| Study Protocol Number | Study Title and Description |
|---|---|
| 26-0236 |
Learning About Physical Activity in Teens with Type 2 Diabetes
In this study, we want to learn more about what helps and what makes it harder for teens with type 2 diabetes to be physically active. To do this, we are talking to teens and their parents/caregivers in small group discussions. |
| 23-1727 |
How Well Does Sogroya Work for Adults with Growth Hormone Deficiency
We want to learn more about how safe Sogroya (somapacitan) is and how well it works for people with growth hormone deficiency. To join, you must already be taking or be planning to take Sogroya. |
| 26-0145 |
A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Baricitinib to Preserve Beta
Cell Function in Participants Newly Diagnosed with Type 1 Diabetes Aged ≥1 to <36 Years
(BARICADE-PRESERVE)
To demonstrate the superiority of baricitinib versus placebo in the preservation of beta-cell function, as measured by C-peptide, in younger adult and pediatric participants with new-onset T1D after 52 weeks of treatment |
| 25-2220 |
Comparing Growth Hormone Treatments for Children with Short Stature
In this study, we are comparing two growth hormone treatments, lonapegsomatropin and somatropin, for children with short stature due to Turner syndrome, SHOX deficiency, being born small for gestational age, or idiopathic short stature. We want to learn how safe these treatments are and how well they help children grow. |
| 25-2690 |
A Study of Montelukast for Kidney and Heart Health in Young Adults with Type 2 Diabetes
The goal of this study is to learn more about inflammation and how well the kidneys and blood vessels work in young adults with type 2 diabetes (T2D). |
| 25-1730 |
Studying the Effects of OPT101 in People with Type 1 Diabetes
This research study is testing whether the investigational drug OPT101 is safe and helpful for people with Type 1 Diabetes (T1D). |
| 26-0239 |
Using GLP-1 Drugs to Treat Metabolic Dysfunction Associated Steatotic Liver Disease
The main goal of this study is to see how well two drugs, tirzepatide and retatrutide, work for treating metabolic dysfunction associated steatotic liver disease compared to placebo. |
| 25-0693 |
New Drug Treatment to Protect Insulin-Making Cells in Kids and Adolescents with Type 1 Diabetes
In this study we are testing a new drug called teplizumab to see if it can help protect the cells that make insulin in people with type 1 diabetes. We want to know if it can improve blood sugar levels, reduce the need for extra insulin, and lower the risk of low blood sugar. |
| 25-0689 |
A Phase 1b/2a Double Blind, Placebo Controlled Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of CNP-103 in Participants Ages 12-35 with Recent Onset Stage 3 Type 1 Diabetes
To assess the pharmacodynamic and clinical efficacy of CNP-103 |
| 23-1702 |
Low-Fat Meal plan
This study wants to learn more about how the food we eat affects the reproductive hormones of adult women with obesity. |
| 24-0240 |
Studying Sotagliflozin to Help Slow Kidney Damage in People with Type 1 Diabetes: SugarNSalt Trial
This study wants to learn more about whether a drug called sotagliflozin (SOTA) can slow down the loss of kidney function in people with type 1 diabetes and diabetic kidney disease. |
| 24-0361 |
DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
We are studying adolescents who may be at higher risk of getting type 2 diabetes, as they go through puberty. Our goal is to identify early signs that might help predict who will develop the disease. |
| 23-1513 |
How Menstruation Affects Blood Sugar and Exercise in Females with Type 1 Diabetes
This study wants to see how blood sugar changes with sex hormones during regular menstrual cycles or when using hormonal birth control. We also want to learn how exercise and hormonal birth control affect blood sugar. |
| 23-1891 |
The Balanced and Empowered EaTing (BEET) in Diabetes Feasibility Trial
The goals of this study are to refine the implementation and pilot test the feasibility of an adapted cognitive behavioral therapy (CBT), the Balanced and Empowered EaTing in Diabetes (or the BEET Diabetes Program), compared with the original CBT program, delivered by behavioral health providers to treat disordered eating behaviors (DEBs) in patients with type 2 diabetes in real-world clinical set... |
| 23-1852 |
A Study Comparing Care Based on Heart Scan Results to Care Based on Risk Factor
This study will look at two ways to prevent heart and blood vessel problems. It will test which treatment works better for people who may have hidden artery disease because of conditions like diabetes or metabolic syndrome. One way uses your risk factors, and the other way uses pictures of your heart arteries to guide care. |
| 22-1840 |
PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life - The PROMISE Study
This study wants to learn more about how exposures during pregnancy like infections, diet and growth, can affect a baby’s chances of developing type 1 diabetes later in life. |
| 23-2361 |
The COVID-19 and Diabetes Assessment (CODA) Study
This study wants to learn more about how COVID-19 and diabetes are connected. |
| 19-2285 |
Study to Better Understand Rare or Atypical Forms of Diabetes
If your doctor has told you that you have diabetes, but it doesn’t seem like type 1 or type 2, you might be able to join our study. The goal of this study is to better understand different kinds of diabetes that are not common. |
| 25-2469 |
Learning How GLP-1 Medicines Affect Liver Health in People with Type 1 Diabetes
This study looks at how GLP-1 RA medicines like Ozempic and Mounjaro affect the liver in people with type 1 diabetes (T1D) compared to people without T1D. We are focusing on a liver condition called metabolic dysfunction-associated steatotic liver disease (MASLD), which happens when too much fat builds up in the liver and can lead to other health problems. The goal is to find out if these drugs ca... |
| 25-1919 |
Study of Targeted Drug Treatment for Kids and Young Adults with Newly Diagnosed Type 1 Diabetes
In this study we are testing how two drugs, Thymoglobulin ® and verapamil, work together to treat children and young adults with newly diagnosed type 1 diabetes. |
| 24-0061 |
New Device to Manage Insulin Delivery for Kids and Adults with Cystic Fibrosis Related Diabetes
In this study we want to learn how a device that automates insulin delivery (called the iLet Bionic Pancreas) helps people with Cystic Fibrosis Related Diabetes manage their insulin levels. We want to learn how well this device works compared to a normal insulin delivery method. |
| 23-1600 |
Managing Type 2 Diabetes in Teens with Depression
Researchers are trying to find new ways to help improve the mood of teenagers who have Type 2 diabetes (T2D). |
| 25-0943 |
Enhancing Health in Women During the Menopause Transition
This study wants to learn how late menopause affects women. This study wants to see whether diet education, lifestyle changes, and medication can help women feel healthier. We are looking for women ages 45 to 55 who are in late menopause to join. |
| 25-1807 |
A Study Testing if SAB-142 Can Slow the Progression of Type 1 Diabetes in People Recently Diagnosed
This study wants to see if a new drug called SAB-142 in addition to regular insulin therapy can help slow down Type 1 Diabetes (T1D) in people who were diagnosed in the last 100 days. |
| 24-2267 |
Understanding Health Problems Connected to Cystic Fibrosis Related Diabetes (SPeCTRuM)
In this study we want to learn more about how common health problems like high blood pressure, vision problems, and kidney disease are in people with cystic fibrosis-related diabetes (CFRD). |
| 24-1490 |
Impact of Sleep Health in Adolescents with Type 1 Diabetes
In this study we want to see if improving the amount and quality of sleep will help improve the overall health of adolescents that have type 1 diabetes (TID). |
| 19-3004 |
The Role of Complex Sphingolipids in Diabetic Neuropathy
This study wants to learn more about what causes diabetic neuropathy. Diabetic neuropathy happens when nerves are damaged. We look for certain molecules in the blood and skin that may harm nerves. We compare these molecules in people with Type 2 Diabetes who have neuropathy, people with Type 2 Diabetes who do not have neuropathy, and people who do not have diabetes. |
| 23-1267 |
Role of Dulaglutide in Improving Insulin Levels in Adults with Cystic Fibrosis Related Diabetes
In this study we want to understand more about the causes of cystic fibrosis related diabetes (CFRD) and find better ways to treat it. |
| 22-0180 |
Cognitive-Behavioral Therapy and Exercise Training in Teenage Girls At-Risk for Type 2 Diabetes
Our team is here to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or combination of therapy and exercise training lowers stress, improves mood, raises physical activity and fitness, and lowers diabetes risk among teen girls at risk for diabetes. |