ALLFTD: ARTFL-LEFFTDS LONGITUDINAL FRONTOTEMPORAL LOBAR DEGENERATION
Protocol #: 21-2833
Locations: Brain Imaging Center (BIC); Outpatient CTRC; University of Colorado Hospital
|
THE EVALUATION OF IMMUNE RESPONSES TO SARS-COV-2 MRNA VACCINES IN MULTIPLE SCLEROSIS PATIENTS ON OCRELIZUMAB
Protocol #: 21-3126
Locations: Outpatient CTRC; University of Colorado Hospital
|
Persistent Abnormal Cerebrovascular Reactivity and Vessel Wall Enhancement in Individuals Recovered from COVID-19 Infection
Protocol #: 21-2881
Location: University of Colorado Hospital
|
Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS Study
Protocol #: 20-2772
Location: University of Colorado Hospital
|
Sleep assessed by actigraphy and direct recordings of the subthalamic nucleus in Parkinson's Disease.
Protocol #: 20-2508
Locations: Lone Tree Medical Center; University of Colorado Hospital
|
Cerebrospinal fluid-biomarkers-based diagnostic and prognostic models for multiple sclerosis (SPINCOMS)
Protocol #: 20-1025
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
A Phase 3b, Multicenter, Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Oral Edaravone Administered for a Period of 48 Weeks in Subjects with Amyotrophic Lateral Sclerosis (ALS)
Protocol #: 20-2340
Location: University of Colorado Hospital
|
A single-arm, prospective, multi-center, study to explore maintained efficacy with ofatumumab therapy in patients with relapsing Multiple Sclerosis who discontinue
intravenously delivered anti-CD20 monoclonal antibody (aCD20 mAb) therapy (OLIKOS)
Protocol #: 20-2135
Locations: Brain Imaging Center (BIC); Outpatient CTRC; University of Colorado Hospital
|
A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF FENEBRUTINIB COMPARED WITH TERIFLUNOMIDE IN ADULT PATIENTS WITH RELAPSING MULTIPLE SCLEROSIS
Protocol #: 20-2036
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
A PHASE 2, RANDOMIZED, DOUBLE-BLIND,
PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PEGCETACOPLAN IN SUBJECTS WITH AMYOTROPHIC LATERAL SCLEROSIS (ALS)
Protocol #: 20-2005
Locations: CTRC Inpatient; Outpatient CTRC; University of Colorado Hospital
|
A RANDOMIZED, DOUBLE-BLIND, MULTICENTER, PLACEBO-CONTROLLED PHASE 3 STUDY WITH OPEN-LABEL PERIOD TO EVALUATE THE EFFICACY AND SAFETY OF INEBILIZUMAB IN ADULTS WITH MYASTHENIA GRAVIS
Protocol #: 20-1787
Location: University of Colorado Hospital
|
Genetics of CMT - Modifiers of CMT1A, New Causes of CMT
Protocol #: 20-1525
Location: University of Colorado Hospital
|
A double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of intravenous ganaxolone in status epilepticus
Status Epilepticus is a serious condition that needs fast treatment to stop the seizures and prevent permanent brain damage. Ganaxolone is an investigational drug, which means that it is not approved by the US FDA. The study drug will be added on to the usual care patients will already be ...more >
Protocol #: 20-1641
Location: University of Colorado Hospital
|
Patient Preferences in Deep Brain Stimulation Products
Protocol #: 19-3015
Location: University of Colorado Hospital
|
The Parkinson's Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort
Protocol #: 20-1204
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
A Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide (Aubagio?) in participants with relapsing forms of multiple sclerosis (GEMINI 1)
Protocol #: 20-1101
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
A single-arm, prospective, multicentre, open-label study to evaluate ofatumumab treatment effectiveness and patientreported outcomes in patients with relapsing multiple sclerosis transitioning from dimethyl fumarate or fingolimod therapy (COMB157G23101)
Protocol #: 20-0705
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
A Phase 2, Randomized, Placebo-Controlled Study to Evaluate Safety, Tolerability, and
Efficacy of TAK-079 in Patients With Generalized Myasthenia Gravis
Protocol #: 20-0609
Location: University of Colorado Hospital
|
A Phase 1, Two-part, Open-label Dose-escalation and Double-blind, Placebo-controlled Dose-expansion Study with an Open-label Extension to Evaluate the Safety and Efficacy of ATA188 in Subjects with Progressive Multiple Sclerosis (ATA188-MS-101
Protocol #: 20-0454
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
Deep sleep in Parkinson disease and its relationship to cognition, neuroinflammation and neurodegeneration
Protocol #: 20-0347
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
ALS toolkit project
Protocol #: 20-0127
Location: University of Colorado Hospital
|
Platform Trial for the Treatment of Amyotrophic Lateral Sclerosis (ALS): A perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS.
Protocol #: 19-2645
Location: University of Colorado Hospital
|
Lipoic acid for Treatment of Progressive Multiple Sclerosis
Protocol #: 19-2525
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of 36 Weeks of Treatment with NLY01 in Early-stage Parkinson's Disease
Protocol #: 19-2471
Location: University of Colorado Hospital
|
An Open Label Extension Study of Ublituximab in Subjects with Relapsing Multiple Sclerosis
Protocol #: 19-2378
Locations: Brain Imaging Center (BIC); Outpatient CTRC; University of Colorado Hospital
|
A MULTICENTER, LONGITUDINAL, OPEN-LABEL, SINGLE-ARM STUDY DESCRIBING COGNITIVE PROCESSING SPEED CHANGES IN RELAPSING MULTIPLE SCLEROSIS SUBJECTS TREATED WITH OZANIMOD (RPC-1063)
Protocol #: 19-2420
Locations: Brain Imaging Center (BIC); Outpatient CTRC; University of Colorado Hospital
|
A Room Temperature Atomic Magnetrode System for Telemetry of Epileptic Seizures
Protocol #: 19-2363
Location: University of Colorado Hospital
|
CLadribine Tablets: Collaborative Study to Evaluate the Impact On Central Nervous System BiomarKers in Multiple Sclerosis (CLOCK-MS)
Protocol #: 19-1980
Locations: Brain Imaging Center (BIC); Outpatient CTRC; University of Colorado Hospital
|
A Prospective Study of Acute Flaccid Myelitis (AFM) to Define Natural History, Risk Factors, and Pathogenic Mechanisms
Protocol #: 19-2357
Location: Childrens Hospital Colorado
|
A Phase 3, External Placebo-Controlled, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Patients with Neuromyelitis OpticavSpectrum Disorder (NMOSD)
Protocol #: 19-2038
Locations: Brain Imaging Center (BIC); Outpatient CTRC; University of Colorado Hospital
|
Perceived Palliative Care Needs in Early-Onset Dementia
Protocol #: 19-2134
Locations: Outpatient CTRC; UCHealth Central Park Medical Center; University of Colorado Hospital
|
A Multicenter Randomized Controlled Trial of Best Available Therapy versus Autologous Hematopoietic Stem Cell Transplant for Treatment-Resistant Relapsing Multiple Sclerosis
Protocol #: 19-1621
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
Neurological Screening of Controls in an Age-Related Macular Degeneration Registry
Protocol #: 19-1925
Location: University of Colorado Hospital
|
AN OBSERVATIONAL STUDY OF OCRELIZUMAB TREATED PATIENTS WITH MULTIPLE SCLEROSIS TO DETERMINE THE INCIDENCE AND MORTALITY RATES OF BREAST CANCER AND ALL MALIGNANCIES (VERISMO STUDY)
Protocol #: 19-1600
Location: University of Colorado Hospital
|
A Post-Market Study Evaluating the Safety of Infinity DBS System with MR Conditional Labeling
Protocol #: 19-1566
Location: University of Colorado Hospital
|
GRASP-LGMD RESEARCH PROTOCOL; Project 1a Defining Clinical Endpoints in LGMD
Protocol #: 19-0506
Location: University of Colorado Hospital
|
ImTAB
Immunity, mTBI, and Alzheimer's Biomarkers
You may qualify if you are:
- 65 years or older
- Have had a concussion within the past 5 years
- Saw a doctor within 1 week of your concussion
- Have not been diagnosed with a memory disorder
Participants will receive:
-Snacks and refreshments
-Medical screening (neurological e...more >
Protocol #: 19-1423
Locations: Outpatient CTRC; University of Colorado Hospital
|
GBM AGILE Global Adaptive Trial Master Protocol: An International, Seamless Phase II/III Response Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens In Newly Diagnosed and Recurrent GBM (GCAR-7213)
Protocol #: 19-0744
Location: University of Colorado Hospital
|
Feasibility of the Multiple Sclerosis Performance Test for assessment of functional performance measures in patients with Multiple Sclerosis
Protocol #: 19-1192
Location: University of Colorado Hospital
|
Comparative Effectiveness Research for Infantile Spasms V: 12Jan2017
Protocol #: 16-2408
Location: Childrens Hospital Colorado
|
Neurophysiological Correlates V: 31Jan18
Protocol #: 16-1480
Location: Childrens Hospital Colorado
|
Natural History of Rett Syndrome and Related Disorders
Protocol #: 15-2332
Location: Childrens Hospital Colorado
|
A Two-year Prospective Natural History Study Examining the Use of Neuronal Injury Biomarkers in Autoimmune Encephalitis as a Potential Biomarker for Disease Activity and Severity
Protocol #: 19-0889
Locations: Brain Imaging Center (BIC); Childrens Hospital Colorado; Colorado Research Center; University of Colorado Hospital
|
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3
Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for
Severe Cerebral Edema following Large Hemispheric Infarction
Protocol #: 19-0675
Location: University of Colorado Hospital
|
A Phase I/II Study of Nivolumab Plus or Minus Ipilimumab in Combination with Multi-Fraction Stereotactic Radiosurgery for Recurrent High-Grade Radiation-Relapsed Meningioma
Protocol #: 19-0423
Location: University of Colorado Hospital
|
AMPLATZERTM PFO Occluder Post
Approval Study
This is a single arm, multi-center study to confirm the safety and effectiveness of the AMPLATZERTM PFO Occluder in the post approval setting...more >
Protocol #: 19-6502
Location: Memorial Hospital Central
|
Detection and Risk in Early MS
Protocol #: 19-0393
Locations: Brain Imaging Center (BIC); University of Colorado Hospital
|
A Natural History Study of CMT1B, CMT2A, CMT4A and CMT4C
Protocol #: 18-2537
Location: University of Colorado Hospital
|
GORE? CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients with Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
This study will assess the safety and effectiveness of GORE? CARDIOFORM Septal Occluder in a post approval setting and evaluate the quality of operator education and training and transferability of trial experience to a post-market setting....more >
Protocol #: 19-6030
Locations: Harmony Campus; Medical Center of the Rockies
|
Bedside Resources to Gauge Intravascular Volume Status in Hypovolemic Infants in the Operating Room
Protocol #: 18-2513
Location: Childrens Hospital Colorado
|
Investigating cortical networks disruption and rehabilitation after traumatic brain injury
Protocol #: 19-0049
Locations: Colorado Research Center; Department Specific Free Standing Clinic
|
Gene Expression of Cerebral Aneurysms
In this study, we will collect tissue and blood from participants during their epilepsy surgery. ...more >
Protocol #: 19-0182
Location: University of Colorado Hospital
|
How Does Inflammation Affect the Aging Brain? Research Study Investigates Aging, Memory, and Immune Function.
The University of Colorado Anschutz Medical Campus is looking for interested adults 60 and over to participate in a research study examining how inflammation influences brain health. Data gathered from this study will be used to better understand how inflammation may or may not disrupt thi...more >
Protocol #: 18-2607
Location: University of Colorado Hospital
|
Association of depth recordings from the temporal cortex with sleep pattern detection and characterization of sleep dysfunction in patients with refractory epilepsy.
Protocol #: 18-2806
Location: University of Colorado Hospital
|
Identifying relevant seizure biomarkers from RNS? System recorded electrocorticography for the development of optimized seizure detection algorithms
Protocol #: 18-2089
Location: University of Colorado Hospital
|
Determining the Effectiveness of early Intensive
Versus Escalation approaches for the treatment of Relapsing-Remitting Multiple Sclerosis (DELIVERMS)
Protocol #: 18-1633
Location: University of Colorado Hospital
|
Clinical Outcome Measures in Friedreich's Ataxia
Protocol #: 18-1641
Locations: Outpatient CTRC; University of Colorado Hospital
|
A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy STELLAR Study
Protocol #: 18-1336
Location: University of Colorado Hospital
|
Peripheral Inflammatory Cytokine Levels in Parkinson Disease
Protocol #: 18-1356
Location: University of Colorado Hospital
|
Conversational Speech in the Diagnosis of Neurocognitive Disorders
Protocol #: 18-0456
Locations: Outpatient CTRC; University of Colorado Hospital
|
More than a Movement Disorder: Applying Palliative Care to Parkinson?s Disease v: 12/06/2017
Protocol #: 16-1400
Locations: Colorado Research Center; Department Specific Free Standing Clinic
|
Neurologic Music Therapy for enhancing fine motor control in Parkinson's Disease 16Apr2018
Protocol #: 16-2308
Location: University of Colorado Hospital
|
COG ANBL1531 - A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma (NBL) (IND# 134379)
Protocol #: 18-0971
Location: Childrens Hospital Colorado
|
Ruptured Aneurysms Treated with Hydrogel Coils
Protocol #: 18-6052
Location: Memorial Hospital Central
|
Automatic measurement of hand movements toward development of an objective assessment of primary motor symptoms in Parkinson?s disease
Protocol #: 15-1041
Location: University of Colorado Hospital
|
Diet and Relapses in Pediatric Multiple Sclerosis
Protocol #: 18-0393
Locations: Childrens Hospital Colorado; University of Colorado Hospital
|
Perceived palliative care needs of Huntington's disease patients
Protocol #: 18-0216
Location: University of Colorado Hospital
|
Clinical Trial Readiness for SCA1 and SCA3
Protocol #: 18-0020
Location: University of Colorado Hospital
|
Validation of a performance-based assessment of functional ability related to cognition in Parkinson's disease
Protocol #: 15-0170
Locations: Colorado Research Center; Department Specific Free Standing Clinic; Outpatient CTRC; University of Colorado Hospital
|
Risk factors in Early Multiple Sclerosis (RisE-MS)
Protocol #: 17-1884
Locations: Outpatient CTRC; University of Colorado Hospital
|
A randomized, double blind, placebo-controlled parallel study of tolerability and efficacy of Cannabidiol (CBD) on tremor in Parkinson's disease
Protocol #: 17-2318
Location: University of Colorado Hospital
|
Topiramate as a disease altering therapy for Cryptogenic Sensory Peripheral Neuropathy (CSPN)
Protocol #: 17-1751
Location: University of Colorado Hospital
|
Transcranial electrical stimulation for the treatment of cervical dystonia
Protocol #: 17-1322
Locations: Colorado Research Center; Department Specific Free Standing Clinic
|
Calibrating free-living physical activity characteristics across functionally-limited populations using machine-learned accelerometer approaches
Regular physical activity is known to have positive effects on many health outcomes. In research, physical activity is often measured using activity monitors worn on the hip, wrist or ankle. These instruments determine how much physical activity a person does based on the amount of movemen...more >
Protocol #: 16-2706
Locations: CTRC-adult; University of Colorado Hospital
|
The modified Atkins diet in patients with drug resistant epilepsy and the responsive neurostimulator 09Aug2017
Protocol #: 17-0888
Location: University of Colorado Hospital
|
Using Next Generation Sequencing to Unravel the Pathogenesis of Sporadic Inclusion Body Myositis (IBM) - The International IBM Consortium Genetic Study
Protocol #: 17-1132
Location: University of Colorado Hospital
|
Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE) Study
Protocol #: 17-0873
Locations: Lone Tree Medical Center; University of Colorado Hospital
|
10-1311
DoneSave
Functional connectivity of the motor network in two major subtypes of Parkinson Disease December 24,2015
Protocol #: 10-1311
Location: University of Colorado Hospital
|
Rocky Mountain Multiple Sclerosis Center (RMMSC) Biorepository for the Study of Neuroimmunological Disorders
Protocol #: 12-0968
Location: University of Colorado Hospital
|
University of Colorado Alzheimer's and Cognition Center Longitudinal Biomarker and Clinical Phenotyping Study (Bio-AD Study)
This study will establish a large bank of samples and data for future research into the causes of and treatments for Alzheimer’s disease (AD), Down Syndrome (DS) and other diseases that cause thinking and memory problems....more >
Protocol #: 15-1774
Location: University of Colorado Hospital
|
A Phase IV Trial of Neuroprotection with ACTH in Acute Optic Neuritis
Protocol #: 13-0388
Location: University of Colorado Hospital
|
Wireless electroencephalography for continuous monitoring in the EEG LTM unit 12Apr2018
Protocol #: 15-0449
Location: University of Colorado Hospital
|
NAtalizumab for Prevention of Post-partum Relapses in patients with
Multiple Sclerosis 09May2016
Protocol #: 16-0156
Location: University of Colorado Hospital
|
Collaborative International Research in Clinical and Longitudinal Experience for Neuromyelitis Optica (NMO) Studies
Protocol #: 13-3181
Location: University of Colorado Hospital
|