Your search for "Healthy Volunteers" found 79 matches:
Solid foods and infant growth

Your baby may be eligible if they are: - Exclusively breastfed - Younger than six months of age - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every month. The first visit, 9-month visit, an...

Protocol #: 19-0546

Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Women Compared to Age Group-Matched Cisgender Adults

Do you qualify? • Transgender women (i.e., assigned male at birth but identify as female) taking estradiol and spironolactone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o...

Protocol #: 18-2258

Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Men Compared to Age Group-Matched Transgender Women and Cisgender Adults

Transgender men (i.e., assigned female at birth but identify as male) taking testosterone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o No history of cancer, diabetes or heart d...

Protocol #: 19-2323

Sex effects on the neurobiology of eating behaviors in Veterans with overweight/obesity

Protocol #: 19-0940

Microfluidic models of bleeding and thrombosis

This study plans to learn more about how blood composition affects the formation of blood clots and to identify how individuals respond to commons drugs like anticoagulants and hormone treatments. ...

Protocol #: 19-2408

Birth Control Hormonal Injection/Shot Study

-36 visits over 9 months -Physical Exam, Pelvic Exam-On screening Visit and Exit visit only -Trans-Vaginal Ultrasound, Blood draws-On every visit -Bleeding Diaries-will be filled collected weekly after Visit 3...

Protocol #: 19-2820

Birth Control Hormonal Pill Study

-9 visits over 13.5 months -Physical exam, pelvic exam -Trans-vaginal ultrasound, blood draws -Daily e-diary completion...

Protocol #: 19-2895

Nexplanon Extension Trial Study

-11 visits over 27 months -Physical exam, pelvic exam, Pap smear (if needed), STI screening -Blood draws -Daily e-diary completion ...

Protocol #: 20-2734

The effect of rifampin on etonogestrel concentrations in contraceptive implant users

-2 visits lasting 30 minutes -Visit includes a blood draw, pregnancy test, and vital measurements....

Protocol #: 19-2829

Salmon intake and gut health in adults

You may be eligible if: - You are between 30 and 70 years old - Your BMI is between 25 and 40 (check with this BMI calculator https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmi-m.htm) - Exercise 3 hours/week or less - Not on any glucose lowering medications This study co...

Protocol #: 20-1033

Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex

Participants will undergo baseline testing of heart and blood vessel function as well as skeletal muscle function and exercise ability. Participants will then do cardiovascular exercise for 15 weeks, and all testing will be repeated....

Protocol #: 17-0356

Evaluation of Intestinal Permeability and Chronic Inflammation in Patients with Type 2 Diabetes and Obesity Compared to Healthy Lean Controls (IDOS)

Participants will complete 2-3 visits- a screening visit and a testing visit. Some participants will be asked to split screening into 2 visits. All visits include blood draws and the testing visit includes blood draws and frequent urine samples. Participants will also be asked to provide a...

Protocol #: 20-2179

Cerebrovascular Function in CKD and ADPKD: A Cross-Sectional Study

Protocol #: 17-2135

Effects of complementary feeding on infant growth and gut health

Your baby may be eligible if they are: - Breastfed and/or formula fed - Younger than five months of age - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a seven month-long study, from 5 to 12 months of age, with visits occurring every month. ...

Protocol #: 20-2232

The impact of estrogen status on the biological function of brown adipose tissue in women measured using quantitative PET/CT

The physiological relevance of brown adipose tissue in humans is largely unknown. We have shown that suppressing ovarian function in premenopausal women reduces resting energy expenditure (REE), and this is prevented by adding back estradiol (E2). Our preliminary data suggest that this may...

Protocol #: 16-1479

Blueberry intake and infant gut health

Your breastfed baby may be eligible if they are: - Younger than six months of age - Exclusively breastfed - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every other month. The first and last ...

Protocol #: 20-1659

Research about alternative ways to measure the amount of hormones from a birth control pill

Participation will last up to 22 days and consist of three study visits. Participation will include taking one pack of birth control pills, containing both desogestrel and ethinyl estradiol. Participants will spend one day (8 hours) in clinic and receive an intravenous (IV) catheter for mu...

Protocol #: 21-3936

Effects of Your Genetics on the Contraceptive Implant (Nexplanon®)

1 visit lasting 30 minutes. Visit includes a questionnaire and a blood draw....

Protocol #: 16-2462

Early iron exposure on the gut microbiota in young infants

This is a four month-long study, beginning at birth. The first study visit is conducted at the University of Colorado Hospital and the last visit takes place at Children’s Hospital Colorado. The other four visits are conducted in your home. Formula is provided to all study participants for...

Protocol #: 18-1317

Improving Sleep in Healthcare Providers: Effects of Bose Noise-Masking Sleepbuds (Better Sleep Research Study)

Study participants will: 1. Take part in 3 study phases lasting up to 10 days total, a baseline assessment, an at-home intervention, and a post-intervention visit 2. Collect sleep data remotely 3. Complete interviews and questionnaires 4. Get to keep the Bose Noise-Masking Sleepbuds...

Protocol #: 21-2676

Colorado Pulmonary Alcohol Research Consortium

We are looking for volunteers to serve as control subjects to be compared to people who drink heavily in a research project that examines substances collected from inside the lungs....

Protocol #: 12-0181

Location: CTRC-adult, University of Colorado Hospital

Investigational Male Birth Control Gel

This clinical trial is an experimental research study using a potential new form of male birth control who want to avoid a pregnancy with their sexual partner....

Protocol #: 21-3956

Nexplanon Birth Control Implant Use When Primarily Using a Combined Birth Control Pill

Participants will use the birth control pills as their main method of birth control and have the implant as a continuous back-up method. ...

Protocol #: 20-1945

The Influence of Combined Oral Contraceptives on Weight: A 6-month Observational Study

Approximately 15 million women of reproductive age women in the United States have overweight or obesity and use the combined estrogen and progestin oral contraceptive pill (COC). Although many women report weight gain as a side effect of COCs, a conclusive link between COC use and weight ...

Protocol #: 21-3969

Location: CTRC-adult, University of Colorado Hospital

Role of microvascular insulin resistance and cardiorespiratory fitness in diabetes

Protocol #: 20-2723

Nexplanon Use in Those Primarily Choosing Combined Birth Control Pills

Participants will use the birth control pills as their main method of birth control and have the implant as a continuous back-up method. Participants in the study will have 4-5 visits during the 12 months of the study. ...

Protocol #: 20-1945

Location: CU Anschutz non-hospital research facilities

Research about the Potential for the Contraceptive Implant as Emergency Contraception

Are you a healthy female between the ages of 18-40? Are you interested in starting Nexplanon®, hormonal birth control that goes in your arm? Are you interested in how your body works, specifically in regard to ovulation? This study is determining if when placing an etonogestrel implant ...

Protocol #: 21-5026

PANTHER: Puberty, diAbetes, aNd THe kidnEys, when eustress becomes distress

The study visits will be at the outpatient Clinical & Translational Research Center (CTRC) at Children’s Hospital Colorado. This study takes place over 3 years. The day 1 and day 2 visits are the same each year and will take place approx. 12 months apart. ...

Protocol #: 21-3019

Location: Childrens Hospital Colorado

Prolonged Sedentary Behavior in Older Women with and without Type 2 Diabetes: Knowledge, Engagement, and Relationship to Cardiometabolic Risk

Are you interested in participating in a research study to understand the health effects of the time we spend sitting? The ACTIVE Research Lab is looking for: • Women • 60 to 75 years of age • Non-smoker • If Type 2 Diabetes, not being treated with insulin • BMI 25-40 kg/m2 (check ...

Protocol #: 19-2758

SHINGLES VACCINE RESEARCH STUDY PERSONS AGE 50 AND OLDER

We are recruiting for 2 groups; you may be eligible to participate if you are • Age 50 or older • In general good health, and • Have never had shingles, and * Received a shingles vaccine = 5 years ago and can provide documen...

Protocol #: 18-0580

Location: CU Anschutz non-hospital research facilities

Are you interested in having your IUD removed and participating in research?

You may qualify if you: • Are healthy and between the ages of 18-45 • Currently have an IUD in place • Seeking IUD removal • Willing to insert and remove a menstrual cup prior to IUD removal ...

Protocol #: 21-4267

Location: CU Anschutz non-hospital research facilities

Premature Vascular Aging in Women following an In Vitro Fertilization Pregnancy

Ultrasound of blood vessels, blood draw, 24-hour blood pressure monitoring, body composition and bone mineral density testing Compensation is provided....

Protocol #: 21-2903

Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics

Inclusion criteria: - Women aged 18-55 years - Non-smoking - Not taking medications to treat high blood pressure or cholesterol ...

Protocol #: 21-3590

Physical Activity and Autosomal Dominant Polycystic Kidney Disease

This research study is being conducted to learn more about physical activity habits in those with ADPKD....

Protocol #: 22-0072

Location: Renal Research Center

Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer (ORIEN)

Protocol #: 15-1110

Location: Memorial Hospital Central, Memorial Hospital North, Poudre Valley Hospital, University of Colorado Hospital

Real-Time Assessment of Lung Structure and Function in Children and Young Adults with CF using Electrical Impedance Tomography

Single visit to Children's Hospital Colorado - During this visit your height, weight, date of birth, and gender will be recorded. You will also have some tests done including pulmonary function testing (spirometry), EIT, and multiple breath washout (MBW)....

Protocol #: 22-0114

Location: Childrens Hospital Colorado

A double-blind, placebo-controlled crossover study comparing the analgesic efficacy of cannabis versus oxycodone

Protocol #: 14-1909

Location: CTRC-adult, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Is disruption of the human gut microbial environment associated with cognitive impairment following chemotherapy for breast cancer?

Protocol #: 16-2138

Location: University of Colorado Hospital

Cardiovascular consequences of hypogonadism in men

Protocol #: 15-1162

Location: Outpatient CTRC, Rocky Mountain Regional VA Medical Center, University of Colorado Hospital

Effect of Mechanical Circulatory Support on Exercise Capacity in Heart Failure

Protocol #: 16-1635

Location: Colorado Research Center, CTRC-adult, Outpatient CTRC, University of Colorado Hospital

Comparing WatchPAT to Polysomnography in the Assessment of Sleep Disordered Breathing in At-Risk Adolescents

Participants will wear the WatchPAT device during their PSG appointment and the results between the two tests will be compared....

Protocol #: 22-0847

Location: Childrens Hospital Colorado

Tissue-specific effects of insufficient sleep

The proposed project is a within-subject consecutive design examining 14 healthy individuals after baseline and after 4 nights of insufficient sleep. Following 7 days of at-home habitual sleep of 9 hours/night and a 3-day lead-in energy balanced diet, participants will be admitted for a 6-...

Protocol #: 17-0533

Location: CTRC Inpatient, CTRC-UC Boulder, University of Colorado Hospital

Human Trisome Project

Additional information about this study can be found at www.trisome.org....

Protocol #: 15-2170

Location: Childrens Hospital Colorado, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Rapid measurements of water isotopes in human breath and saliva for doubly labeled water analysis V: 04/03/18

Protocol #: 16-2203

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Improving our knowledge about maternal behavior and its potential effect on infant outcomes

Protocol #: 17-2033

Location: CU John C. Hobbins Perinatal Center, CU Parker Perinatal Center, Denver Health and Hospital Authority, Department Specific Free Standing Clinic, University of Colorado Hospital

Mitochondrial targeted antioxidant supplementation and diastolic function in healthy men and women

As we get older, our cardiovascular health worsens. This can lead to high blood pressure and heart disease. In this study we want to find out what causes cardiovascular health to worsen in older men and women. Also we want to find out what happens to the cardiovascular system when we take ...

Protocol #: 17-1782

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

EA1151: Tomosynthesis Mammographic Imaging Screening Trial (TMIST)

Participants in this trial will be randomized to receive either 2D or 3D mammograms for the first 5 years of the research study, either ever year or every other year depending on personal risk factors. Information will be collected on breast cancer status for 8 years in total. ...

Protocol #: 18-0392

Location: Highlands Ranch Hospital, Outpatient CTRC, University of Colorado Hospital

Defining Molecular Phenotypes of Exacerbation-Prone Asthmatics (ENIGMA)

We want to learn more about asthma and how stuff in the air, like pollution and allergens, can make asthma worse in children. To do this we want to look at kids with and without asthma. If you join the study, you will participate in a remote consent visit, a clinic visit and a remote home...

Protocol #: 17-1416

Location: Childrens Hospital Colorado

PLACENTAL PROTEINS AND PREMATURITY (P3 STUDY)

This study plans to learn more about why babies born prematurely sometimes can have problems with infections, breathing, feeding, vision, and brain function....

Protocol #: 18-0637

Location: Outpatient CTRC, University of Colorado Hospital

Identifying Environmental Triggers of Smoking Behaviors in Low-income Communities

Protocol #: 18-0052

Location: Department Specific Free Standing Clinic, University of Colorado Cancer Center, University of Colorado Hospital

Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis (StopRA)

Protocol #: 15-1868

Location: Barbara Davis Center, UCD Barbara Davis Center, University of Colorado Hospital

Identifying Predictors of Poor Health-Related Quality-of-Life among Pediatric Hematopoietic Stem Cell Donors

Protocol #: 18-1997

Location: Childrens Hospital Colorado

The Associations between EIT and Clinical Measures during Standard of Care Procedures in Patients with Respiratory Disease: A Preliminary Study

Protocol #: 18-1843

Location: Childrens Hospital Colorado

CU Faces of Hope-Genetics of Craniofacial and Dental Development Research Study

This study plans to collect samples to create a database of patients with various syndromes that affect the way bones of the face are formed, termed “craniofacial”. These samples will support a new research program, named CU Faces of Hope, which involves a team of researchers and doctors ...

Protocol #: 18-1916

Location: Childrens Hospital Colorado

Bioenergetic and Metabolic Consequences of the Loss of Gonadal Function- 2018

This research study is investigating the roles of estrogen (female sex hormone) and FSH, or follicle-stimulating hormone, on cortisol (a stress hormone), fat gain, and disease risk....

Protocol #: 18-2483

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Multiomics Investigation of Marijuana Use

This research study seeks to learn more about biomarkers and biological pathways associated with marijuana use. We are enrolling adults who are marijuana users or non-users. The study involves filling out online surveys and one on-campus visit to give a blood, urine, and hair sample. If yo...

Protocol #: 18-0853

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Molecular Transducers of Physical Activity Consortium (MoTrPAC) - Adult

Protocol #: 18-0220

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Cardiopulmonary and Right Ventricular Function in Health and Disease

The primary objective of this research protocol is to advance the understanding of cardiopulmonary and right ventricular (RV) performance among individuals with cardiomyopathy (heart failure with reduced ejection fraction [HFrEF], heart failure with preserved ejection fraction [HFpEF]), as...

Protocol #: 19-1141

Location: CTRC Inpatient, University of Colorado Hospital

Sex-based differences in the neuronal mechanisms of food intake behavior

Participants will: -Complete 2 to 4 MRI scans -Complete food, attention, and mood questionnaires -Complete blood draws for measuring hormones -Receive a free Fitbit...

Protocol #: 19-1148

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

The Neural Underpinnings of Disinhibited Eating Behavior in Adolescents with and without Obesity

Protocol #: 19-1171

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

The contributions of age related changes in the sound localization pathway to central hearing loss

This study plans to learn more about how age affects the way we process sounds we hear. If you join the study, you will come into our Auditory Lab on the Anschutz Medical Campus 4-6 times and complete hearing assessments and questionnaires. ...

Protocol #: 19-1213

Location: Department Specific Free Standing Clinic

Neurophysiological Correlates V: 31Jan18

Protocol #: 16-1480

Location: Childrens Hospital Colorado

Allen CU-UCSD Transition to RA Project: Blood and Flu

Protocol #: 19-1150

Location: Barbara Davis Center, University of Colorado Hospital

Gait Analysis of Femoroacetabular Impingement Patients

Protocol #: 16-1934

Location: Childrens Hospital Colorado

Effects of puberty and pubertal suppression on insulin sensitivity, metabolic rate and vascular health

This study will involve 4-5 in person visits. There will be screening visit for some patients and then a baseline visit over two days. The first day will involve an IV and drinking a sugary drink with blood draws as well as measuring the resting metabolic rate and answering questionnaires....

Protocol #: 19-2109

Location: Childrens Hospital Colorado, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Validation of the Apollo EE Device, Indirect Calorimetry

Protocol #: 20-0317

Location: Anschutz Health and Wellness, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Colorado Nurses Experience with COVID-19

The purpose of the study is to find out the experiences of nurses who cared or prepared to care for COVID-19 patients. If you join the study you will help us learn about what nurses are going through during this pandemic time. You will provide insight to how nurses can improve or change th...

Protocol #: 20-6039

Location: Boulder Health Center, Broomfield Hospital, Cherry Creek Medical Center, Grandview Hospital, Greeley Campus, Harmony Campus, Highlands Ranch Hospital, Lone Tree Medical Center, Longs Peak Hospital, Longs Peak Hospital, Medical Center of the Rockies, Memorial Hospital Central, Memorial Hospital North, Pikes Peak Regional Hospital, Poudre Valley Hospital, Steadman Hawkins Clinic - Denver (Inverness), UCHealth Central Park Medical Center, UCHealth Internal Medical Clinic - Lowry, UCHealth Inverness, University of Colorado Hospital, Yampa Valley Medical Center

A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18 Years and Older (mRNA-1273-P301)

Protocol #: 20-1619

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth (PUBERTY)

This study will involve 6 research visits at 3 timepoints for transgender individuals (before starting estrogen and 6 and 12 months after starting estrogen). No medications are given as a part of this study. Cisgender (non-transgender) participants will have 4 visits at two timepoints ...

Protocol #: 19-1226

Location: Childrens Hospital Colorado, University of Colorado Hospital

Disordered Eating, Energy Availability, and Quality of Life in Adolescent Athletes

Participants will receive a DEXA scan and will wear a FitBit for a week to track HR, sleep, and exercise. The participant will also log their food intake for the week. Compensation included. ...

Protocol #: 20-1681

Location: Childrens Hospital Colorado, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Perceptions of the esthetics of the anterior-posterior position of maxillary central incisors in individuals of four ethnicities as evaluated by orthodontists and four ethnicities of layperson

Protocol #: 19-0741

Location: Dental Clinic

Using Oscillometry in Toddler Aerodigestive Patients to Monitor Lung Function Response to Treatment

In this study, we will 1. Assess different mouthpiece options to help make the test easier to do in young children 2. Obtain AOS measurements in children who are patients in the aerodigestive clinic at Children's Hospital Colorado 3. Compare these measurements to those obtained in chil...

Protocol #: 21-2637

Location: Childrens Hospital Colorado

Skeletal Response to Simulated Night Shift (SPOTLIGHT Study)

Protocol #: 20-3013

Location: CTRC Inpatient, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Contraceptive Hormone and Reward Measurement (CHARM Study)

The study is examining the effects of hormonal oral contraceptives (OCPs) on brain processes and emotional wellbeing. Study participants will: Participate in 3 study sessions, one online and two in-person, over the course of 2 months. Complete interviews and questionnaires Taking a...

Protocol #: 21-3530

Location: Brain Imaging Center (BIC), Outpatient CTRC, Outpatient CTRC

Harnessing Cells from Human Milk; Linking Lactation to Metabolism

In this study: - Participants will complete 2 study visits (in late pregnancy & 2 wks postpartum) - Participants will have their milk production measured and provide blood and breastmilk samples If you join the study, you will be part of the study for up to a month and a half, lasting...

Protocol #: 21-2835

Location: CTRC Inpatient, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Investigating the Role of the Endocannabinoid System in Joint Pain

If you join the study, you will be asked to complete one 10-minute study visit at the Barbara Davis Center on the University of Colorado's Anschutz Medical Campus. During this visit, the study coordinator will first go through the consent process and confirm your eligibility, which may req...

Protocol #: 21-3357

Location: University of Colorado Hospital

PANDEMIC RESPONSE REPOSITORY - MICROBIAL AND IMMUNE SURVEILLANCE AND EPIDEMIOLOGY (PREMISE): ENTEROVIRUS D68 (EV-D68) PILOT STUDY

Protocol #: 21-3488

Location: Childrens Hospital Colorado

The American Lung Association (ALA) Lung Health Cohort

Protocol #: 21-4835

Location: University of Colorado Hospital

NightWare Therapeutic Platform for improving Cardiovascular Health in Adults With Nightmares Associated with PTSD

We are recruiting individuals who experience PTSD-associated nightmares to participate in a research study to help us understand if improving sleep quality, by reducing the impact of nightmares can improve cardiovascular health. We are recruiting volunteers who experience PTSD-related nig...

Protocol #: 21-5027

Location: Outpatient CTRC