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Premature Vascular Aging in Women following an In Vitro Fertilization Pregnancy
Main Procedures Involved: Ultrasound of blood vessels, blood draws, 24-hour blood pressure monitoring, sleep monitoring, body composition testing...more > Protocol #: 21-2903 Locations: Outpatient CTRC; University of Colorado Hospital |
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Using Oscillometry in Toddler Aerodigestive Patients to Monitor Lung Function Response to Treatment
This study plans to learn more about how a breathing test called oscillometry can help clinical care providers monitor lung health in young children. Oscillometry is an effort-independent lung function test that measures airway resistance and obstruction and lung stiffness during normal br...more > Protocol #: 21-2637 Location: Childrens Hospital Colorado |
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Improving sleep in healthcare providers: effects of Bose noise-masking Sleepbuds(tm)
Study participants will: 1. Participate in 2 study sessions, done online or in-person, over the course of 2 weeks 2. Wear sleep study devices for 10 nights (at home) 3. Complete interviews and questionnaires...more > Protocol #: 21-2676 Location: University of Colorado Hospital |
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Disordered Eating, Energy Availability, and Quality of Life in Adolescent Athletes
Participants will receive a DEXA scan and will wear a FitBit for a week to track HR, sleep, and exercise. The participant will also log their food intake for the week. Compensation included. ...more > Protocol #: 20-1681 Locations: Childrens Hospital Colorado; University of Colorado Hospital |
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Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth (PUBERTY)
This study will involve 6 research visits at 3 timepoints for transgender individuals (before starting estrogen and 6 and 12 months after starting estrogen). No medications are given as a part of this study. Cisgender (non-transgender) participants will have 4 visits at two timepoints ...more > Protocol #: 19-1226 Locations: Childrens Hospital Colorado; University of Colorado Hospital |
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Colorado Nurses Experience with COVID-19
The purpose of the study is to find out the experiences of nurses who cared or prepared to care for COVID-19 patients. If you join the study you will help us learn about what nurses are going through during this pandemic time. You will provide insight to how nurses can improve or change th...more > Protocol #: 20-6039 Locations: Boulder Health Center; Broomfield Hospital; Cherry Creek Medical Center; Grandview Hospital; Greeley Campus; Harmony Campus; Highlands Ranch Hospital; Lone Tree Medical Center; Long's Peak Hospital; Medical Center of the Rockies; Memorial Hospital Central; Memorial Hospital North; Pikes Peak Regional Hospital; Poudre Valley Hospital; Steadman Hawkins Clinic - Denver (Inverness); UCHealth Central Park Medical Center; UCHealth Internal Medical Clinic - Lowry; UCHealth Inverness; University of Colorado Hospital; Yampa Valley Medical Center |
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Use of accelerometers to improve estimation of the thermic effect of feeding in whole room calorimetry studies
What you receive for participating: -Personalized information about your energy expenditure ("metabolism") -Five total days of food -Monetary compensation...more > Protocol #: 20-0191 Location: University of Colorado Hospital |
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Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Men Compared to Age Group-Matched Transgender Women and Cisgender Adults
Transgender men (i.e., assigned female at birth but identify as male) taking testosterone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o No history of cancer, diabetes or heart d...more > Protocol #: 19-2323 Locations: Anschutz Health and Wellness; Outpatient CTRC; University of Colorado Hospital |
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Microfluidic models of bleeding and thrombosis
This study plans to learn more about how blood composition affects the formation of blood clots and to identify how individuals respond to commons drugs like anticoagulants and hormone treatments. ...more > Protocol #: 19-2408 Locations: Department Specific Free Standing Clinic; University of Colorado Hospital |
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Effects of puberty and pubertal suppression on insulin sensitivity, metabolic rate and vascular health
This study will involve 4-5 in person visits. There will be screening visit for some patients and then a baseline visit over two days. The first day will involve an IV and drinking a sugary drink with blood draws as well as measuring the resting metabolic rate and answering questionnaires....more > Protocol #: 19-2109 Locations: Childrens Hospital Colorado; University of Colorado Hospital |
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Sex effects on the neurobiology of eating behaviors in Veterans with overweight/obesity
Participants will complete: - 2 to 4 MRI scans - Food, attention, and mood questionnaires - Blood draws for measuring hormones Participants will be compensated for their time...more > Protocol #: 19-0940 Locations: Rocky Mountain Regional VA Medical Center; University of Colorado Hospital |
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The contributions of age related changes in the sound localization pathway to central hearing loss
This study plans to learn more about how age affects the way we process sounds we hear. If you join the study, you will come into our Auditory Lab on the Anschutz Medical Campus 4-6 times and complete hearing assessments and questionnaires. ...more > Protocol #: 19-1213 Location: Department Specific Free Standing Clinic |
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Cardiopulmonary and Right Ventricular Function in Health and Disease
The primary objective of this research protocol is to advance the understanding of cardiopulmonary and right ventricular (RV) performance among individuals with cardiomyopathy (heart failure with reduced ejection fraction [HFrEF], heart failure with preserved ejection fraction [HFpEF]), as...more > Protocol #: 19-1141 Location: University of Colorado Hospital |
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The TULIP Study - Tissue-specific mechanisms UnderLying the unique Insulin resistance Phenotype in T1D
You might be eligible if you: • Are between 20 and 45 years of age and are not obese (body mass index <30 kg/m2) • Do not have a history of cardiovascular disease (heart attack, stroke, coronary bypass surgery or angioplasty) • Are not taking statins for high cholesterol • Do not h...more > Protocol #: 19-0856 Locations: Barbara Davis Center; Outpatient CTRC; University of Colorado Hospital |
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Multiomics Investigation of Marijuana Use
This research study seeks to learn more about biomarkers and biological pathways associated with marijuana use. We are enrolling adults who are marijuana users or non-users. The study involves filling out online surveys and one on-campus visit to give a blood, urine, and hair sample. If yo...more > Protocol #: 18-0853 Location: University of Colorado Hospital |
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Bioenergetic and Metabolic Consequences of the Loss of Gonadal Function- 2018
This research study is investigating the roles of estrogen (female sex hormone) and FSH, or follicle-stimulating hormone, on cortisol (a stress hormone), fat gain, and disease risk....more > Protocol #: 18-2483 Location: University of Colorado Hospital |
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Novel Evaluations of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Women Compared to Age Group-Matched Cisgender Adults
Do you qualify? • Transgender women (i.e., assigned male at birth but identify as female) taking estradiol and spironolactone o Ages 18 to 40 or 50 to 75 years o In good general health o Have been on hormones for at least 1 year o No history of gonadectomy o...more > Protocol #: 18-2258 Locations: Anschutz Health and Wellness; Outpatient CTRC; Rocky Mountain Regional VA Medical Center; University of Colorado Hospital |
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A Phase 3, Multicenter, Open-Label Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual Bleeding
The study is a multicenter, open-label, evaluation of the efficacy and safety of LNG20 IUS for treatment of heavy menstrual bleeding....more > Protocol #: 18-2249 Locations: Comprehensive Women's Health Center; Comprehensive Womens Health Center; University of Colorado Hospital |
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CU Faces of Hope-Genetics of Craniofacial and Dental Development Research Study
This study plans to collect samples to create a database of patients with various syndromes that affect the way bones of the face are formed, termed “craniofacial”. These samples will support a new research program, named CU Faces of Hope, which involves a team of researchers and doctors ...more > Protocol #: 18-1916 Location: Childrens Hospital Colorado |
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A multi-center, single-blind, randomized clinical trial to compare two copper IUDs:Mona Lisa NT Cu380 Mini and ParaGard
A randomized, single-blind, phase IIb/III controlled clinical trial to measure contraceptive efficacy of Mona Lisa NT Cu380 Mini. ...more > Protocol #: 17-0225 Locations: Comprehensive Women's Health Center; Comprehensive Womens Health Center; University of Colorado Hospital |
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PLACENTAL PROTEINS AND PREMATURITY (P3 STUDY)
This study plans to learn more about why babies born prematurely sometimes can have problems with infections, breathing, feeding, vision, and brain function....more > Protocol #: 18-0637 Location: University of Colorado Hospital |
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Defining Molecular Phenotypes of Exacerbation-Prone Asthmatics (ENIGMA)
We want to learn more about asthma and how stuff in the air, like pollution and allergens, can make asthma worse in children. To do this we want to look at kids with and without asthma. If you join the study, you will participate in a remote consent visit, a clinic visit and a remote home...more > Protocol #: 17-1416 Location: Childrens Hospital Colorado |
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Precision Approach to PPI Therapy in Gastroesophageal reflux disease
Over the past 25 years, RALS has been increasingly, and often incorrectly, diagnosed and has emerged as a point of controversy and confusion. Despite the limitations of current diagnostic tests and therapeutic strategies, recent advances in gastoresophageal reflux disease offer tremendous...more > Protocol #: 18-0205 Location: University of Colorado Hospital |
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EA1151: Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Participants in this trial will be randomized to receive either 2D or 3D mammograms for the first 5 years of the research study, either ever year or every other year depending on personal risk factors. Information will be collected on breast cancer status for 8 years in total. ...more > Protocol #: 18-0392 Locations: Highlands Ranch Hospital; University of Colorado Hospital |
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Mitochondrial targeted antioxidant supplementation and diastolic function in healthy men and women
As we get older, our cardiovascular health worsens. This can lead to high blood pressure and heart disease. In this study we want to find out what causes cardiovascular health to worsen in older men and women. Also we want to find out what happens to the cardiovascular system when we take ...more > Protocol #: 17-1782 Location: University of Colorado Hospital |
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Human Trisome Project
Additional information about this study can be found at www.trisome.org....more > Protocol #: 15-2170 Locations: Childrens Hospital Colorado; University of Colorado Hospital |
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Appetite Regulation in Older-Aged Obese Individuals
Participants needed for a research study that plans to examine the effects of age and body weight on food intake, appetite regulation, and brain responses to food....more > Protocol #: 15-1511 Location: University of Colorado Hospital |
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Tissue-specific effects of insufficient sleep
The proposed project is a within-subject consecutive design examining 14 healthy individuals after baseline and after 4 nights of insufficient sleep. Following 7 days of at-home habitual sleep of 9 hours/night and a 3-day lead-in energy balanced diet, participants will be admitted for a 6-...more > Protocol #: 17-0533 Locations: CTRC Inpatient; CTRC-UC Boulder; University of Colorado Hospital |
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The pharmacogenomics of contraception: genetic determinants of etonogestrel pharmacokinetics
? 1 visit lasting 30 minutes ? Visit includes a questionnaire and a blood draw....more > Protocol #: 16-2462 Location: University of Colorado Hospital |
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The impact of estrogen status on the biological function of brown adipose tissue in women measured using quantitative PET/CT
The physiological relevance of brown adipose tissue in humans is largely unknown. We have shown that suppressing ovarian function in premenopausal women reduces resting energy expenditure (REE), and this is prevented by adding back estradiol (E2). Our preliminary data suggest that this may...more > Protocol #: 16-1479 Locations: CTRC-adult; University of Colorado Hospital |