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Study Protocol Number Study Title and Description
24-1345
Registry Study for Pregnant Women with Multiple Sclerosis

This registry wants to learn whether taking Vumerity (Diroximel Fumarate) during pregnancy impacts the health of pregnant women with MS or their babies. We will compare the health of women who took Vumerity during pregnancy with the health of women who took other MS medicines or no MS medicine during pregnancy.

25-0870
How Childhood Experiences May Affect Multiple Sclerosis

This study wants to learn how difficult childhood experiences during might impact when certain people get multiple sclerosis (MS), how severe the disease is, and how much it impacts brain health. We hope that this study will help us better understand MS and find ways to improve care and support.

20-1204
Using Biomarkers to Learn More About Parkinson's Disease

The purpose of this study is to keep collecting information from people with and without Parkinson's disease (PD). This study will also measure biomarkers that may be linked to how PD develops and changes over time.

25-0838
A Phase 2/3, Double-Blind, Placebo-Controlled Study of BHV-8000 in Participants with Early Parkinson's Disease

To evaluate the efficacy of 2 dose levels of HBV-8000 compared to placebo by delaying the time to the first qualifying worsening event on the Movement Disorder Society-Unified Parkinson's Disease Rating Scale Part II, through week 48 of the double blinded treatment phase of the trial.

25-2134
A randomized, double-blind, placebo-controlled Phase III study to evaluate the efficacy and safety of remibrutinib in patients with secondary progressive multiple sclerosis

This study wants to know how well the study drug, remibrutinib, works and how safe it is compared to placebo in people with secondary progressive multiple sclerosis (SPMS).

24-1074
REal world experieNce with BRIUMVI® (ublituximAB-xiiy) treated patients: a Longitudinal rEgistry study (ENABLE)

This observational study is to learn more about the safety, effectiveness, and treatment experience of patients prescribed BRIUMVI® (ublituximab-xiiy).

22-0657
Investigating Strength Training in Veterans with Multiple Sclerosis and Mobility Limitations

This study wants to learn more about a strength training program in veterans with Multiple Sclerosis (MS) who use a mobility aid.

25-2727
A Phase 2, Randomized, Double-blind, Three-Arm, Placebo-controlled, Multicenter Study Assessing the Efficacy, Safety and Tolerability of orally administered BMS-986368, a FAAH/MAGL Inhibitor, for the treatment of Agitation in Participants with Alzheimer's Disease (BALANCE-AAD-1)

A clinical study for the treatment of agitation in adults with Alzheimer's disease

25-2429
How Physical Activity Affects Bone Health in Teens With and Without Cerebral Palsy

This study wants to find out how physical activity affects bone strength in teens with and without cerebral palsy (CP).

24-2546
Does Vagus Nerve Stimulation Improve Executive Function?

We are looking for healthy people to help us learn how gently stimulating the vagus nerve through the ear affects thinking skills like decision-making and problem-solving.

20-3000
Brain Alcohol Study

We are looking for healthy adults who can safely have an MRI scan. This study looks at how drinking and not drinking alcohol affects how the brain works.

23-0619
CBD for Individuals with Mild Cognitive Impairment and at Risk for Alzheimer's Disease

Our study is seeking individuals aged 55-85, who have been diagnosed with Mild Cognitive Impairment (MCI) and are at risk for Alzheimer's Disease. The goal of the study is to see whether cannabidiol (CBD) can improve MCI symptoms.

25-1184
A Study to Test Treatment for Age-Related Hearing Loss 

This study wants to see if an FDA-approved drug called Clemastine Fumarate and sound therapy can help improve hearing problems in noisy places that some people get as they age called age-related auditory processing disorder.

25-2345
Exercise and Sleep Tracking at Home for People with Parkinson's Disease

This study wants to learn if a short, high-intensity exercise program can be done safely at home and if this exercise may affect sleep in people with Parkinson's Disease.

24-1207
A Study of Inhibitory Interneurons (NRTX-1001) for the Treatment of Drug-resistant Bilateral Temporal Lobe Focal Seizures

The purpose of this research is to test the safety of an investigational NRTX-1001 cell therapy in participants with drug resistant bilateral mesial temporal lobe epilepsy (MTLE). Another purpose is to see if NRTX-1001 can reduce the number of seizures you have.

23-2572
Effect of Clinical Setting on Breathing Test Results for Children with Early Onset Scoliosis

This study wants to learn if breathing tests (called spirometry) performed in an outpatient clinic give results that are as reliable and accurate as spirometry that is done in a specialized lung function lab.

22-0321
A Feasibility Study of the Ability of the Neural Prosthetic System 2 to Provide Direct Closed Loop Cortical Control of Extracorporeal Devices Through the Use of Intracortical Microstimulation in Patients With Quadriplegia

We hope to learn how safe and effective the Neuroport array plus stimulation is in controlling computer generated images and real-world objects, such as a robotic arm, using imagined movements of the arms and hands.

22-1451
Vagus Nerve Stimulation to Promote Improved Hand Movement in Multiple Sclerosis

We want to learn how stimulating the vagus nerve while moving the hand can help improve fine motor control in people with relapsing-remitting multiple sclerosis (MS), who have trouble moving their hands and arms.

19-2727
Study of the Safety and Effectiveness of Sargramostim for Alzheimer’s Disease

The purpose of this study is to learn if a drug called sargramostim is safe and if it can help improve thinking and memory in people with Alzheimer’s disease.

19-0182
Gene Expression of Cerebral Aneurysms

This study plans to learn more about genes that are expressed in blood vessels in the brain and in the blood of patients without brain aneurysms. This will help us understand diseases that affect those blood vessels such as aneurysms.