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To prospectively collect data regarding the diagnosis and treatment of orthopedic infections including upper and lower limb as well as pelvic and spinal infection in order to improve quality of care. The database will be used for subsequent future research.

To collect data on the recurrence rate and outcomes of benign and primary/metastatic malignant tumors seen in Orthopaedic patients at the University of Colorado Hospital.

To collect prospectively (after informed consent) fresh, excess surgical tissues, blood and other bodily fluids, and saliva from patients with HNC slated to undergo biopsy or surgical resection, and to collect prospectively optional samples from patients with HNC slated to undergo other therapies