Impact of Fever Prevention in Brain Injured Patients (INTREPID)
University of Colorado Hospital Patients randomized to the fever prevention group will have ArcticGel Pads placed on their body. These will be connected to the Arctic Sun System. The system will be programmed to keep the patient's body temperature at 98.6. Treatment will last for 14 days or until ready to be discharge... |
Intermuscular adipose tissue (IMAT) - protagonist in sarcopenia and insulin resistance in humans
Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital Participants will be asked to complete a screening visit prior to their procedure which will include a fasted OGTT, DEXA scan, muscle strength testing, and MRI of the abdomen and thigh. During surgery, the research team will perform a muscle biopsy of the vastus lateralis, and the surgeon ... |
The use of thoracic epidural, paravertebral nerve blockade and video-assisted intercostal nerve cryoablation for postoperative analgesia after minimally invasive repair of pectus excavatum
Childrens Hospital Colorado The study is to learn more about treating pain after having a minimally invasive repair of pectus excavatum while randomly assigning different pain methods that are typically used for this procedure.... |
Optimizing pulsatility during cardiopulmonary bypass to reduce acute kidney injury: Prospective Observational Study
University of Colorado Hospital Blood, urine, and bone marrow will be collected to analyze biomarkers of acute kidney injury risk. Sublingual microscopy will be used to collect images in the mouth. This is to study the following aims: Aim 1: Determine the effect of pulsatility during CPB on endothelial function. We wil... |
Pre-IVF treatment with a GnRH antagonist in women with endometriosis - A prospective double-blind placebo-controlled trial JHM IRB
Outpatient CTRC, Outpatient CTRC, SGF Colorado - Colorado Springs, SGF Colorado - Denver This study is looking for women with endometriosis that are about to start in-vitro fertilization procedures to see how Orilissa, a drug to help with symptoms of endometriosis, affects fertility treatment. Participants can expect up to 5 study visits spanning over approximately 6 months, t... |
Phase I clinical trial utilizing direct peritoneal resuscitation in liver transplant recipient population at increased risk of return to the operating room and early allograft dysfunction.
University of Colorado Hospital This study is being conducted to assess the safety of Direct Peritoneal Resuscitation (DPR) in high-risk liver transplant patients. The investigators want to also identify if this method of recovery after large surgery has the same benefits in liver transplant patients as have been appreci... |
DEFIANCE: ClotTriever vs. Anticoagulation for DVT
Department Specific Free Standing Clinic, Highlands Ranch Hospital, University of Colorado Hospital This study is a prospective, multicenter, randomized controlled trial of an interventional strategy using the ClotTriever System to achieve and maintain vessel patency (ClotTriever Intervention Arm) versus conservative medical management using anticoagulation therapy alone (Conservativ... |
Improving patient-centered Ob-Gyn care for Black women: Co-designing solutions to mitigate systemic racism, discrimination and bias
Department Specific Free Standing Clinic, University of Colorado Hospital CU OB-Gyn providers are committed to addressing racial inequities in healthcare. We invite patients, advocates and members of the community who identify as Black, African American, African, Afro-Latinx or Afro-Caribbean to share your experiences and feedback, especially those that have rec... |
Postoperative Utilization of Incentive Spirometry with and without Electronic Patient Reminders
University of Colorado Hospital All eligible patients arriving to the PACU every day will be provided with a Vyaire Medical's AirLife volumetric incentive spirometer and instructions to perform 3 IS breaths every 20 minutes until discharge from PACU. The IS device will be set up with the breath volume considered adequate... |
A Phase 3B, Single-Arm, Open-Label Study to Evaluate Bone Mineral Density with Long-Term Use of Relugolix Combination Tablet in Premenopausal Women with Heavy Menstrual Bleeding Associated with Uterine Fibroids or Moderate to Severe Pain Associated with Endometriosis
Outpatient CTRC, University of Colorado Hospital Currently, this medicine is approved by the United States (US) Food and Drug Administration (FDA) for up to 2 years of use for the management of premenopausal women with moderate to severe pain associated with endometriosis. The sponsor is investigating if this medication can be taken for ... |
CLEAN-PE: A Prospective, Multicenter Study to Evaluate the Safety and Efficacy of an Aspiration Thrombectomy System in Acute Pulmonary Embolism
Outpatient CTRC, University of Colorado Hospital Prospective, single-arm, multicenter study. Approximately 125 subjects will be screened for 105 enrolled at up to 15 investigational sites in the United States.... |
Perioperative Informatics of Colorado (PICO) Database
University of Colorado Hospital The development of this database will allow us to study various aspects of care provided by members of the Department of Anesthesiology at the University of Colorado School of Medicine (CU-DOA) and their association with perioperative outcomes or hospital resource utilization. The informat... |