Your search for "Diabetes & Hormone Disorders" found 54 matches:
Does When You Exercise Matter? A Randomized Trial Comparing the Effect of Morning versus Evening Aerobic Exercise on Weight Loss and Compensatory Behaviors

If you join the study, you will undergo screening evaluations to see if you are eligible to be in the study. If you are eligible to be in the study, you will be randomized to one of two study groups. Which group you are assigned to will be chosen by chance by a procedure similar to the t...

Impact of SARS CoV2 on Post-Hospital Recovery of Carbohydrate and Muscle Metabolism: Role of Endothelial Injury
REACH - Role of microvascular insulin resistance and cardiorespiratory fitness in diabetes

CTRC-adult, University of Colorado Hospital

Participants will undergo baseline testing of heart and blood vessel function as well as skeletal muscle function and exercise ability. Participants will then do cardiovascular exercise for 15 weeks, and all testing will be repeated....

Prolonged Sedentary Behavior in Older Women with and without Type 2 Diabetes: Knowledge, Engagement, and Relationship to Cardiometabolic Risk

The purpose of this study is to understand the health effects of the time we spend sitting. We are recruiting women between the ages of 60 and 75 years either with or without a type 2 diabetes diagnosis. Individuals diagnosed with type 2 diabetes may not be treated with insulin in order to...

NightWare Therapeutic Platform for improving Cardiovascular Health in Adults With Nightmares Associated with PTSD

We are recruiting individuals who experience PTSD-associated nightmares to participate in a research study to help us understand if improving sleep quality, by reducing the impact of nightmares can improve cardiovascular health....

MitoQ supplementation for restoring aerobic exercise training effects on endothelial function in postmenopausal women

The purpose of this research study is to see if we can improve exercise training responses on heart health in postmenopausal women....

BURST2D Study: Breaking up sedentary time to improve glucose control in a population at risk for developing type 2 diabetes

The purpose of the study is to compare two different physical activity groups to learn about their effects on blood sugar and metabolism. Participants will be randomly assigned to one of two groups. The first will complete 45-minutes of brisk walking at least 5 days per week and the second...

uHoWL Research Study

Are you interested in a research study on women's reproductive hormones? We are conducting a study among women aged 18-40 who have regular menstrual cycles, are not using hormonal birth control, and have a body mass index between 27-45. ...

PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life - The PROMISE Study

The environment during pregnancy may contribute to the risk of islet autoimmunity (IA) in the baby. Having IA increases the risk of type 1 diabetes (T1D) in the child. Illnesses such as viruses could contribute to IA and T1D risk. Pregnancy history may also influence IA and T1D risk. Ha...

Neuronal and behavioral effects of an implicit priming approach to improve eating behaviors in obesity

What is involved: -A 12-week intervention involving viewing food or food images (study visits once per week) -Study days before and after the intervention to measure brain responses to food images -Measures of body composition, mood, physical activity, and eating behaviors St...

SIB: A Randomized Parallel Comparison of Semaglutide versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus

CTRC-adult

Volunteers needed for a research study examining the effects of once weekly semaglutide on intestinal barrier function in type 2 diabetics who are being treated with metformin only. Main procedures involve blood draws, lactulose mannitol ratio (urine) test, stool samples, and once-weekly s...

The Bone, Exercise, Alendronate, and Caloric Restriction (BEACON) Trial
Integrated Lifestyle Intervention to Promote Weight Loss Study (COMIRB 23-1154)

If you join the study, you will undergo 2-3 screening visits to see if you are eligible to be in the study. If you are eligible to be in the study, you will receive a 6-month integrated lifestyle intervention program. This integrated program includes PreventT2 (formally known as the Diabet...

Effect of weight loss on intermuscular adipose tissue (IMAT) signaling

Following screening visits involving body composition measures, blood testing, strength testing, and a thigh muscle biopsy, participants will go through a 12-week dietary intervention for weight loss. After 12 weeks, this will be followed by the same testing and biopsies that were complete...

Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification

The study is looking for 200 adults diagnosed with T2D within the last 12 months. CU will enroll 100 of those participants. Participants will be assigned to one of two groups. The first group will receive individualized routine care. The second group will receive individualized routine car...

Effects of early as compared to late time restricted eating on weight loss and metabolic outcomes in adults with obesity

Anschutz Health and Wellness, Outpatient CTRC

Single-cell RNA sequencing analysis of thyroid nodule fine needle biopsy aspirate

University of Colorado Hospital

Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults with Obesity

CTRC Inpatient

If you are eligible to be in the study, you will perform baseline measures and then be assigned a randomized sequence of Fasted-AM exercise, Fed-AM exercise, Fasted-PM exercise, Fed-PM exercise. You will complete 5 consecutive days in each of these conditions across a ~5 month timeframe. ...

Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes (T1-DISCO)

Anschutz Health and Wellness, Barbara Davis Center, Brain Imaging Center (BIC), CTRC Inpatient, CU-RIC, Outpatient CTRC, University of Colorado Hospital

Copeptin and Nonalcoholic Fatty Liver Disease

Anschutz Health and Wellness, Outpatient CTRC, UCD Anschutz Health & Wellness Center, University of Colorado Hospital

See above...

JAK Inhibitors to Preserve C-Peptide Production in New Onset T1D: A Phase 2 Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subtype-Selective JAK Inhibitors for Preservation of Pancreatic β Cell Function in Newly Diagnosed Type 1 Diabetes Mellitus

Barbara Davis Center, University of Colorado Hospital

This phase 2 trial is a double-blind, randomized, placebo-controlled clinical trial in male and female adolescent and adult participants (ages 12-35 years) with newly diagnosed Stage 3 T1D (within 100 days of diagnosis). Enrollment into abrocitinib and ritlecitinib arms and the shared ...

Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults with Overweight/Obesity

Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

In this study, we will be evaluating the effects of a reverse-diet compared to standard weight loss maintenance advice....

Expanded Access Program of Palopegteriparatide in Patients with Hypoparathyroidism

University of Colorado Hospital

Intermuscular adipose tissue (IMAT) - protagonist in sarcopenia and insulin resistance in humans

Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Metabolic and Renal Effects of Automated Insulin Delivery Systems in Youth with Type 1 Diabetes Mellitus

Childrens Hospital Colorado

The Neural Underpinnings of Disinhibited Eating Behavior in Adolescents with and without Obesity

Brain Imaging Center - BIC, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Role of semaglutide in restoring ovulation in youth and adults with polycystic ovary syndrome (PCOS) (RESTORE Study)

Childrens Hospital Colorado, Outpatient CTRC

For this study, participants will complete a screening visit to determine eligibility. They will collect 4-months of daily urine to determine rates of ovulation prior to starting semaglutide treatment. They will complete an oral sugar tolerance test (drink a sugary drink) to measure their ...

Adjunctive Anti-Obesity Pharmacotherapy in Adolescents and Young Adults after Bariatric Surgery: A Randomized Controlled Pilot Study

Childrens Hospital Colorado, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

Surgical or Medical Treatment for Pediatric Type 2 Diabetes

Childrens Hospital Colorado, University of Colorado Hospital

Surgical or Medical Treatment for Pediatric Type 2 Diabetes (STOMP-T2D) is a prospective, open-label, controlled clinical trial funded by the National Institutes of Health for a period of 5 years. We propose to study 90 participants who are 13-19 years of age and have type 2 diabetes (T2D)...

Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents

Children's Hospital National (CHN), Children's Hospital National (CHN), Childrens Hospital Colorado, Colorado State University, Uniformed Services University of Health Sciences (USUHS), Uniformed Services University of Health Sciences (USUHS)

Multicentric Carpotarsal Osteolysis (MCTO): Natural History Study

Childrens Hospital Colorado

REMODEL - Renal mode of action of semaglutide in patients with type 2 diabetes and chronic kidney disease

Barbara Davis Center, Childrens Hospital Colorado, Outpatient CTRC, University of Colorado Hospital

Evaluating the peripheral vascular blood flow and oxygenation responses to exercise in type 2 diabetes with time-resolved, quantitative MRI

Brain Imaging Center (BIC), Outpatient CTRC, University of Colorado Hospital

MANATEE-T1D: Metformin ANd AutomaTEd insulin delivery system Effects on renal vascular resistance, insulin sensitivity, and cardiometabolic function in youth with Type 1 Diabetes

Barbara Davis Center, Childrens Hospital Colorado

Identifying novel therapeutic targets in MCTO by unbiased proteomics of patient plasma

Childrens Hospital Colorado, Department Specific Free Standing Clinic

Glucose Monitoring in Youth with Cystic Fibrosis During Pulmonary Exacerbations (GeM-PEx)

Childrens Hospital Colorado

The purpose of this study is to determine if pulmonary exacerbations in youth with cystic fibrosis cause blood sugars to vary during and after an exacerbation. Blood sugars will be monitored using a continuous glucose monitor (CGM) for 2 weeks both during and 6 weeks after an exacerbation...

CLINICAL AND RADIOLOGICAL CHARACTERISTICS OF HYPOPHOSPHATASIA IN ADULTS WITH TYPE 1 DIABETES

Childrens Hospital Colorado, University of Colorado Hospital

Effects of SGLT2 inhibition on early diabetic kidney disease: interrogation of renal energetics by functional imaging and single-cell transcriptomics- an ancillary study to the ATTEMPT trial (COMIRB #19-2947)

Childrens Hospital Colorado

GALAXY: Generating Advancements through Longitudinal Analysis in X and Y Syndromes

Childrens Hospital Colorado, Outpatient CTRC

Participants who join the GALAXY Registry are agreeing to have their medical records be used for research. There are no additional study visits, etc. – participants just continue with their usual clinical care. If participants are seen outside of Children’s Colorado, they can sign a Releas...

Autosomal Dominant Hypocalcemia Types 1 And 2 (ADH1/2) Disease Monitoring Study (DMS)

Childrens Hospital Colorado

Pathogenesis of kidney disease in type 1 diabetes: a modern kidney biopsy cohort (The PANDA Study)

Childrens Hospital Colorado, Outpatient CTRC

Molecular Mechanisms of SGLT2 inhibition in diabetic kidney disease

Brain Imaging Center (BIC), Outpatient CTRC, University of Colorado Hospital

Effect of Montelukast on Kidney and Vascular Function in Type 1 Diabetes

Outpatient CTRC, University of Colorado Hospital

DiEtary Sodium Intake effects on ertugliflozin-induced changes in GFR, reNal oxygenation and systemic hemodynamics: the DESIGN study, a randomized, placebo-controlled, cross-over study with ertugliflozin in people with type 2 diabetes

Outpatient CTRC, University of Colorado Hospital

If you choose to participate, you will take the study medication, ertugliflozin, or placebo over 4 so-called treatment blocks of 20 days each. You will be recommended foods based on a sodium-controlled diet for approximately 23 weeks. There will be 5 study visits total over 23 weeks, which...

TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes

Barbara Davis Center, University of Colorado Hospital

This study will be a multicenter, double-blind, placebo-controlled, 2:1 random assigned, phase II clinical trial for individuals with recent onset type 1 diabetes. We are conducting a double masked placebo-controlled intention to treat study enrolling persons with new onset T1D with docu...

Evaluation of Basal Insulin Initialization and Titration in People with Type 2 Diabetes wearing a Dexcom G6 Sensor

Anschutz Health and Wellness, Lone Tree Medical Center

Effects of Inspiratory muscle strength training on exercise capacity in Type 2 Diabetes

Outpatient CTRC

Expanded Access Program of Palopegteriparatide in Patients with Hypoparathyroidism

Greeley Campus

CALIBRATE: A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Encaleret Compared to Standard of Care in Participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1)

Childrens Hospital Colorado

Open-Label Study Evaluating the Efficacy and Safety of Encaleret Compared to Standard of Care in Participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1)...

Medullary Thyroid Carcinoma & Multiple Endocrine Neoplasia Type 2 Registry

University of Colorado Hospital

Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults with Prediabetes

Anschutz Health and Wellness, Outpatient CTRC

Baseline (no exercise) will be performed first with testing done on the fourth day of this condition. Testing will include a full day at the Anschutz Health Science Building Clinical and Translational Research Core clinic and will involve direct measurements of insulin action on the body, ...

A multi-national, multi-centre, prospective, single-arm, observational, non-interventional post-authorisation safety study to investigate long-term safety of Sogroya? (somapacitan) in adults with growth hormone deficiency (AGHD) under normal routine practice (REAL 7)

University of Colorado Hospital

We are doing this study to collect information about how safe and effective Sogroya ? (somapacitan) is, when used for treatment of people with Adult Growth Hormone Deficiency (AGHD) such as yourself. Sogroya ? (somapacitan), which is prescribed to you by your doctor. It is commercially ava...

Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized, open-label, cross-over trial

Childrens Hospital Colorado

This research is being done to better understand Cystic-Fibrosis Related Diabetes (CFRD) and to see the effects of GLP-1 (dulaglutide) in individuals with abnormal glucose tolerance. GLP-1 (dulaglutide) helps the pancreas release insulin, which controls blood sugar levels from getting too...

BEGIN Substudy: Continuous Glucose Monitoring in Healthy Children

Childrens Hospital Colorado

This data is being collected as a sub-study of a larger study, which is looking at blood sugars in children with Cystic Fibrosis (CF). A device called a continuous glucose monitor (CGM) will be used to collect data for this study. The device brand is the Dexcom G6 and it is an FDA-approv...