Stressful Perceived Experiences on RNA in Men (SPERM) Study
CU Anschutz non-hospital research facilities Participation involves 1 in-person visit per month for 9 months at the Anschutz Medical Campus in Aurora, CO. The study visits include clinical assessments/questionnaires, and provision of semen and urine samples at select visits.... |
Establishing the Efficacy of Parent Management Training for Irritability
Childrens Hospital Colorado Children ages 10-14 will complete an assessment with a licensed mental health professional to determine diagnosis, IQ and behavior at baseline. Parents will complete 12 sessions of parent management training for irritability. The child will be re-assessed in the middle and at the end of t... |
Schacht Research Study 19-1658
Department Specific Free Standing Clinic, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital Few medications are currently Food & Drug Administration (FDA)-approved for the treatment of Alcohol Use Disorder (AUD), and those that are have, on average, modest effects on drinking. Precision medicine research has explored whether patient-level variables, such as genetic variation, may... |
Schacht Research Study 19-2335
Brain Imaging Center (BIC), Department Specific Free Standing Clinic, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital This study evaluates the effects of an FDA-approved medication called tolcapone in people who have both Alcohol Use Disorder (AUD) and Attention-Deficit/Hyperactivity Disorder (ADHD). The study involves seven visits over a three to four week period, including an assessment visit and tw... |
Deep Brain Stimulation (DBS) for Methamphetamine Use Disorder
Brain Imaging Center (BIC), University of Colorado Hospital In a randomized cross-over design of DBS of the nucleus accumbens (NAc) for treatment refractory methamphetamine use disorder (MUD, n=5), we will test safety, feasibility, effect on clinical outcomes (craving and use), and seek to identify biological targets (using cue craving during recor... |
Contraceptive Hormone and Reward Measurement (CHARM Study)
Brain Imaging Center (BIC), Outpatient CTRC, Outpatient CTRC The study is looking at the effects of birth control pills on brain processes and emotional wellbeing. During the study you will be asked to take a birth control pill or a placebo pill (a sugar pill) for 21 days. You won't know which pill you are taking. Birth control is a medication t... |
Group Cognitive Behavioral Treatment for Anxiety in Adolescents with Autism and Intellectual Disability: A Randomized Controlled Trial
Department Specific Free Standing Clinic What is the study about? This study investigates an adapted Cognitive Behavior Therapy (CBT) group treatment to determine if it is more effective than therapy services that adolescents with Autism (ASD) and Intellectual Disability (ID) are already receiving. What does the study entail? ... |
Teen Brain Imaging Study on Irritability and Social Information Processing
Brain Imaging Center (BIC), Brain Imaging Center (BIC) - Scan Read Interested in how irritability affects how teens interpret social situations? Our goal is to learn more about how teens think and feel about unclear social situations and how irritable mood may relate to negative thoughts and feelings about these social situations.... |
Feasibility of VR Programs for Anxiety Related Disorders in an Outpatient Care Setting
Department Specific Free Standing Clinic For this project, semi-structured interviews will be conducted with up to 10 providers specializing in mental health care for adolescents and up to 20 adolescents, ages 14-18, with mild to moderate social anxiety symptoms. Adolescent interviews will focus on using the VR program and provi... |
The Child Bipolar Disorder Network (CBN): A Collaborative Treatment Study of Youth With or at High Risk for Bipolar Disorder
Department Specific Free Standing Clinic, Johnson Depression Center, Outpatient CTRC Does your child have symptoms of bipolar disorder? We are looking for children, teens, and young adults (ages 9 to 21 years) who have moods that alternate between depression and periods of excessive energy and activity for this study. Participants will get a full diagnostic evaluation fro... |
Effects of THC on Alcohol Consumption and Brain Function
Brain Imaging Center (BIC), Outpatient CTRC Alcohol and cannabis are often used together such that their effects overlap. Cannabis edibles (which may contain large doses of THC) have not been well-studied in the laboratory, and it is unclear how such products may impact alcohol consumption patterns. This study will test the effects ... |
Effects of psilocybin with psychological support on anhedonia in treatment-resistant depression
Brain Imaging Center (BIC), Outpatient CTRC Participants will be randomly assigned to receive either active psilocybin or placebo. Participation in the study will last a minimum of 13 weeks, up to a maximum of 26 weeks. The study will involve completion of a physical exam, blood draw, two MRI scans, surveys and psychological assessm... |
Mothers Optimizing Resources Everyday (MORE)
University of Colorado Hospital This study plans to learn more about perinatal mood disorders and sources of support for pregnant and postpartum individuals. Personal and social resources can help individuals cope with the demands associated with the transition to motherhood. Interventions that support personal resources... |
Randomized, controlled trial of Rybelsus (semaglutide) among adults with AUD
Outpatient CTRC, University of Colorado Hospital You will be randomly assigned to one of two groups. You will have a 50% (1 in 2) chance of receiving semaglutide and a 50% chance of receiving placebo. This is a double-blind study, which means neither you nor the study investigator will make the choice to which group you are assigned, an... |
Cannabidiol and Cannabis Concentrate Users: A Randomized, Placebo Controlled Study
Outpatient CTRC, University of Colorado Hospital Study participation will include 4 visits over about 5 weeks, with an on-campus screening visit and three home-based visits in our mobile pharmacology lab, a specially equipped van. Participation will involve taking cannabidiol (CBD) or a placebo.... |
A Study Evaluating the Safety and Effectiveness of RE104, a Psilocybin-like substance, in the Treatment of Patients with Postpartum Depression (PPD)
Department Specific Free Standing Clinic, Outpatient CTRC, University of Colorado Hospital After having a baby, some women get the "baby blues" or feel sad, worried or tired within a few days of giving birth. For many women, the baby blues go away in a few days. However, if any of the following symptoms persist for more than two weeks, this may be a sign of postpartum depressi... |