This study wants to find better treatments for people with autoimmune diseases like rheumatoid arthritis (RA). By studying the different types of cells found in people with RA, researchers can learn more about how RA damages joints.
To evaluate the efficacy of IMVT-1402 compared to placebo in participants with CLE as assessed by changes in the Cutaneous Lupus Erythematosus Disease area and Severity Index activity (CLASI-A) score
This study aims to evaluate the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult participants with cutaneous lupus erythematosus (CLE)
Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus
We want to find out how well the medicine Belimumab works in real life for adults who have active lupus nephritis. This study also wants to see if belimumab helps keep the kidneys healthy for a long time.
We are looking for adults to join a national study to help us learn more about how rheumatoid arthritis (RA) develops.
This study wants to learn more about people who get a treatment called Genicular Artery Embolization (GAE). GAE is a procedure to help adults with long-term knee pain feel better. This study will look at changes in the fluid in your knee, pictures of your knee (MRI), and how well you move before and after the treatment.
This study is testing a new drug called SC291 to see if it is safe and if it can help treat serious autoimmune diseases that have come back or stopped responding to treatment.
To evaluate the efficacy of GS-5718 versus placebo-to-match (PTM) in reducing skin disease activity for participants with CLE with or without systemic lupus erythematosus. To evaluate the efficacy of GS-5718 versus PTM in reducing skin disease activity f
For Period 1, the primary objective is to evaluate the efficacy and safety of upadacitinib and adalimumab, in adult subjects on background MTX, following an inadequate response or intolerance to a single TNFi. For Period 2, the objective is to evaluate th
In this study, we plan to learn about the causes of rheumatoid arthritis (RA) and about lung disease in RA. RA is an autoimmune disease that can cause arthritis, and in some people, RA can also be related to lung disease called ‘interstitial lung dis
This study aims to understand how topical cannabis products (creams, salves, balms, etc.) could help relieve the symptoms of joint pain.
To evaluate the safety and effectiveness of the Spinal Kinetics M6-C™ artificial cervical disc in patients with contiguous twolevel symptomatic cervical radiculopathy with or without cord compression.
To evaluate the efficacy of VIB4920 antoagonism of CD40L in achieving a complete renal response in active lupus nephritis
To learn more about lung disease and risk of lung disease in early RA.
This study involves chimeric antigen receptor (CAR) T cell therapy, which is a relatively new therapeutic approach that uses a patient's own immune cells to treat their disease. In autoimmune diseases such as rheumatoid arthritis (RA), certain parts of th
The primary objective of the current study is to validate the performance of the current ASAS classification criteria in a prospective, combined cohort of patients presenting with undiagnosed current back pain.
The primary objective of this study is to demonstrate efficacy of BIIB059 compared with placebo in participants with active systemic lupus erythematosus (SLE), who are receiving background lupus standard of care (SOC) therapy in reducing disease activity.
To fully characterize safety and efficacy when the coflex® device is used in the intended subject population under the actual conditions of use”
To longitudinally study individuals at risk for spondyloarthritis and spondyloarthritis associated diseases.
Primary objective is to evaluate the effectiveness of cenerimod 4mg at reducing disease activity compared to placebo. The secondary objective is to evaluate the effect of cenerimod 4mg to control the disease compared to placebo. The safety objective is to
To evaluate the safety and tolerability of benralizumab
Use of blood flow restriction cuffs in post surgical hip patients.
This study wants to learn about how total joint replacements affect the lives and physical abilities of children and young adults as they grow older.
This study wants to learn which physical therapy treatments are most helpful to individuals with chronic neck pain including parts of treatment outside of the treatment itself such as the patient and therapist relationship. The study will compare two different treatments, resistance exercise and manual therapy. Resistance exercise builds muscle strength by making your muscles work against a weight...