This study is for adults age 21 or older who have alcohol use disorder (AUD). It tests whether a medicine called Apremilast can help reduce alcohol cravings compared to a placebo, a pill that looks the same but has no medicine.
This study wants to learn how cannabidiol (CBD) affects drinking in people who drink alcohol often. This study will look to see if CBD can help people drink less and if CBD can help reduce problems linked to alcohol use.
This research study plans to learn more about how a form of brain stimulation called low-intensity focused ultrasound (LIFU) affects the brain and behaviors related to Alcohol Use Disorder (AUD). LIFU is a non-invasive (meaning it does not require surgery or electrodes) form of brain stimulation that uses ultrasonic energy (sound waves that you cannot hear) to affect the function of brain tissue. ...
The purpose of this research study is to learn more about how pain is related to alcohol use and mental health.
We are looking for couples who drink and are 18 years or older to join a study looking at alcohol use among romantic couples.
We are looking for couples, 21 or older, to join a study about how alcohol and media affect relationships.
This study looks at how choline supplements and exposure to cannabis-based products affect pregnancy and child health.
Specific Aims. 1. Determine whether hemp-derived CBD alters cannabis cue-related neural response. A subsample of 52 participants will be recruited from the larger Project 1 (“emerging adult”) randomized controlled trial comparing 400mg/day hemp-derived CBD to placebo. We will conduct a functional MRI scan at enrollment and after 8 weeks in the trial. During the scan, we will conduct a cue-reactiv...
The purpose of this research study is to learn more about how cannabidiol (CBD) may affect cannabis use, effects, and craving.
1. Evaluate the effects of consumption of an oral high (20 mg) vs. placebo (0 mg) THC (dronabinol) on brain activation associated with alcohol salience. 2. Test the effects of high THC vs placebo consumption on alcohol self-administration. 3. Test whether neural response under high THC vs placebo predicts differences in alcohol self-administration in the laboratory or alcohol and cannabis co-...
Our study is seeking individuals aged 55-85, who have been diagnosed with Mild Cognitive Impairment (MCI) and are at risk for Alzheimer's Disease. The goal of the study is to see whether cannabidiol (CBD) can improve MCI symptoms.
We are looking for people aged 25 to 55 who smoke and/or vape cannabis, and people aged 25 to 55 who do not smoke cannabis, to see how cannabis use affects lung health over time.
We are looking for people aged 30 to 50 who are daily users of e-cigarettes (e-cigs) as well as healthy controls to see how vaping nicotine affects lung or general health.
This study wants to look at how endocannabinoids are different in children with and without autism. We are only looking for children who do not have autism to join our study.
We want to learn how a new drug called brexpiprazole (BREX) affects alcohol use and brain function in adults who are not currently getting treatment for Alcohol Use Disorder.
This study wants to find out if cannabidiol (CBD) may help adults with alcohol use disorder lower their alcohol use.
Given the negative symptoms associated with cancer, palliative care, a broad term for the prevention and treatment of adverse effects that arise from a disease or its treatment, continues to be a focus of cancer related research. In recent years one of the most popular options for this has become cannabis. There has been in increase of cancer patients using cannabis for relief; specifically, to im...
We are looking for people who have Opioid Use Disorder to see if whether getting methadone treatment or getting buprenorphine treatment in an office helps them stick to their treatment plan.