Your search for "Healthy Volunteers" found 65 matches:
Solid foods and infant growth

Your baby may be eligible if they are: - Exclusively breastfed - Younger than six months of age - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every month. The first visit, 9-month visit, an...

Protocol #: 19-0546

Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Women Compared to Age Group-Matched Cisgender Adults

Do you qualify? • Transgender women (i.e., assigned male at birth but identify as female) taking estradiol and spironolactone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o...

Protocol #: 18-2258

Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Men Compared to Age Group-Matched Transgender Women and Cisgender Adults

Transgender men (i.e., assigned female at birth but identify as male) taking testosterone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o No history of cancer, diabetes or heart d...

Protocol #: 19-2323

Microfluidic models of bleeding and thrombosis

This study plans to learn more about how blood composition affects the formation of blood clots and to identify how individuals respond to commons drugs like anticoagulants and hormone treatments. ...

Protocol #: 19-2408

Birth Control Hormonal Injection/Shot Study

-36 visits over 9 months -Physical Exam, Pelvic Exam-On screening Visit and Exit visit only -Trans-Vaginal Ultrasound, Blood draws-On every visit -Bleeding Diaries-will be filled collected weekly after Visit 3...

Protocol #: 19-2820

Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex

Participants will undergo baseline testing of heart and blood vessel function as well as skeletal muscle function and exercise ability. Participants will then do cardiovascular exercise for 15 weeks, and all testing will be repeated....

Protocol #: 17-0356

Evaluation of Intestinal Permeability and Chronic Inflammation in Patients with Type 2 Diabetes and Obesity Compared to Healthy Lean Controls (IDOS)

Participants will complete 2-3 visits- a screening visit and a testing visit. Some participants will be asked to split screening into 2 visits. All visits include blood draws and the testing visit includes blood draws and frequent urine samples. Participants will also be asked to provide a...

Protocol #: 20-2179

Effects of complementary feeding on infant growth and gut health

Your baby may be eligible if they are: - Breastfed and/or formula fed - Younger than five months of age - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a seven month-long study, from 5 to 12 months of age, with visits occurring every month. ...

Protocol #: 20-2232

The impact of estrogen status on the biological function of brown adipose tissue in women measured using quantitative PET/CT

The physiological relevance of brown adipose tissue in humans is largely unknown. We have shown that suppressing ovarian function in premenopausal women reduces resting energy expenditure (REE), and this is prevented by adding back estradiol (E2). Our preliminary data suggest that this may...

Protocol #: 16-1479

Blueberry intake and infant gut health

Your breastfed baby may be eligible if they are: - Younger than six months of age - Exclusively breastfed - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every other month. The first and last ...

Protocol #: 20-1659

Early iron exposure on the gut microbiota in young infants

This is a four month-long study, beginning at birth. The first study visit is conducted at the University of Colorado Hospital and the last visit takes place at Children’s Hospital Colorado. The other four visits are conducted in your home. Formula is provided to all study participants for...

Protocol #: 18-1317

Colorado Pulmonary Alcohol Research Consortium

We are looking for volunteers to serve as control subjects to be compared to people who drink heavily in a research project that examines substances collected from inside the lungs....

Protocol #: 12-0181

Location: CTRC-adult, University of Colorado Hospital

REACH - Role of microvascular insulin resistance and cardiorespiratory fitness in diabetes

Participants will undergo baseline testing of heart and blood vessel function as well as skeletal muscle function and exercise ability. Participants will then do cardiovascular exercise for 15 weeks, and all testing will be repeated....

Protocol #: 20-2723

Research about the Potential for the Contraceptive Implant as Emergency Contraception

Are you a healthy female between the ages of 18-40? Are you interested in starting Nexplanon®, hormonal birth control that goes in your arm? Are you interested in how your body works, specifically in regard to ovulation? This study is determining if when placing an etonogestrel implant ...

Protocol #: 21-5026

Prolonged Sedentary Behavior in Older Women with and without Type 2 Diabetes: Knowledge, Engagement, and Relationship to Cardiometabolic Risk

Are you interested in participating in a research study to understand the health effects of the time we spend sitting? The ACTIVE Research Lab is looking for: • Women • 60 to 75 years of age • Non-smoker • If Type 2 Diabetes, not being treated with insulin • BMI 25-40 kg/m2 (check ...

Protocol #: 19-2758

SHINGLES VACCINE RESEARCH STUDY PERSONS AGE 50 AND OLDER

We are recruiting for 2 groups; you may be eligible to participate if you are • Age 50 or older • In general good health, and • Have never had shingles, and * Received a shingles vaccine = 5 years ago and can provide documen...

Protocol #: 18-0580

Location: CU Anschutz non-hospital research facilities

Premature Vascular Aging in Women following an In Vitro Fertilization Pregnancy

Ultrasound of blood vessels, blood draw, 24-hour blood pressure monitoring, body composition and bone mineral density testing Compensation is provided....

Protocol #: 21-2903

Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics

Inclusion criteria: - Women aged 18-55 years - Non-smoking - Not taking medications to treat high blood pressure or cholesterol ...

Protocol #: 21-3590

NightWare Therapeutic Platform for improving Cardiovascular Health in Adults With Nightmares Associated with PTSD

We are recruiting individuals who experience PTSD-associated nightmares to participate in a research study to help us understand if improving sleep quality, by reducing the impact of nightmares can improve cardiovascular health....

Protocol #: 21-5027

Skeletal Response to Simulated Night Shift (SPOTLIGHT Study)

What is involved: • Measurements of bone mineral density • Completion of sleep questionnaires/assessments • Randomization to sleep with a simulated night shift schedule or normal sleep schedule • A general physical exam • Activity monitoring with a wrist monitor • Blood/urine collec...

Protocol #: 20-3013

Contraceptive Hormone and Reward Measurement (CHARM Study)

Protocol #: 21-3530

Social Information Processing in Teens (SIP Study)

Interested in how irritability affects social information processing in teens? Our goal is to learn more about how people commonly react to social ambiguity and how irritable mood may relate to negative interpretations of social signals in adolescence....

Protocol #: 20-2633

Molecular Transducers of Physical Activity Consortium (MoTrPAC) - Adult

The purpose of MoTrPAC is to learn about how exercise benefits health. We know that being physically active is good for our health, but we don’t completely understand how it changes the cells in our bodies. Understanding the cellular benefits of exercise could help scientists develop new...

Protocol #: 18-0220

The short-chain fatty acid acetate for improving age-associated arterial dysfunction

Specific Aim: To determine the following before and after 12 weeks of oral supplementation with calcium acetate vs. placebo (calcium citrate) in healthy men and women 50+ years of age: a) Endothelium-dependent dilation, assessed as brachial artery flow-mediated dilation (FMDBA) [primary o...

Protocol #: 22-0473

Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty

This research studies how hormones impact headache and how different parts of the brain talk to each other. You are invited to participate if you are (or your child is): • 11 years to 20 years of age • With or without history of headache • Male sex, male gender identity • Healt...

Protocol #: 20-1824

MitoQ supplementation for restoring aerobic exercise training effects on endothelial function in postmenopausal women

Protocol #: 22-1521

The Influence of Combined Oral Contraceptives on Weight: A 6-Month Observational Study

**Now only recruiting women interested in starting the Sprintec oral contraceptive pill and willing to remain on it for the 6-month duration of this study** Approximately 15 million women of reproductive age women in the United States have overweight or obesity and use the combined estr...

Protocol #: 21-3969

Location: CTRC-adult, UCHealth-Metro Denver

Understanding Maternal Stress and Feeding Practices among Mothers of Infants Transitioning to Solid Foods

This study plans to learn more about how mothers’ stress is related to how they feed their infants and toddlers. We know that stress can affect how we feed very young infants, but we do not fully understand the ways stress might affect how we feed our older infants and toddlers as they tra...

Protocol #: 22-0382

Location: CU Anschutz non-hospital research facilities

Physical Activity and Autosomal Dominant Polycystic Kidney Disease

This research study is being conducted to learn more about physical activity habits in those with ADPKD....

Protocol #: 22-0072

Location: Renal Research Center

Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer (ORIEN)

Protocol #: 15-1110

Location: Cherry Creek Medical Center, Memorial Hospital Central, Memorial Hospital North, Poudre Valley Hospital, University of Colorado Hospital

Real-Time Assessment of Lung Structure and Function in Children and Young Adults with CF using Electrical Impedance Tomography

Single visit to Children's Hospital Colorado - During this visit your height, weight, date of birth, and gender will be recorded. You will also have some tests done including pulmonary function testing (spirometry), EIT, and multiple breath washout (MBW)....

Protocol #: 22-0114

Location: Childrens Hospital Colorado

A double-blind, placebo-controlled crossover study comparing the analgesic efficacy of cannabis versus oxycodone

Protocol #: 14-1909

Location: CTRC-adult, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Is disruption of the human gut microbial environment associated with cognitive impairment following chemotherapy for breast cancer?

Protocol #: 16-2138

Location: University of Colorado Hospital

Cardiovascular consequences of hypogonadism in men

Protocol #: 15-1162

Location: Outpatient CTRC, Rocky Mountain Regional VA Medical Center, University of Colorado Hospital

Effect of Mechanical Circulatory Support on Exercise Capacity in Heart Failure

Protocol #: 16-1635

Location: Colorado Research Center, CTRC-adult, Outpatient CTRC, University of Colorado Hospital

Comparing WatchPAT to Polysomnography in the Assessment of Sleep Disordered Breathing in At-Risk Adolescents

Participants will wear the WatchPAT device during their PSG appointment and the results between the two tests will be compared....

Protocol #: 22-0847

Location: Childrens Hospital Colorado

Human Trisome Project

Additional information about this study can be found at www.trisome.org....

Protocol #: 15-2170

Location: Childrens Hospital Colorado, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Rapid measurements of water isotopes in human breath and saliva for doubly labeled water analysis V: 04/03/18

Protocol #: 16-2203

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Improving our knowledge about maternal behavior and its potential effect on infant outcomes

Protocol #: 17-2033

Location: CU John C. Hobbins Perinatal Center, CU Parker Perinatal Center, Denver Health and Hospital Authority, Department Specific Free Standing Clinic, University of Colorado Hospital

EA1151: Tomosynthesis Mammographic Imaging Screening Trial (TMIST)

Participants in this trial will be randomized to receive either 2D or 3D mammograms for the first 5 years of the research study, either ever year or every other year depending on personal risk factors. Information will be collected on breast cancer status for 8 years in total. ...

Protocol #: 18-0392

Location: Highlands Ranch Hospital, Outpatient CTRC, University of Colorado Hospital

Defining Molecular Phenotypes of Exacerbation-Prone Asthmatics (ENIGMA)

We want to learn more about asthma and how stuff in the air, like pollution and allergens, can make asthma worse in children. To do this we want to look at kids with and without asthma. If you join the study, you will participate in a remote consent visit, a clinic visit and a remote home...

Protocol #: 17-1416

Location: Childrens Hospital Colorado

PLACENTAL PROTEINS AND PREMATURITY (P3 STUDY)

This study plans to learn more about why babies born prematurely sometimes can have problems with infections, breathing, feeding, vision, and brain function....

Protocol #: 18-0637

Location: Outpatient CTRC, University of Colorado Hospital

Identifying Environmental Triggers of Smoking Behaviors in Low-income Communities

Protocol #: 18-0052

Location: Department Specific Free Standing Clinic, University of Colorado Cancer Center, University of Colorado Hospital

Identifying Predictors of Poor Health-Related Quality-of-Life among Pediatric Hematopoietic Stem Cell Donors

Protocol #: 18-1997

Location: Childrens Hospital Colorado

The Associations between EIT and Clinical Measures during Standard of Care Procedures in Patients with Respiratory Disease: A Preliminary Study

Protocol #: 18-1843

Location: Childrens Hospital Colorado

CU Faces of Hope-Genetics of Craniofacial and Dental Development Research Study

This study plans to collect samples to create a database of patients with various syndromes that affect the way bones of the face are formed, termed “craniofacial”. These samples will support a new research program, named CU Faces of Hope, which involves a team of researchers and doctors ...

Protocol #: 18-1916

Location: Childrens Hospital Colorado

Bioenergetic and Metabolic Consequences of the Loss of Gonadal Function- 2018

This research study is investigating the roles of estrogen (female sex hormone) and FSH, or follicle-stimulating hormone, on cortisol (a stress hormone), fat gain, and disease risk....

Protocol #: 18-2483

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Multiomics Investigation of Marijuana Use

This research study seeks to learn more about biomarkers and biological pathways associated with marijuana use. We are enrolling adults who are marijuana users or non-users. The study involves filling out online surveys and one on-campus visit to give a blood, urine, and hair sample. If yo...

Protocol #: 18-0853

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Cardiopulmonary and Right Ventricular Function in Health and Disease

The primary objective of this research protocol is to advance the understanding of cardiopulmonary and right ventricular (RV) performance among individuals with cardiomyopathy (heart failure with reduced ejection fraction [HFrEF], heart failure with preserved ejection fraction [HFpEF]), as...

Protocol #: 19-1141

Location: Brain Imaging Center - BIC, CTRC Inpatient, University of Colorado Hospital

Sex-based differences in the neuronal mechanisms of food intake behavior

Participants will: -Complete 2 to 4 MRI scans -Complete food, attention, and mood questionnaires -Complete blood draws for measuring hormones -Receive a free Fitbit...

Protocol #: 19-1148

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

The Neural Underpinnings of Disinhibited Eating Behavior in Adolescents with and without Obesity

Protocol #: 19-1171

Location: Brain Imaging Center - BIC, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Allen CU-UCSD Transition to RA Project: Blood and Flu

Protocol #: 19-1150

Location: Barbara Davis Center, University of Colorado Hospital

Gait Analysis of Femoroacetabular Impingement Patients

Protocol #: 16-1934

Location: Childrens Hospital Colorado

Effects of puberty and pubertal suppression on insulin sensitivity, metabolic rate and vascular health

This study will involve 4-5 in person visits. There will be screening visit for some patients and then a baseline visit over two days. The first day will involve an IV and drinking a sugary drink with blood draws as well as measuring the resting metabolic rate and answering questionnaires....

Protocol #: 19-2109

Location: Childrens Hospital Colorado, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Validation of the Apollo EE Device, Indirect Calorimetry

Protocol #: 20-0317

Location: Anschutz Health and Wellness, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18 Years and Older (mRNA-1273-P301)

Protocol #: 20-1619

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth (PUBERTY)

This study will involve 6 research visits at 3 timepoints for transgender individuals (before starting estrogen and 6 and 12 months after starting estrogen). No medications are given as a part of this study. Cisgender (non-transgender) participants will have 4 visits at two timepoints ...

Protocol #: 19-1226

Location: Childrens Hospital Colorado, University of Colorado Hospital

Disordered Eating, Energy Availability, and Quality of Life in Adolescent Athletes

Participants will receive a DEXA scan and will wear a FitBit for a week to track HR, sleep, and exercise. The participant will also log their food intake for the week. Compensation included. ...

Protocol #: 20-1681

Location: Childrens Hospital Colorado, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Perceptions of the esthetics of the anterior-posterior position of maxillary central incisors in individuals of four ethnicities as evaluated by orthodontists and four ethnicities of layperson

Protocol #: 19-0741

Location: Dental Clinic

Using Oscillometry in Toddler Aerodigestive Patients to Monitor Lung Function Response to Treatment

In this study, we will 1. Assess different mouthpiece options to help make the test easier to do in young children 2. Obtain AOS measurements in children who are patients in the aerodigestive clinic at Children's Hospital Colorado 3. Compare these measurements to those obtained in chil...

Protocol #: 21-2637

Location: Childrens Hospital Colorado

Harnessing Cells from Human Milk; Linking Lactation to Metabolism

In this study: - Participants will complete 2 study visits (in late pregnancy & 2 wks postpartum) - Participants will have their milk production measured and provide blood and breastmilk samples If you join the study, you will be part of the study for up to a month and a half, lasting...

Protocol #: 21-2835

Location: CTRC Inpatient, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

PANDEMIC RESPONSE REPOSITORY - MICROBIAL AND IMMUNE SURVEILLANCE AND EPIDEMIOLOGY (PREMISE): ENTEROVIRUS D68 (EV-D68) PILOT STUDY

Protocol #: 21-3488

Location: Childrens Hospital Colorado

The American Lung Association (ALA) Lung Health Cohort

Protocol #: 21-4835

Location: University of Colorado Hospital

Understanding How Sleep Health Affects Recovery from Adolescent Concussion

We will conduct a prospective cohort study, with two groups (concussed and control). They will undergo an initial assessment (within 14 days of concussion) and a follow up ~28 days post-concussion. Controls will follow a similar timeline. During the ~two-week period between Visits 1 & 2, p...

Protocol #: 22-0316

Location: Childrens Hospital Colorado

Distinguishing REM Sleep Behavior Disorder from Trauma Associated Sleep Disorder

Protocol #: 22-1244

Location: Outpatient CTRC, University of Colorado Hospital