Your search for "Infectious Diseases" found 26 matches:
NIH RECOVER: A Multi-site Observational Study of Post-Acute Sequelae of SARS-CoV-2 Infection in Adults (Pregnancy Arm)

This study is looking at the long-term implications of COVID-19 infection in pregnant patients. Study participants may be asked to answer sets of questions about ongoing symptoms, give samples such as blood and urine and possibly have some other imaging tests. ...

Protocol #: 22-2323

Safety, Tolerability, and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants with both Chronic Hepatitis B and HIV

Protocol #: 22-2156

Location: CTRC Inpatient, Outpatient CTRC, University of Colorado Hospital

Evaluation of the feasibility, acceptability, and effectiveness of TelePrEP for at-risk youth in Colorado

This study aims to assess whether PrEP delivery via a telehealth (termed TelePrEP throughout) approach supports persistence and retention on oral PrEP for young people and identify barriers and facilitators of TelePrEP for youth. The proposed research will address the critical need to iden...

Protocol #: 22-0588

Location: Childrens Hospital Colorado

A Phase 3, multicenter, randomized, double-blind, 48-week study of the clinical and antiviral effect of S-217622 compared with placebo in non-hospitalized high-risk participants with COVID-19

Protocol #: 22-0587

Location: Outpatient CTRC

A5359: A Phase III Study to Evaluate Long-Acting Antiretroviral Therapy in Non-adherent HIV-Infected Individuals. Version 1.0 07/05/2018

Protocol #: 18-1493

Location: University of Colorado Hospital

A5357: A Study of Long-Acting Cabotegravir Plus VRC01LS to Maintain Viral Suppression in Adults Living with HIV-1

Protocol #: 18-2315

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

The High-Intensity Exercise to Attenuate Limitations and Train Habits (HEALTH) in Older Adults with HIV

Protocol #: 19-1985

Location: Brain Imaging Center - BIC, Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

A5380: A Phase II Trial of Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection (PURGE-C)

Protocol #: 20-0303

Location: Outpatient CTRC, University of Colorado Hospital


Protocol #: 20-0889

Location: Childrens Hospital Colorado

Influenza-Specific Immunity and Responses to Inactivated Influenza Vaccine in Infants: Effect of Maternal Vaccination During Pregnancy

This study aims to learn more about how babies' immune systems react to the influenza vaccine and if there is any difference between babies whose mothers receive the influenza vaccine, or not, before the baby is born. Study visits will take place during prenatal care and delivery as well a...

Protocol #: 20-1074

Location: Childrens Hospital Colorado, University of Colorado Hospital

Effect Of Neonatal BCG Administration On Innate And Adaptive Immune Responses To Infection With Rotavirus Live Attenuated Vaccine Strain In HIV-Exposed And Unexposed Infants

Women in this study will consent in the third trimester and have cord blood collected at the time of delivery. The infant will have four visits at Children's Hospital Colorado....

Protocol #: 20-0593

Location: Childrens Hospital Colorado, Highlands Ranch Hospital, University of Colorado Hospital

A5418 A Randomized, Placebo-Controlled, Double-Blinded Trial of the Safety and Efficacy of Tecovirimat for the Treatment of Human Monkeypox Virus Disease Study of Tecovirimat for Human Monkeypox Virus (STOMP)

Phase 3, randomized, placebo-controlled, double-blind trial of tecovirimat for the treatment of human monkeypox virus (HMPXV) disease. The study will also include a cohort of people who will receive open-label tecovirimat including people with protocol-defined severe HMPXV, pregnant and br...

Protocol #: 22-1761

Location: Childrens Hospital Colorado

Engaging practices and communities in the development of interventions to promote HPV vaccine uptake

Protocol #: 18-0338

Location: Department Specific Free Standing Clinic

A Phase 3, Double-Blind, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Subcutaneous Twice Yearly Long-Acting Lenacapavir for HIV Pre Exposure Prophylaxis in Cisgender Men, Transgender Women, Transgender Men, and Gender Non-binary People ≥ 16 Years of Age who Have Sex with Male Partners and are at Risk for HIV Infection (GS-US-528-9023)

Protocol #: 21-3252

Location: Outpatient CTRC, Outpatient CTRC

Doravirine for Persons with Excessive Weight Gain on Integrase Inhibitors and Tenofovir Alafenamide (The Do IT Study)

Protocol #: 21-3534

Location: Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital

A Phase 2b/3 Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-1654 in Healthy Pre-Term and Full-Term Infants

The ASSERVO study is testing a potential medicine for infants to see if it may help prevent lower respiratory infections caused by RSV. Study participation includes 1 dose of the medicine or placebo, approximately 3 blood draws, e-diary entries, and nasal swabs collected during any respir...

Protocol #: 21-3387

Location: Childrens Hospital Colorado

Randomized, Controlled Trial to Evaluate the Anti-inflammatory Efficacy of Letermovir (Prevymis) in Adults with Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive ART and Its Effect on Chronic Inflammation, HIV Persistence, and Other Clinical Outcomes (ELICIT)

Protocol #: 21-4059

Location: Outpatient CTRC, Outpatient CTRC

A Phase 3, Multicenter, Randomized, Partially Blinded, Palivizumab-Controlled Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of MK-1654 in Infants and Children at Increased Risk for Severe RSV Disease

This trial is testing a study medicine to learn if it can help prevent RSV infection in babies who are more likely to get severe RSV illness. Infants will be randomized to receive either Synagis or the study drug. There are approximately 3 blood draws per season, and participants will be ...

Protocol #: 21-4176

Location: Childrens Hospital Colorado

Respiratory Virus Transmission Network (RVTN)

The study will collect information from you and other household members on symptoms and patterns of contacts to learn how the virus is transmitted. Your household will be compensated for participating in this study....

Protocol #: 21-4270

Location: Childrens Hospital Colorado

Phase II, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-based anti-Cytomegalovirus (CMV) Vaccine (Triplex?), in Adults with Both Human Immunodeficiency Virus (HIV)-1 and CMV Who Are on Potent Combination ART with Conserved Immune Function

Protocol #: 21-4360

Location: Outpatient CTRC, Outpatient CTRC

PHACS Health Outcomes around Pregnancy and Exposure to HIV/ARVs (HOPE)

The study is designed to evaluate the health outcomes of women living with HIV over time. Women who elect to participate in this study complete a combination of online surveys, clinical assessments, and interviews, with a blood draw and other samples collected at the time a person enrolls ...

Protocol #: 21-3844

Location: Childrens Hospital Colorado, University of Colorado Hospital

A Multi-site Observational Study: NIH RECOVER Study of Long COVID in Adults

This is a longitudinal study enrolling individuals with and without SARS-CoV-2 infection at varying stages before and after infection and with or without post-acute sequelae of SARS-CoV-2 (PASC). The aim is to better understand risk factors and occurrence of PASC. Study data including ...

Protocol #: 21-4528

Location: Cherry Creek Medical Center, Highlands Ranch Hospital, Outpatient CTRC, University of Colorado Hospital

Gut microbiome effects on intestinal barrier function in metabolic syndrome in HIV positive men who have sex with men

Protocol #: 22-1180

Location: Outpatient CTRC, University of Colorado Hospital

A Randomized, Placebo-Controlled, Double-Blinded Trial of the Safety and Efficacy of Tecovirimat for the Treatment of Human Monkeypox Virus Disease

Eligible and consented participants for the randomized arms (N=530) will be randomized 2:1 to receive either tecovirimat or placebo; participants with severe disease, significant skin conditions, participants with severe immune suppression will receive open-label tecovirimat. Participants ...

Protocol #: 22-0797

Location: Adult Infectious Disease Clinical Trials Center, Outpatient CTRC, University of Colorado Hospital

Characterization of Mpox Antibody Response after JYNNEOS Vaccination Among Persons with HIV

Protocol #: 23-0776

Location: Outpatient CTRC, University of Colorado Hospital

A Multicenter, Adaptive, Randomized, Controlled Trial Platform To Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections - Appendix E-2: Immune Modulation Strategy Trial

Protocol #: 23-0870

Location: University of Colorado Hospital