Find a Research Study

Find a Research Study

Find a Research Study

Find a Research Study

Find a Research Study

A Study to See How Belimumab Works in Everyday Care for Adults with Lupus Nephritis

We want to find out how well the medicine Belimumab works in real life for adults who have active lupus nephritis. This study also wants to see if belimumab helps keep the kidneys healthy for a long time.


Why this Research Matters

If you qualify and want to join this study, you will go to the clinic for your regular doctor visits. No extra visits are needed. On these visits, we will collect information from your medical records. This includes your year of birth, gender, race and ethnicity, if you smoke, your medical history like lupus nephritis diagnosis and biopsy results, treatments you had for lupus nephritis, other medicines you take, other health problems, blood pressure, height, weight, hospital stays, and blood test results. We will collect this information from up to 12 months before you started belimumab (and biopsy results from up to 24 months before), when you started belimumab, and then every 6 months at your regular visits for up to 48 months. We will also collect data at your 5-year (60-month) visit. You will be asked to do two short surveys about your tiredness and how lupus affects your life. You will take these surveys when you join, then every 6 months up to 24 months, and then once a year until 5 years after starting belimumab. Each survey takes about 15 minutes and will be done on a tablet given by the study staff. You will get $25 for each survey you finish. You can get paid for up to seven surveys, or $175 total, after the study staff checks that you completed them.


Who can Participate

Adult

Adults who have lupus nephritis and are taking or planning to start belimumab can join this study. You must be 18 years or older when you start belimumab. You must have started belimumab between 6 and 24 months before joining the study. You must have medical records from when you started belimumab, including records from 12 months before starting and a kidney biopsy from 24 months before starting belimumab. You must have a biopsy that shows active lupus nephritis in the two years before starting belimumab. This includes Class III (focal LN) with or without Class V (membranous LN), Class IV (diffuse LN) with or without Class V, or Class V. If you are pregnant or plan to become pregnant, please tell your study doctor. You may not be able to join the study. Also, tell the study staff if you are in another research study. You cannot join if the other study tests a drug. But you may join if the other study does not test a drug.


Study ID

Protocol Number: 24-1879


Compensation Information

Compensation
Study Payment: Compensation provided.

Meet the Team

Image of Principal Investigator

Amber Podoll, MD

Principal Investigator