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Study Protocol Number Study Title and Description
25-2548
A Research Study Comparing Two Treatments for Gastrointestinal Stromal Tumors

The purpose of this study is to find out whether the study drug IDRX-42 can help your gastrointestinal stromal tumor (GIST) compared with another drug called sunitinib.

Cancer
Adult
25-0466
Combining Ziftomenib and Imatinib to Treat Advanced Gastrointestinal Stromal Tumors

This study wants to find a dose of ziftomenib that people with advanced gastrointestinal stromal tumors (CIST) can handle safely when taken with imatinib. We also want to learn how well these two drugs work together.

Cancer
Cancer Stage and Treatment Status
Adult
Compensation
24-2282
A Master Protocol for the Multi-cohort, Open-label, Phase 1/2 Study of DCC-3009 in Participants With Gastrointestinal Stromal Tumors (GIST)

• To evaluate the safety and tolerability of DCC-3009 as monotherapy in participants with advanced GIST. • To determine the recommended dose(s) for expansion in Module A, and if reached, the maximum tolerated dose (MTD) of DCC-3009 as monotherapy.

Cancer
Adult