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Solid foods and infant growth
Your baby may be eligible if they are: - Exclusively breastfed - Younger than six months of age - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every month. The first visit, 9-month visit, an... Protocol #19-0546 |
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Blueberry intake and infant gut health
Your breastfed baby may be eligible if they are: - Younger than six months of age - Exclusively breastfed - Full term (> 37-weeks’ gestation) - Have not yet been introduced to solid foods This is a 7-month long study, with visits occurring once every other month. The first and last ... Protocol #20-1659 |
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Early iron exposure on the gut microbiota in young infants
This is a four month-long study, beginning at birth. The first study visit is conducted at the University of Colorado Hospital and the last visit takes place at Children’s Hospital Colorado. The other four visits are conducted in your home. Formula is provided to all study participants for... Protocol #18-1317 |
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Does When You Exercise Matter? A Randomized Trial Comparing the Effect of Morning versus Evening Aerobic Exercise on Weight Loss and Compensatory Behaviors
If you join the study, you will undergo screening evaluations to see if you are eligible to be in the study. If you are eligible to be in the study, you will be randomized to one of two study groups. Which group you are assigned to will be chosen by chance by a procedure similar to the t... Protocol #21-3094 |
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REACH - Role of microvascular insulin resistance and cardiorespiratory fitness in diabetes
Participants will undergo baseline testing of heart and blood vessel function as well as skeletal muscle function and exercise ability. Participants will then do cardiovascular exercise for 15 weeks, and all testing will be repeated.... Protocol #20-2723 |
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The short-chain fatty acid acetate for improving age-associated arterial dysfunction
Specific Aim: To determine the following before and after 12 weeks of oral supplementation with calcium acetate vs. placebo (calcium citrate) in healthy men and women 50+ years of age: a) Endothelium-dependent dilation, assessed as brachial artery flow-mediated dilation (FMDBA) [primary o... Protocol #22-0473 |
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BURST2D Study: Breaking up sedentary time to improve glucose control in a population at risk for developing type 2 diabetes
The purpose of the study is to compare two different physical activity groups to learn about their effects on blood sugar and metabolism. Participants will be randomly assigned to one of two groups. The first will complete 45-minutes of brisk walking at least 5 days per week and the second... Protocol #20-1900 |
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Neuronal and behavioral effects of an implicit priming approach to improve eating behaviors in obesity
What is involved: -A 12-week intervention involving viewing food or food images (study visits once per week) -Study days before and after the intervention to measure brain responses to food images -Measures of body composition, mood, physical activity, and eating behaviors St... Protocol #20-2821 |
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Integrated Lifestyle Intervention to Promote Weight Loss Study (COMIRB 23-1154)
If you join the study, you will undergo 2-3 screening visits to see if you are eligible to be in the study. If you are eligible to be in the study, you will receive a 6-month integrated lifestyle intervention program. This integrated program includes PreventT2 (formally known as the Diabet... Protocol #23-1154 |
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BfedBwell cancer survivorship nutrition program: proof-of-concept pilot study
Cancer survivors who have completed active treatment within the last five years and who have BMI 25-45 kg/m2 will take part in a 12-week study of the BfedBwell survivorship nutrition program. BfedBwell includes group nutrition education and discussion, skills development sessions and cooki... Protocol #23-1501 Location: Colorado Research Center, CTRC-adult, CU Anschutz non-hospital research facilities |
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Effect of weight loss on intermuscular adipose tissue (IMAT) signaling
Following screening visits involving body composition measures, blood testing, strength testing, and a thigh muscle biopsy, participants will go through a 12-week dietary intervention for weight loss. After 12 weeks, this will be followed by the same testing and biopsies that were complete... Protocol #23-0545 |
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Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults with Obesity
If you are eligible to be in the study, you will perform baseline measures and then be assigned a randomized sequence of Fasted-AM exercise, Fed-AM exercise, Fasted-PM exercise, Fed-PM exercise. You will complete 5 consecutive days in each of these conditions across a ~5 month timeframe. ... Protocol #23-1388 Location: CTRC Inpatient |
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Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults with Overweight/Obesity
In this study, we will be evaluating the effects of a reverse-diet compared to standard weight loss maintenance advice.... Protocol #17-1726 Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital |
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Surgical or Medical Treatment for Pediatric Type 2 Diabetes
Surgical or Medical Treatment for Pediatric Type 2 Diabetes (STOMP-T2D) is a prospective, open-label, controlled clinical trial funded by the National Institutes of Health for a period of 5 years. We propose to study 90 participants who are 13-19 years of age and have type 2 diabetes (T2D)... Protocol #19-1978 Location: Childrens Hospital Colorado, University of Colorado Hospital |
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Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents
Protocol #20-2649 Location: Children's Hospital National (CHN), Children's Hospital National (CHN), Childrens Hospital Colorado, Colorado State University, Uniformed Services University of Health Sciences (USUHS), Uniformed Services University of Health Sciences (USUHS) |
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Harnessing Cells from Human Milk; Linking Lactation to Metabolism
In this study: - Participants will complete 2 study visits (in late pregnancy & 2 wks postpartum) - Participants will have their milk production measured and provide blood and breastmilk samples If you join the study, you will be part of the study for up to a month and a half, lasting... Protocol #21-2835 Location: CTRC Inpatient, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital |
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Menstrual profiles and cardiovascular disease risk among female adolescent athletes with and without menstrual irregularities
Participants will undergo a bone scan, 15 minutes of metabolic testing, and blood draw to assess markers of cardiovascular disease as well as hormone levels. ... Protocol #22-1372 Location: Childrens Hospital Colorado, Department Specific Free Standing Clinic, Outpatient CTRC |
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A single and repeat dosing study of the safety, drug exposure, and clinical activity of R-3750 in patients with mild to moderate ulcerative colitis
A single and repeat dosing study of the safety, drug exposure, and clinical activity of R-3750 in patients with mild to moderate ulcerative colitis... Protocol #23-0025 Location: Outpatient CTRC, University of Colorado Hospital |
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Boomerang Early Feasibility Study: Prospective, multi-center, single-arm early feasibility study (EFS)
Researchers in the BOOM-IBD Clinical Trial are studying whether nerve stimulation can be effective in treating patients with Crohn's disease and ulcerative colitis.... Protocol #23-0063 Location: Outpatient CTRC, University of Colorado Hospital |
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Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study)
This study plans to investigate if taking a protein nutrition supplement (EAA) for 8 weeks may reduce fat that is stored in the liver. This will be compared to 8 weeks of placebo (a “fake” supplement that does not contain protein). Participants will be assigned randomly either the protein ... Protocol #23-0690 Location: Brain Imaging Center (BIC), Brain Imaging Center - BIC, Childrens Hospital Colorado, Outpatient CTRC, University of Colorado Hospital |