We want to find out how well the medicine Belimumab works in real life for adults who have active lupus nephritis. This study also wants to see if belimumab helps keep the kidneys healthy for a long time.
We want to learn if ravulizumab can help slow down or stop kidney problems and lower protein in the urine. We will also compare ravulizumab to a placebo (a substance with no medicine) to see how well it works.
This study is testing a new drug called SC291 to see if it is safe and if it can help treat serious autoimmune diseases that have come back or stopped responding to treatment.
In this study, we want to see if two anti-rejection drugs (belatacept and sirolimus) can better protect your new kidney after kidney transplant, compared to the currently used drugs (tacrolimus and MMF).
This study wants to learn more about how the right side of the heart works in people with chronic obstructive pulmonary disease (COPD). We want to see how the heart responds to high blood pressure in the lungs, both while resting and during exercise. The g
To test a new medication (BION-1301) for the treatment of IgAN.
This study will test if a supplement called equol can help improve blood flow in women after menopause, both with and without kidney disease. Researchers will check how equol affects blood vessels one, two, and three hours after it’s taken.
In this study we want to gather more information about the safety and tolerability of a drug called ferric citrate for treating children with chronic kidney disease who have hyperphosphatemia.
To evaluate the efficacy of VIB4920 antoagonism of CD40L in achieving a complete renal response in active lupus nephritis
This study plans to learn more about the effects of having too much acid in the blood as a result of having a kidney transplant. This study will look at how acid levels in the blood affect the function of blood vessels and the transplanted kidney.
In this study, we want to learn more about how doctors use a special type of dialysis machine called CARPEDIEM to treat babies that have kidney problems. We want to collect medical information from babies who were treated with this machine to help improve
To establish whether or not nicotinamide riboside will improve large artery stiffness in patients with stage III and IV chronic kidney disease.
To determine if the chronic administration of riociguat improves exercise hemodynamic profiles measured by tight heart catheterization (RHC) - in patients with subjective exercise limitation at least 6 months post-PTE surgery.
Develop a database of subjects with inflammatory renal disease. Develop a data and biobank containing securely stored data, blood, urine, stool, endothelial cell samples, and kidney biopsy tissue.
To see if DMX-200 reduces proteinuria and slows the loss of kidney function when taken at the same time as an ARB in patients with focal segmental glomerulosclerosis (FSGS)
To demonstrate the superiority of iptacopan compared to placebo in reducing proteinuria at 6 months of treatment
To learn more about the diseases that cause nephrotic syndrome so that improved treatments can be developed.