To join this study, you must first agree to be part of the Prostate Cancer Consortium. This is a patient registry, which is a list of people who have prostate cancer. A patient registry is a place where health data is gathered and stored for research. Being in the registry means you agree to let researchers review your health records and use your data for research without extra doctor visits. You also agree to be contacted about future research studies. The patient registry and any future studies will use information and tools already available in your medical record for the study. These studies are called electronic medical record embedded studies. If you qualify, you would be able to join this study about whether lifestyle changes and a medicine called metformin can help men with prostate cancer improve their metabolic health. To join, log in to your MyHealthConnection account and look under “Research Opportunities”. If you qualify, you’ll see a consent form to sign up. If you decide to join, you will be placed in one of two groups. You won’t get to choose what group – it’s like flipping a coin. One group will get educational materials and email updates about lifestyle changes. The other group will get the same educational materials and email updates and take metformin twice a day. Metformin is a medicine approved to lower blood sugar in people with diabetes and to prevent diabetes in people with prediabetes. It works by reducing the amount of sugar made by the liver. If you join this study, you will still see your cancer doctor. Your doctor will take a blood sample once a year to check your prostate cancer and metabolic health.

10 years