The objective of this study is to see if executive functioning can be effected by non-invasive vagus nerve stimulation.
To assess the proper amount of dose to give participants and to evaluate the safety of [177Lu]Lu-NeoB (called Lutetium-NeoB) in participants who have just been diagnosed with glioblastoma (our site won't enroll anyone with recurrent glioblastoma). This research study will also assess if an investigational imaging agent, [68Ga]Ga-NeoB (called Gallium-NeoB), is well tolerated and has the ability...
This study will evaluate the effectiveness and safety of risdiplam (Evrysdi®) administered to patients under 2 years of age genetically diagnosed with spinal muscular atrophy (SMA) and 2 SMN2 copies who have previously received onasemnogene abeparvovec.
This study will evaluate the effectiveness and safety of risdiplam (Evrysdi®) administered to patients under 2 years of age genetically diagnosed with spinal muscular atrophy (SMA) and 2 SMN2 copies who have previously received onasemnogene abeparvovec and experience a plateau or decline in function.
Treatment of Duchenne Muscular Dystrophy (DMD) with dystrophin deletion amenable to exon 50 skipping
The goal of this study is to prioritize caregiver perspectives regarding the quality and satisfaction of dementia care their loved one is receiving. Sharing the lived experiences of caregivers gives health care providers an opportunity to better meet the needs of the patient and the caregiver in the future.
To assess the safety and tolerability of EDG-5506 in children with DMD
We are studying teens who feel angry a little, sometimes, or a lot to see if they think about social situations in different ways. Teens who often feel very angry might have more problems when they grow up, so we want to learn more about how their brains work.
This study will measure emotion regulation and brain function using fMRI in healthy adults and adults beginning AUD treatment. The adults being treated will be followed for 6 months after treatment to assess relapse outcomes.
The purpose of this research study is to learn more about the safety and effectiveness of a drug called sargramostim for improving cognitive function and memory in people with Alzheimer’s disease.
To evaluate the safety and tolerability of multiple-ascending dose (MAD) levels, 40 mg/kg, 60 mg/kg, and 80 mg/kg, of NS-089/NCNP-02 in ambulant boys with DMD after 4 weeks of once weekly intravenous (IV) treatment; and o evaluate the pharmacokinetics (PK) of MAD levels of NS-089/NCNP-02.
This study wants to learn how aerobic exercise affects people with Parkinson’s disease who have not started medication for their Parkinson’s symptoms. It will compare two types of treadmill exercise – moderate-intensity and high-intensity – to see how they impact Parkinson’s symptoms.
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple therapies in newly diagnosed (ND) and recurrent GBM
Our study is seeking individuals aged 55-85, who have been diagnosed with Mild Cognitive Impairment (MCI) and are at risk for Alzheimer's Disease. The goal of the study is to see whether cannabidiol (CBD) can improve MCI symptoms.
This study plans to learn more about genes that are expressed in blood vessels in the brain and in the blood of patients without brain aneurysms. This will help us understand diseases that affect those blood vessels such as aneurysms.
This study wants to better understand Down syndrome and the health problems that are more likely to affect people with Down syndrome. To do this, we are collecting blood and saliva samples from people with and without Down syndrome so that they are more accessible for future research studies.
The purpose of this study is to examine the impact of exercise on sleep and cognition in Parkinson’s Disease.
We want to learn how stimulating the vagus nerve while moving the hand can help improve fine motor control in people with relapsing-remitting multiple sclerosis (MS), who have trouble moving their hands and arms.
To study how infants’ ability to differentiate speech sounds develops and how this ability affects other measures of auditory development.
We are looking for teens with autism, ages 13-19, to help us study how exercise and social gaming affect brain responses.
We are studying how sleep affects memory in people with traumatic brain injuries. We need healthy people that do not have any neurological conditions to join our study!
We are looking for adults with a glioma brain tumor (grades 2, 3, or 4) to share their ideas on a new program to improve health and well-being for brain cancer survivors.
We are looking for Hispanic or Latino adults with a low-grade glioma brain tumor (grades 2 or 3) to join a new health education program. In this program, we will talk about what low-grade glioma and how genes affect it, how to get ready for a doctor visits, how to find help in your community, what are quality of life needs, and how to take part in research.