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SPOT Study: The Impact of Auditory Access on the Development of Speech Perception
Childrens Hospital Colorado, CU Anschutz non-hospital research facilities The goal of our research is to improve services for children who are at risk for language learning (i.e., hearing loss, reading difficulties). We do this by measuring how infants tell the difference between speech sounds. A child’s ability to differentiate between speech sounds predicts th... |
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Effects of exercise and social gaming on the brain in autism spectrum disorders
CU Anschutz non-hospital research facilities Participants in the study will be asked to participate in a 10-week intervention of exercise or social gaming to help us learn more about how exercise and social gaming affect brain responses.... |
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Mindfulness-Based Intervention for Adolescents with Chronic Migraine
Childrens Hospital Colorado If eligible, your teen would participate in a 6-week virtual group program with other teens with migraine. Your teen would also complete questionnaires before and after the group program. Possible benefits of the study include learning mindfulness-based skills, feeling less stressed, p... |
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GBM AGILE Global Adaptive Trial Master Protocol: An International, Seamless Phase II/III Response Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens In Newly Diagnosed and Recurrent GBM (GCAR-7213)
Cherry Creek Medical Center, CTRC Inpatient, Highlands Ranch Hospital, Longs Peak Hospital, University of Colorado Hospital Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple therapies in newly diagnosed (ND) and recurrent GBM. Its goals are to identify effective ... |
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Endovascular treatment of acutely ruptured shallow intradural aneurysms not amendable to clipping and coiling with the pipeline vantage embolization device
University of Colorado Hospital The purpose of this study is to assess the safety (short and long term side effects) and effectiveness (how well it stops the blood flow into the aneurysm) of the study device for the treatment of adults (22 – 80 years of age) with acutely ruptured, intradural (inside the head) aneurysms t... |
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The Effects of Aerobic Exercise on Parkinson's Disease
Outpatient CTRC, University of Colorado Hospital This is an exercise research study for people who have been recently diagnosed with Parkinson's disease. Aerobic exercise is a vital treatment for people living with Parkinson's disease. Although anti-parkinsonian medication helps alleviate Parkinson's symptoms, it is not known to slow ... |
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ALZHEIMER'S CLINICAL TRIAL CONSORTIUM FOR DOWN SYNDROME (ACTC-DS)
TRIAL-READY COHORT - DOWN SYNDROME (TRC-DS)
Outpatient CTRC, Outpatient CTRC, University of Colorado Hospital TRC-DS is part of a larger movement working with people with Down syndrome to advance Alzheimer's disease therapies and potential cures for this population. The Alzheimer's Clinical Trials Consortium-Down Syndrome (ACTC-DS) is a large collaboration of researchers conducting clinical trials... |
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Teen Brain Imaging Study on Irritability and Social Information Processing
Brain Imaging Center (BIC), Brain Imaging Center (BIC) - Scan Read Interested in how irritability affects how teens interpret social situations? Our goal is to learn more about how teens think and feel about unclear social situations and how irritable mood may relate to negative thoughts and feelings about these social situations.... |
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NRG-BN011, A Phase III Trial of Lomustine-Temozolomide Combination Therapy Versus Standard Temozolomide in Patients With Methylated MGMT Promoter Glioblastoma (NCT 05095376)
Greeley Campus, Harmony Campus, Medical Center of the Rockies, Memorial Hospital Central, Memorial Hospital North, Poudre Valley Hospital |
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A 2-part Phase 2 Study of Safety, Pharmacokinetics and Biomarkers
in Children with Duchenne Muscular Dystrophy including a Randomized, Double-Blind, Placebo-Controlled Part A, Followed by an Open-Label Part B
Childrens Hospital Colorado This is a 2-part multi-center, Phase 2 study to evaluate the effect of EDG-5506 on safety, PK and biomarkers of muscle damage in approximately 27 children with DMD treated with oral, once daily EDG-5506 for 12 months. Part A will include a 12-week, randomized, double-blind, placebo-contr... |
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Validation of Instruments Measuring Caregiver Experiences (Caregiver VOICE Study)
Lone Tree Medical Center, University of Colorado Hospital Attention, Dementia Caregiving Dementia caregivers have important roles in supporting someone with Dementia. We are interested in hearing the voices of those caregivers. Participation in this telephone based study will take approx. 30-45 minutes. We are interested in your perspective o... |
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A Phase 1/2, First in Human, Multiple-dose, 2-part Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NS-050/NCNP-03 in Boys with Duchenne Muscular Dystrophy (DMD)
Childrens Hospital Colorado This is a Phase 1/2, first in human, multicenter, two-part study of MAD levels for 12 weeks of treatment followed by 24 weeks of open-label treatment with a selected dose of NS-050/NCNP-03 administered once weekly to ambulant boys with DMD, who have a DMD mutation amenable to exon 50 sk... |
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A PHASE IV OPEN-LABEL STUDY EVALUATING THE EFFECTIVENESS AND SAFETY OF
RISDIPLAM ADMINISTERED IN PEDIATRIC PATIENTS WITH SPINAL MUSCULAR ATROPHY
WHO EXPERIENCED A PLATEAU OR DECLINE IN FUNCTION AFTER GENE THERAPY
Childrens Hospital Colorado This is a Phase IV, open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam (Evrysdi®) administered in pediatric patients with SMA who previously received onasemnogene abeparvovec and experience a plateau or decline in function. Patients t... |
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A PHASE IV OPEN-LABEL STUDY EVALUATING THE EFFECTIVENESS AND SAFETY OF RISDIPLAM ADMINISTERED AS AN EARLY INTERVENTION IN PEDIATRIC PATIENTS WITH SPINAL MUSCULAR ATROPHY AFTER GENE THERAPY
Childrens Hospital Colorado This is a Phase IV, open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam (Evrysdi®) administered as an early intervention in pediatric patients with SMA who previously received onasemnogene abeparvovec. Patients to be enrolled are chil... |