|
Early iron exposure on the gut microbiota in young infants
This is a four month-long study, beginning at birth. The first study visit is conducted at the University of Colorado Hospital and the last visit takes place at Children’s Hospital Colorado. The other four visits are conducted in your home. Formula is provided to all study participants for... |
|
Relationship between Cardiac Health and Exercise Capacity in Men and Women with and without Type 2 Diabetes
CTRC-adult, University of Colorado Hospital Participants will undergo baseline testing of their heart, blood vessel, and skeletal muscle function, and perform tests to determine exercise ability. Participants will then do exercise training for 15 weeks, and all testing will be repeated.... |
|
The short-chain fatty acid acetate for improving age-associated arterial dysfunction
If you join this study, you will participate in Screening, Baseline, Study Period, and End of Study visits over a ~4-month period. These visits will take about 14 hours of your time total. The study visits will take place at the Division of Renal Diseases and Hypertension Clinical Research... |
|
BURST2D Study: Breaking up sedentary time to improve glucose control in a population at risk for developing type 2 diabetes
The purpose of the study is to compare two different physical activity groups to learn about their effects on blood sugar and metabolism. Participants will be randomly assigned to one of two groups. The first will complete 45-minutes of brisk walking at least 5 days per week and the second... |
|
Volunteers needed for research study on changing eating behaviors
Study volunteers will be asked to complete an MRI scan, during which they will watch pictures of foods. Participants will also complete a 12-week intervention that involves viewing food or food images, with once-weekly study visits. After the intervention, we will ask volunteers to complet... |
|
Integrated Lifestyle Intervention to Promote Weight Loss Study (COMIRB 23-1154)
If you join the study, you will undergo 2-3 screening visits to see if you are eligible to be in the study. If you are eligible to be in the study, you will receive a 6-month integrated lifestyle intervention program. This integrated program includes PreventT2 (formally known as the Diabet... |
|
Effect of weight loss on intermuscular adipose tissue (IMAT) signaling
Following screening visits involving body composition measures, blood testing, strength testing, and a thigh muscle biopsy, participants will go through a 12-week dietary intervention for weight loss. After 12 weeks, this will be followed by the same testing and biopsies that were complete... |
|
A Study Evaluating an Intermittent Fasting Intervention in Adults with Breast Cancer and Overweight or Obesity
If you decide to participate in the study, you will be on an intermittent fasting diet three days per week to reduce what you are eating for 6 months. On the intermittent fasting diet days, you will only eat about 500 calories per day. On the other four non-fasting diet days per week, you ... |
|
How When you Eat and Exercise Affect Metabolism in Adults
As a participant in this study, you will be assigned to 4 different diet and exercise groups where the time of your meals and when you exercise will be different. This will last for 4 consecutive days, and you will be provided meals on 2-3 of the days. On the 5th day of each exercise and d... |
|
Surgical or Medical Treatment for Pediatric Type 2 Diabetes
Childrens Hospital Colorado, University of Colorado Hospital Surgical or Medical Treatment for Pediatric Type 2 Diabetes (STOMP-T2D) is a prospective, open-label, controlled clinical trial funded by the National Institutes of Health for a period of 5 years. We propose to study 90 participants who are 13-19 years of age and have type 2 diabetes (T2D)... |
|
Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents
Children's Hospital National (CHN), Children's Hospital National (CHN), Childrens Hospital Colorado, Colorado State University, Uniformed Services University of Health Sciences (USUHS), Uniformed Services University of Health Sciences (USUHS) |
|
Harnessing Cells from Human Milk; Linking Lactation to Metabolism
CTRC Inpatient, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital In this study: - Participants will complete 2 study visits (in late pregnancy & 2 wks postpartum) - Participants will have their milk production measured and provide blood and breastmilk samples If you join the study, you will be part of the study for up to a month and a half, lasting... |
|
Menstrual profiles and cardiovascular disease risk among female adolescent athletes with and without menstrual irregularities
Childrens Hospital Colorado, Department Specific Free Standing Clinic, Outpatient CTRC Participants will undergo a bone scan, 15 minutes of metabolic testing, and blood draw to assess markers of cardiovascular disease as well as hormone levels. ... |
|
A single and repeat dosing study of the safety, drug exposure, and clinical activity of R-3750 in patients with mild to moderate ulcerative colitis
Outpatient CTRC, University of Colorado Hospital A single and repeat dosing study of the safety, drug exposure, and clinical activity of R-3750 in patients with mild to moderate ulcerative colitis... |
|
Boomerang Early Feasibility Study: Prospective, multi-center, single-arm early feasibility study (EFS)
Outpatient CTRC, University of Colorado Hospital Researchers in the BOOM-IBD Clinical Trial are studying whether nerve stimulation can be effective in treating patients with Crohn's disease and ulcerative colitis.... |
|
Effect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study)
Brain Imaging Center (BIC), Brain Imaging Center (BIC) - Scan Read, Childrens Hospital Colorado, Outpatient CTRC, University of Colorado Hospital This study plans to investigate if taking a protein nutrition supplement (EAA) for 8 weeks may reduce fat that is stored in the liver. This will be compared to 8 weeks of placebo (a “fake” supplement that does not contain protein). Participants will be assigned randomly either the protein ... |
|
Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults with Prediabetes
Anschutz Health and Wellness, Outpatient CTRC Baseline (no exercise) will be performed first with testing done on the fourth day of this condition. Testing will include a full day at the Anschutz Health Science Building Clinical and Translational Research Core clinic and will involve direct measurements of insulin action on the body, ... |
|
A multi-national, multi-centre, prospective, single-arm, observational, non-interventional post-authorisation safety study to investigate long-term safety of Sogroya? (somapacitan) in adults with growth hormone deficiency (AGHD) under normal routine practice (REAL 7)
University of Colorado Hospital We are doing this study to collect information about how safe and effective Sogroya ? (somapacitan) is, when used for treatment of people with Adult Growth Hormone Deficiency (AGHD) such as yourself. Sogroya ? (somapacitan), which is prescribed to you by your doctor. It is commercially ava... |
|
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program to
Evaluate the Efficacy and Safety of MK-7240 in Participants with Moderately to Severely
Active Ulcerative Colitis
Outpatient CTRC, University of Colorado Hospital A phase three study to evaluate the safety and tolerability of MK-7240 for patients who have moderate to severely active ulcerative colitis (UC). ... |