How Snacking Affects Brain Responses to Foods and Fullness During Dieting
The goal of this study is to learn more about how different types of snacks may affect brain activity, hunger, and eating behaviors during a diet program.
Why this Research Matters
Many people try to lose weight by eating fewer calories. However, dieting can increase hunger and make it harder to control eating. Researchers want to understand how different types of snacks may affect hunger and brain responses to food during dieting. This study will look at whether eating a daily snack during a diet program can change how the brain responds to food and feelings of fullness.
What to Expect
If you join this study, you will take part in a 12-week diet program. You will be randomly assigned to 1 of 2 snack groups, like flipping a coin. One group will eat pretzels each afternoon and the other group will eat walnuts. You will not be able to choose which snack you receive. During the study, you will complete questionnaires about your eating habits, mood, and daily activities. You will also complete 2 main study visits with a brain scan called magnetic resonance imaging (MRI). You will have 1 MRI before the diet program, and 1 after it ends. During the 12-week program, you will meet with study staff regularly to look over your food logs and receive your snacks.
Study Duration
Your participation will last about 14 to 16 weeks. During this time, you will complete about 9 to 11 study visits, which may include both in-person and online visits. Each main study visit may last about 2-4 hours.
Who can Participate
You may be able to join this study if you:
• Are 25 to 45 years old
• Have a body mass index (BMI) of at least 27
• Are interested in losing weight
You may not be able to join if you:
• Have a nut or wheat allergy
• Have metal or electronic devices in your body that prevent MRI scans
• Feel uncomfortable in small or enclosed spaces (claustrophobia)
Study ID
Protocol Number: 25-1900
Compensation Information
Meet the Team
Principal Investigator