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Healthy Volunteer
Study Protocol Number Study Title and Description
21-4757
Virtual Physical Activity Program for Older Family Care Partners of People with Heart Failure

This study is testing a virtual exercise program to help older adults who take care of family members. We hope to help them feel better both physically and mentally, so they can feel more confident and capable in their caregiving.

18-2154
Using Ultrasound and MRI to Study Heart Health of Unborn Babies

This study wants to learn about the best way to take pictures of unborn babies' hearts to better identify certain heart health problems.

25-1531
REST: Improving Sleep Health and Timing to Support Health in Teens

The purpose of this study is to learn if improving sleep habits and sleep timing can help improve blood sugar and heart health in teens who do not get enough sleep.

25-0286
Study on Brain and Vascular Health in People with Endometriosis

This study wants to learn more about heart and brain health of people with and without endometriosis.

23-1852
A Study Comparing Care Based on Heart Scan Results to Care Based on Risk Factor

This study will look at two ways to prevent heart and blood vessel problems. It will test which treatment works better for people who may have hidden artery disease because of conditions like diabetes or metabolic syndrome. One way uses your risk factors, and the other way uses pictures of your heart arteries to guide care.

23-0516
Studying Heart Problems During Rest & Exercise in People with Chronic Obstructive Pulmonary Disease

This study wants to learn more about how the right side of the heart works in people with chronic obstructive pulmonary disease (COPD). We want to see how the heart responds to high blood pressure in the lungs, both while resting and during exercise. The goal is to find patterns that could lead to better treatments for people with COPD.

25-0466
Combining Ziftomenib and Imatinib to Treat Advanced Gastrointestinal Stromal Tumors

This study wants to find a dose of ziftomenib that people with advanced gastrointestinal stromal tumors (CIST) can handle safely when taken with imatinib. We also want to learn how well these two drugs work together.

24-0284
Improving Sleep and Heart Health in Veterans with PTSD by Treating Nightmares

This study is testing a digital sleep treatment, called NightWare, to see if it can improve sleep and heart health in veterans by reducing nightmares related to post-traumatic stress disorder (PTSD).

26-0365
Study Evaluating Muvalaplin to Lower Lipoprotein and Reduce Heart Risk in Adults

This study wants to learn more about muvalaplin (LY3473329). Muvalaplin is being studied to treat high lipoprotein, which is a type of unhealthy fat in your blood. The goal of this study is to see if muvalaplin can lower the risk of serious health problems, such as heart attack or stroke, and see what side effects people may have.

25-0503
Dysautonomia in Down Syndrome

This study wants to learn how adults with Down syndrome (DS) respond to everyday stress compared with adults without DS of the same sex and age. This study will look at changes in heart rate, blood pressure, and other body responses during stress.

24-1860
Embolization of Arterial Hemorrhage in the Peripheral Blood Vessels using Onyx LES

This study looks at whether a new product called Onyx LES is safe and works well when doctors use it to stop bleeding in blood vessels outside the brain and heart in adults that have arterial hemorrhage in the peripheral blood vessels.

24-0908
Cardiovascular Health in Lymphoma Survivors After Chemotherapy

We are studying how a type of chemotherapy called doxorubicin affects the heart and arteries. We are looking for lymphoma survivors and healthy adults to join this study.

23-1518
The Impact of Low Estrogen on the Heart and Body Composition in Women

We want to learn how estrogen levels during menopause might affect artery health, body fat, and risk of heart disease in women with regular periods.

20-2723
Relationship between Cardiac Health and Exercise Capacity in Men and Women with and without Type 2 Diabetes

We are recruiting individuals with type 2 diabetes (T2D) in need of an exercise program, aged 30 to 55, to help us test how exercise affects heart health, blood vessels, and blood sugar.

24-1948
How Do Nightmares from Trauma Affect Heart and Artery Health in Women

We want to learn how nightmares from trauma or posttraumatic stress disorder (PTSD) affect heart and artery health in women. We also want to see if a treatment called NightWare, which is used on a smartwatch, can help women with these nightmares sleep better and improve their heart and artery health.

24-1316
Research Study on Exercise and Heart Health in Men and Women

This study wants to learn how age and sex affect how our blood vessels age and how exercise (both short-term and long-term) changes the body.

25-2690
A Study of Montelukast for Kidney and Heart Health in Young Adults with Type 2 Diabetes

The goal of this study is to learn more about inflammation and how well the kidneys and blood vessels work in young adults with type 2 diabetes (T2D).

23-1360
Testing the Effects of Dapagliflozin in People with a Kidney Transplant

This study wants to learn how well and safe dapagliflozin works in people who had a kidney transplant and have Type 2 or post-transplant diabetes. We will look at how dapagliflozin affects the function of your kidney, heart, and blood vessels. We are studying the effects/impact of dapagliflozin (a SGLT2 inhibitor) on: - Kidney function - Protein in the urine - Blood vessel function - Heart f...

26-0203
Smart Basal Insulin Dosing Study for Adults with Type 2 Diabetes

This study wants to find out if a mobile app that suggests daily insulin doses is safe and works well for adults with type 2 diabetes.

25-0943
Enhancing Health in Women During the Menopause Transition

This study wants to learn how late menopause affects women. This study wants to see whether diet education, lifestyle changes, and medication can help women feel healthier. We are looking for women ages 45 to 55 who are in late menopause to join.

20-2465
Optimizing pulsatility during cardiopulmonary bypass to reduce acute kidney injury: Prospective Observational Study

Preserving endothelial function with pulsatility during CPB will be associated with less AKI after cardiac surgery.

19-3027
Learning More About Turner Syndrome (INSIGHTS Registry)

This study wants to collect medical information from people with Turner Syndrome at clinics across the country to learn more about the condition. We are gathering this data in a national registry to help improve the health and care for people with Turner Syndrome in the future.

25-2220
Comparing Growth Hormone Treatments for Children with Short Stature

In this study, we are comparing two growth hormone treatments, lonapegsomatropin and somatropin, for children with short stature due to Turner syndrome, SHOX deficiency, being born small for gestational age, or idiopathic short stature. We want to learn how safe these treatments are and how well they help children grow.