Your search for "Healthy Volunteers" found 66 matches:
Research about alternative ways to measure the amount of hormones from a birth control pill

Participation will last up to 22 days and consist of three study visits. Participation will include taking one pack of birth control pills, containing both desogestrel and ethinyl estradiol. Participants will spend one day (8 hours) in clinic and receive an intravenous (IV) catheter for mu...more >

Protocol #: 21-3936

Location: Comprehensive Women's Health Center

Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics

Protocol #: 21-3590

Locations: Outpatient CTRC; University of Colorado Hospital

Effects of complementary feeding on infant growth and gut health

Your baby may be eligible if they are: - Breastfed and/or formula fed - Younger than five months of age - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a seven month-long study, from 5 to 12 months of age, with visits occurring every month. ...more >

Protocol #: 20-2232

Location: Childrens Hospital Colorado

Contraceptive Hormone and Reward Measurement (CHARM Study)

The study is examining the effects of hormonal oral contraceptives (OCPs) on brain processes and emotional wellbeing. Study participants will: Participate in 3 study sessions, one online and two in-person, over the course of 2 months. Complete interviews and questionnaires Taking a...more >

Protocol #: 21-3530

Locations: Brain Imaging Center (BIC); Outpatient CTRC

Opioid modulation and neural reward activation in healthy adults

Protocol #: 21-2886

Locations: Brain Imaging Center (BIC); Outpatient CTRC; University of Colorado Hospital

Premature Vascular Aging in Women following an In Vitro Fertilization Pregnancy

Main Procedures Involved: Ultrasound of blood vessels, blood draws, 24-hour blood pressure monitoring, sleep monitoring, body composition testing...more >

Protocol #: 21-2903

Locations: Outpatient CTRC; University of Colorado Hospital

Using Oscillometry in Toddler Aerodigestive Patients to Monitor Lung Function Response to Treatment

This study plans to learn more about how a breathing test called oscillometry can help clinical care providers monitor lung health in young children. Oscillometry is an effort-independent lung function test that measures airway resistance and obstruction and lung stiffness during normal br...more >

Protocol #: 21-2637

Location: Childrens Hospital Colorado

Improving Sleep in Healthcare Providers: Effects of Bose Noise-Masking Sleepbuds (Better Sleep Research Study)

Study participants will: 1. Take part in 3 study phases lasting up to 10 days total, a baseline assessment, an at-home intervention, and a post-intervention visit 2. Collect sleep data remotely 3. Complete interviews and questionnaires 4. Get to keep the Bose Noise-Masking Sleepbuds...more >

Protocol #: 21-2676

Location: University of Colorado Hospital

Role of microvascular insulin resistance and cardiorespiratory fitness in diabetes

Participants will undergo baseline testing of heart and blood vessel function, skeletal muscle function by biopsy, MRIs, and exercise testing. Participants will then complete a 15 week exercise training program, and all testing will be repeated. There are 11 study visits total, and partici...more >

Protocol #: 20-2723

Locations: CTRC Inpatient; Outpatient CTRC; University of Colorado Hospital

Nexplanon Extension Trial Study

-11 visits over 27 months -Physical exam, pelvic exam, Pap smear (if needed), STI screening -Blood draws -Daily e-diary completion ...more >

Protocol #: 20-2734

Location: Comprehensive Women's Health Center

Perceptions of the esthetics of the anterior-posterior position of maxillary central incisors in individuals of four ethnicities as evaluated by orthodontists and four ethnicities of layperson

Protocol #: 19-0741

Location: Dental Clinic

Evaluation of Intestinal Permeability and Chronic Inflammation in Patients with Type 2 Diabetes and Obesity Compared to Healthy Lean Controls (IDOS)

Participants will complete 2-3 visits- a screening visit and a testing visit. Some participants will be asked to split screening into 2 visits. All visits include blood draws and the testing visit includes blood draws and frequent urine samples. Participants will also be asked to provide a...more >

Protocol #: 20-2179

Locations: Outpatient CTRC; University of Colorado Hospital

Blueberry intake and infant gut health

Your breastfed baby may be eligible if they are: - Younger than six months of age - Exclusively breastfed - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every other month. The first and last ...more >

Protocol #: 20-1659

Location: Childrens Hospital Colorado

Disordered Eating, Energy Availability, and Quality of Life in Adolescent Athletes

Participants will receive a DEXA scan and will wear a FitBit for a week to track HR, sleep, and exercise. The participant will also log their food intake for the week. Compensation included. ...more >

Protocol #: 20-1681

Locations: Childrens Hospital Colorado; Outpatient CTRC; University of Colorado Hospital

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth (PUBERTY)

This study will involve 6 research visits at 3 timepoints for transgender individuals (before starting estrogen and 6 and 12 months after starting estrogen). No medications are given as a part of this study. Cisgender (non-transgender) participants will have 4 visits at two timepoints ...more >

Protocol #: 19-1226

Locations: Childrens Hospital Colorado; University of Colorado Hospital

A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18 Years and Older (mRNA-1273-P301)

Protocol #: 20-1619

Locations: Outpatient CTRC; University of Colorado Hospital

Colorado Nurses Experience with COVID-19

The purpose of the study is to find out the experiences of nurses who cared or prepared to care for COVID-19 patients. If you join the study you will help us learn about what nurses are going through during this pandemic time. You will provide insight to how nurses can improve or change th...more >

Protocol #: 20-6039

Locations: Boulder Health Center; Broomfield Hospital; Cherry Creek Medical Center; Grandview Hospital; Greeley Campus; Harmony Campus; Highlands Ranch Hospital; Lone Tree Medical Center; Long's Peak Hospital; Medical Center of the Rockies; Memorial Hospital Central; Memorial Hospital North; Pikes Peak Regional Hospital; Poudre Valley Hospital; Steadman Hawkins Clinic - Denver (Inverness); UCHealth Central Park Medical Center; UCHealth Internal Medical Clinic - Lowry; UCHealth Inverness; University of Colorado Hospital; Yampa Valley Medical Center

Salmon intake and gut health in adults

You may be eligible if: - You are between 30 and 70 years old - Your BMI is between 25 and 40 (check with this BMI calculator https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmi-m.htm) - Exercise 3 hours/week or less - Not on any glucose lowering medications This study co...more >

Protocol #: 20-1033

Locations: Outpatient CTRC; University of Colorado Hospital

Healthy Behaviors Study

How do childhood experiences shape health behaviors in adulthood? ...more >

Protocol #: 20-0578

Location: Sheridan Health Services

Validation of the Apollo EE Device, Indirect Calorimetry

Protocol #: 20-0317

Locations: Anschutz Health and Wellness; Outpatient CTRC; University of Colorado Hospital

Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Men Compared to Age Group-Matched Transgender Women and Cisgender Adults

Transgender men (i.e., assigned female at birth but identify as male) taking testosterone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o No history of cancer, diabetes or heart d...more >

Protocol #: 19-2323

Locations: Anschutz Health and Wellness; Outpatient CTRC; University of Colorado Hospital

The effect of rifampin on etonogestrel concentrations in contraceptive implant users

-2 visits lasting 30 minutes -Visit includes a blood draw, pregnancy test, and vital measurements....more >

Protocol #: 19-2829

Locations: Comprehensive Women's Health Center; Department Specific Free Standing Clinic

Birth Control Hormonal Pill Study

-9 visits over 13.5 months -Physical exam, pelvic exam -Trans-vaginal ultrasound, blood draws -Daily e-diary completion...more >

Protocol #: 19-2895

Location: Comprehensive Women's Health Center

Birth Control Hormonal Injection/Shot Study

-36 visits over 9 months -Physical Exam, Pelvic Exam-On screening Visit and Exit visit only -Trans-Vaginal Ultrasound, Blood draws-On every visit -Bleeding Diaries-will be filled collected weekly after Visit 3...more >

Protocol #: 19-2820

Location: Comprehensive Women's Health Center

Microfluidic models of bleeding and thrombosis

This study plans to learn more about how blood composition affects the formation of blood clots and to identify how individuals respond to commons drugs like anticoagulants and hormone treatments. ...more >

Protocol #: 19-2408

Locations: Department Specific Free Standing Clinic; Hemophilia and Thrombosis Center (HTC); University of Colorado Hospital

Effects of puberty and pubertal suppression on insulin sensitivity, metabolic rate and vascular health

This study will involve 4-5 in person visits. There will be screening visit for some patients and then a baseline visit over two days. The first day will involve an IV and drinking a sugary drink with blood draws as well as measuring the resting metabolic rate and answering questionnaires....more >

Protocol #: 19-2109

Locations: Childrens Hospital Colorado; Outpatient CTRC; University of Colorado Hospital

Gait Analysis of Femoroacetabular Impingement Patients

Protocol #: 16-1934

Location: Childrens Hospital Colorado

Allen CU-UCSD Transition to RA Project: Blood and Flu

Protocol #: 19-1150

Locations: Barbara Davis Center; University of Colorado Hospital

Sex effects on the neurobiology of eating behaviors in Veterans with overweight/obesity

Participants will complete: - 2 to 4 MRI scans - Food, attention, and mood questionnaires - Blood draws for measuring hormones Participants will be compensated for their time...more >

Protocol #: 19-0940

Locations: Outpatient CTRC; Rocky Mountain Regional VA Medical Center; University of Colorado Hospital

Neurophysiological Correlates V: 31Jan18

Protocol #: 16-1480

Location: Childrens Hospital Colorado

The contributions of age related changes in the sound localization pathway to central hearing loss

This study plans to learn more about how age affects the way we process sounds we hear. If you join the study, you will come into our Auditory Lab on the Anschutz Medical Campus 4-6 times and complete hearing assessments and questionnaires. ...more >

Protocol #: 19-1213

Location: Department Specific Free Standing Clinic

The Neural Underpinnings of Disinhibited Eating Behavior in Adolescents with and without Obesity

Protocol #: 19-1171

Location: University of Colorado Hospital

Sex-based differences in the neuronal mechanisms of food intake behavior

Participants will: -Complete 2 to 4 MRI scans -Complete food, attention, and mood questionnaires -Complete blood draws for measuring hormones -Receive a free Fitbit...more >

Protocol #: 19-1148

Locations: Outpatient CTRC; University of Colorado Hospital

Cardiopulmonary and Right Ventricular Function in Health and Disease

The primary objective of this research protocol is to advance the understanding of cardiopulmonary and right ventricular (RV) performance among individuals with cardiomyopathy (heart failure with reduced ejection fraction [HFrEF], heart failure with preserved ejection fraction [HFpEF]), as...more >

Protocol #: 19-1141

Locations: CTRC Inpatient; University of Colorado Hospital

Molecular Transducers of Physical Activity Consortium (MoTrPAC) - Adult

Protocol #: 18-0220

Locations: Outpatient CTRC; University of Colorado Hospital

The TULIP Study - Tissue-specific mechanisms UnderLying the unique Insulin resistance Phenotype in T1D

You might be eligible if you: • Are between 20 and 45 years of age and are not obese (body mass index <30 kg/m2) • Do not have a history of cardiovascular disease (heart attack, stroke, coronary bypass surgery or angioplasty) • Are not taking statins for high cholesterol • Do not h...more >

Protocol #: 19-0856

Locations: Barbara Davis Center; Outpatient CTRC; University of Colorado Hospital

Solid foods and infant growth

Your baby may be eligible if they are: - Exclusively breastfed - Younger than six months of age - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every month. The first visit, 9-month visit, an...more >

Protocol #: 19-0546

Location: Childrens Hospital Colorado

Multiomics Investigation of Marijuana Use

This research study seeks to learn more about biomarkers and biological pathways associated with marijuana use. We are enrolling adults who are marijuana users or non-users. The study involves filling out online surveys and one on-campus visit to give a blood, urine, and hair sample. If yo...more >

Protocol #: 18-0853

Location: University of Colorado Hospital

Bioenergetic and Metabolic Consequences of the Loss of Gonadal Function- 2018

This research study is investigating the roles of estrogen (female sex hormone) and FSH, or follicle-stimulating hormone, on cortisol (a stress hormone), fat gain, and disease risk....more >

Protocol #: 18-2483

Locations: Outpatient CTRC; University of Colorado Hospital

Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Women Compared to Age Group-Matched Cisgender Adults

Do you qualify? • Transgender women (i.e., assigned male at birth but identify as female) taking estradiol and spironolactone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o...more >

Protocol #: 18-2258

Locations: Anschutz Health and Wellness; Outpatient CTRC; Rocky Mountain Regional VA Medical Center; University of Colorado Hospital

CU Faces of Hope-Genetics of Craniofacial and Dental Development Research Study

This study plans to collect samples to create a database of patients with various syndromes that affect the way bones of the face are formed, termed “craniofacial”. These samples will support a new research program, named CU Faces of Hope, which involves a team of researchers and doctors ...more >

Protocol #: 18-1916

Location: Childrens Hospital Colorado

The Associations between EIT and Clinical Measures during Standard of Care Procedures in Patients with Respiratory Disease: A Preliminary Study

Protocol #: 18-1843

Location: Childrens Hospital Colorado

Identifying Predictors of Poor Health-Related Quality-of-Life among Pediatric Hematopoietic Stem Cell Donors

Protocol #: 18-1997

Location: Childrens Hospital Colorado

Early iron exposure on the gut microbiota in young infants

This is a four month-long study, beginning at birth. The first study visit is conducted at the University of Colorado Hospital and the last visit takes place at Children’s Hospital Colorado. The other four visits are conducted in your home. Formula is provided to all study participants for...more >

Protocol #: 18-1317

Location: Childrens Hospital Colorado

Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis (StopRA)

Protocol #: 15-1868

Locations: Barbara Davis Center; UCD Barbara Davis Center; University of Colorado Hospital

Identifying Environmental Triggers of Smoking Behaviors in Low-income Communities

Protocol #: 18-0052

Locations: Department Specific Free Standing Clinic; University of Colorado Cancer Center; University of Colorado Hospital

PLACENTAL PROTEINS AND PREMATURITY (P3 STUDY)

This study plans to learn more about why babies born prematurely sometimes can have problems with infections, breathing, feeding, vision, and brain function....more >

Protocol #: 18-0637

Locations: Outpatient CTRC; University of Colorado Hospital

Defining Molecular Phenotypes of Exacerbation-Prone Asthmatics (ENIGMA)

We want to learn more about asthma and how stuff in the air, like pollution and allergens, can make asthma worse in children. To do this we want to look at kids with and without asthma. If you join the study, you will participate in a remote consent visit, a clinic visit and a remote home...more >

Protocol #: 17-1416

Location: Childrens Hospital Colorado

Precision Approach to PPI Therapy in Gastroesophageal reflux disease

Over the past 25 years, RALS has been increasingly, and often incorrectly, diagnosed and has emerged as a point of controversy and confusion. Despite the limitations of current diagnostic tests and therapeutic strategies, recent advances in gastoresophageal reflux disease offer tremendous...more >

Protocol #: 18-0205

Location: University of Colorado Hospital

EA1151: Tomosynthesis Mammographic Imaging Screening Trial (TMIST)

Participants in this trial will be randomized to receive either 2D or 3D mammograms for the first 5 years of the research study, either ever year or every other year depending on personal risk factors. Information will be collected on breast cancer status for 8 years in total. ...more >

Protocol #: 18-0392

Locations: Highlands Ranch Hospital; Outpatient CTRC; University of Colorado Hospital

Cerebrovascular Function in CKD and ADPKD: A Cross-Sectional Study

Protocol #: 17-2135

Location: Renal Research Center

Mitochondrial targeted antioxidant supplementation and diastolic function in healthy men and women

As we get older, our cardiovascular health worsens. This can lead to high blood pressure and heart disease. In this study we want to find out what causes cardiovascular health to worsen in older men and women. Also we want to find out what happens to the cardiovascular system when we take ...more >

Protocol #: 17-1782

Locations: Outpatient CTRC; University of Colorado Hospital

Improving our knowledge about maternal behavior and its potential effect on infant outcomes

Protocol #: 17-2033

Locations: CU John C. Hobbins Perinatal Center; CU Parker Perinatal Center; Denver Health and Hospital Authority; Department Specific Free Standing Clinic; University of Colorado Hospital

Rapid measurements of water isotopes in human breath and saliva for doubly labeled water analysis V: 04/03/18

Protocol #: 16-2203

Location: University of Colorado Hospital

Human Trisome Project

Additional information about this study can be found at www.trisome.org....more >

Protocol #: 15-2170

Locations: Childrens Hospital Colorado; University of Colorado Hospital

Appetite Regulation in Older-Aged Obese Individuals

Participants needed for a research study that plans to examine the effects of age and body weight on food intake, appetite regulation, and brain responses to food....more >

Protocol #: 15-1511

Location: University of Colorado Hospital

Tissue-specific effects of insufficient sleep

The proposed project is a within-subject consecutive design examining 14 healthy individuals after baseline and after 4 nights of insufficient sleep. Following 7 days of at-home habitual sleep of 9 hours/night and a 3-day lead-in energy balanced diet, participants will be admitted for a 6-...more >

Protocol #: 17-0533

Locations: CTRC Inpatient; CTRC-UC Boulder; University of Colorado Hospital

Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex

Participants will undergo baseline testing of heart and blood vessel function as well as skeletal muscle function and exercise ability. Participants will then do cardiovascular exercise for 15 weeks, and all testing will be repeated....more >

Protocol #: 17-0356

Locations: Outpatient CTRC; University of Colorado Hospital

Effects of Your Genetics on the Contraceptive Implant (Nexplanon®)

1 visit lasting 30 minutes. Visit includes a questionnaire and a blood draw....more >

Protocol #: 16-2462

Location: University of Colorado Hospital

Reprometabolic Syndrome Mediates Subfertility in Obesity

Protocol #: 15-1052

Locations: CTRC Inpatient; Outpatient CTRC; University of Colorado Hospital

The impact of estrogen status on the biological function of brown adipose tissue in women measured using quantitative PET/CT

The physiological relevance of brown adipose tissue in humans is largely unknown. We have shown that suppressing ovarian function in premenopausal women reduces resting energy expenditure (REE), and this is prevented by adding back estradiol (E2). Our preliminary data suggest that this may...more >

Protocol #: 16-1479

Locations: CTRC-adult; Outpatient CTRC; University of Colorado Hospital

Effect of Mechanical Circulatory Support on Exercise Capacity in Heart Failure

Protocol #: 16-1635

Locations: Colorado Research Center; CTRC-adult; Outpatient CTRC; University of Colorado Hospital

Cardiovascular consequences of hypogonadism in men

Protocol #: 15-1162

Locations: Outpatient CTRC; Rocky Mountain Regional VA Medical Center; University of Colorado Hospital

Is disruption of the human gut microbial environment associated with cognitive impairment following chemotherapy for breast cancer?

Protocol #: 16-2138

Location: University of Colorado Hospital

A double-blind, placebo-controlled crossover study comparing the analgesic efficacy of cannabis versus oxycodone

Protocol #: 14-1909

Locations: CTRC-adult; Outpatient CTRC; University of Colorado Hospital

Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer (ORIEN)

Protocol #: 15-1110

Locations: Memorial Hospital Central; Memorial Hospital North; Poudre Valley Hospital; University of Colorado Hospital