want to collect baseline data on how well treatment works for kids and adults with pulmonary arteriovenous malformations.

In this study we want to learn how a device that automates insulin delivery (called the iLet Bionic Pancreas) helps people with Cystic Fibrosis Related Diabetes manage their insulin levels. We want to learn how well this device works compared to a normal insulin delivery method.

In this study, we want to learn whether adding a new oral drug called Venetoclax to standard chemotherapy affects how long children and young adults with acute myeloid leukemia (AML) stay in remission and what side effects they experience.

This study wants to see if a new drug called SAB-142 in addition to regular insulin therapy can help slow down Type 1 Diabetes (T1D) in people who were diagnosed in the last 100 days.

In this study, we want to learn how teens handle stress, deal with feelings of depression, and manage habits like eating, exercise, and sleep. We will use what we learn to make a Digital App that helps teens struggling with these challenges.

In this study we want to learn more about how common health problems like high blood pressure, vision problems, and kidney disease are in people with cystic fibrosis-related diabetes (CFRD).

In this study we want to see if improving the amount and quality of sleep will help improve the overall health of adolescents that have type 1 diabetes (TID).

In this study we want to determine the best intervention for improving sleep quality in people recovering from a concussion. To do this we are comparing two sleep interventions and seeing how the impact the recovery time for a concussion.

In this study we want to learn more about a new treatment called CD19x22 CAR T cells. We want to see how well it works as a treatment for B-cell Acute Lymphoblastic Leukemia (B-ALL) when the cancer has come back after treatment or hasn’t responded to previous treatments.

In this study we want to learn more about achondroplasia and the genetic factors and health outcomes linked to it. To do this, we are collecting DNA (from saliva samples) from people who have achondroplasia and their family members.

This study wants to learn if taking a protein supplement drink twice a day for 8 weeks can help lower the amount of fat that is stored in the liver.

In this study, we want to see if two anti-rejection drugs (belatacept and sirolimus) can better protect your new kidney after kidney transplant, compared to the currently used drugs (tacrolimus and MMF).

In this study, we want to learn more about a new drug called iptacopan to see if it can help treat a rare kidney disease called IC-MPGN (immune complex mediated membranoproliferative glomerulonephritis).

In this study we want to learn if a medicine approved for diabetes and weight loss called Ozempic® and Wegovy® (semaglutide) can help improve the frequency of periods and the way the body uses sugar in women with polycystic ovary syndrome (PCOS).

Our team is here to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or combination of therapy and exercise training lowers stress, improves mood, raises physical activity and fitness, and lowers diabetes risk among teen girls at risk for diabetes.