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Healthy Volunteer
Study Protocol Number Study Title and Description
26-1228
MENO-RISE: Pilot Trial of a Stress Resilience Intervention for Perimenopausal Depression and Cognitive Concerns in Women with Histories of Childhood Adversity

This research study plans to examine an online stress-resilience (mindfulness-based) program for women in perimenopause who have experienced stress earlier in life. It is also designed to learn about the feasibility, acceptability, and effects of the program on stress, mood, thinking abilities, and health markers.

26-0124
Nature-based and Doula Support to Help Improve Sleep and Stress for New Mothers

We are looking for women who are within six weeks of giving birth to help us learn how doula support and spending time in nature can lower stress, improve sleep, and support overall wellbeing. This study looks at ways to help mothers recover and thrive during the early weeks after giving birth.

25-1257
Learning How Infections During Pregnancy Affect Babies

In this study we want to learn how babies are affected when their mothers have a viral infection during pregnancy. To do this, we will collect blood samples from pregnant women who have viral infections (like COVID-19) and those who do not.

25-0286
Study on Brain and Vascular Health in People with Endometriosis

This study wants to learn more about heart and brain health of people with and without endometriosis.

24-1948
How Do Nightmares from Trauma Affect Heart and Artery Health in Women

We want to learn how nightmares from trauma or posttraumatic stress disorder (PTSD) affect heart and artery health in women. We also want to see if a treatment called NightWare, which is used on a smartwatch, can help women with these nightmares sleep better and improve their heart and artery health.

23-1702
Low-Fat Meal plan

This study wants to learn more about how the food we eat affects the reproductive hormones of adult women with obesity.

24-0401
S2206: Phase III Trial of Neoadjuvant Durvalumab (NSC 778709) plus Chemotherapy versus Chemotherapy Alone for Adults with MammaPrint Ultrahigh (MP2) Hormone Receptor (HR) Positive / Human Epidermal Growth Factor Receptor (HER2) Negative Stage II-III Breast Cancer,

This phase III trial compares the addition of an immunotherapy drug (durvalumab) to usual chemotherapy versus usual chemotherapy alone in treating patients with MammaPrint Ultrahigh (MP2) stage II-III hormone receptor positive, HER2 negative breast cancer. Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the a...

23-2461
Protocol NRG-BR009, A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression plus Endocrine Therapy in Premenopausal Patients with pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score less than or equal to 25 (OFSET)

This Phase III Trial will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among premenopausal, early- stage breast cancer (EBC) patients with estrogen receptor (ER)-positive, HER2-negative tumors and 21-gene recurrence score (RS) between 16-25 (...

23-1513
How Menstruation Affects Blood Sugar and Exercise in Females with Type 1 Diabetes

This study wants to see how blood sugar changes with sex hormones during regular menstrual cycles or when using hormonal birth control. We also want to learn how exercise and hormonal birth control affect blood sugar.

23-1518
The Impact of Low Estrogen on the Heart and Body Composition in Women

We want to learn how estrogen levels during menopause might affect artery health, body fat, and risk of heart disease in women with regular periods.

22-1840
PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life - The PROMISE Study

This study wants to learn more about how exposures during pregnancy like infections, diet and growth, can affect a baby’s chances of developing type 1 diabetes later in life.

21-3533
Study Exploring Genetic Causes for Recurrent Pregnancy Loss

We are looking for couples that have had two or more pregnancy losses with no known cause. We want to find out if genetics might be a reason for recurrent pregnancy loss (RPL).

19-3027
Learning More About Turner Syndrome (INSIGHTS Registry)

This study wants to collect medical information from people with Turner Syndrome at clinics across the country to learn more about the condition. We are gathering this data in a national registry to help improve the health and care for people with Turner Syndrome in the future.

19-2327
MammaPrint, BluePrint, and Full-genome Data Linked with Clinical Data to Evaluate New Gene EXpression Profiles: An Adaptable Registry (FLEX Registry)

The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive de...

24-1357
How Our Genetics Affect Birth Control

This study wants to find out how differences in our DNA might affect how birth control works in our bodies and which side effects they may experience.

25-2688
Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health

This research study wants to learn more about how estradiol patch treatment affects brain function, health and wellbeing in healthy women who have experienced menopause.

23-2499
Preventing Mood, Anxiety, and Trauma Symptoms After Cesarean Delivery

This study will look at whether a one-time session can help you prepare for delivery, reduce concerns about giving birth, and improve perinatal mood, anxiety, and trauma symptoms (PMATS).

26-0782
Exploring Shoulder Placement for the Nexplanon Birth Control Implant

This study wants to find out how the body responds when the birth control implant, Nexplanon, is placed over the shoulder bone instead of in the arm.

25-0095
Equol for Better Blood Vessel Health in Postmenopausal Women with Kidney Disease

This study wants to learn how equol, a supplement made from soy, affects blood vessel health in postmenopausal women with chronic kidney disease (CKD). This study wants to see if taking equol for 12 weeks can help blood vessels work better.

25-0943
Enhancing Health in Women During the Menopause Transition

This study wants to learn how late menopause affects women. This study wants to see whether diet education, lifestyle changes, and medication can help women feel healthier. We are looking for women ages 45 to 55 who are in late menopause to join.

24-1269
The Impact of Estrogen on Women's Reproductive Hormones and System

This study wants to learn more about how estrogen affects women's reproductive hormones and system.

21-4941
Semaglutide as a Treatment for Adolescents and Adults with Polycystic Ovary Syndrome (PCOS)

In this study we want to learn if a medicine approved for diabetes and weight loss called Ozempic® and Wegovy® (semaglutide) can help improve the frequency of periods and the way the body uses sugar in women with polycystic ovary syndrome (PCOS).