This is a first-in-human study to learn more about the study drug ATG-031 in patients with advanced solid tumors or B-cell Non-Hodgkin Lymphomas.
We are studying how a type of chemotherapy called doxorubicin affects the heart and arteries. We are looking for lymphoma survivors and healthy adults to join this study.
To determine the safety of targeted immunotherapy with daratumumab (DARA) IV after total body irradiation (TBI)-based myeloablative conditioning and allogeneic hematopoietic cell transplantation (HCT) for children, adolescents, and young adults (CAYA) with high-risk T-cell acute lymphoblastic leukemia (T-ALL) or T-cell lymphoblastic lymphoma (T-LLy).
Although non-small cell lung cancer (NSCLC) patients with anaplastic lymphoma kinase (ALK), c-ros oncogene 1(ROS1), and ret proto-oncogene (RET) gene fusions initially respond well to tyrosine kinase inhibitor (TKI) therapies, acquired resistance is inevitable. In many of these cases, increased activation of the erythroblastic leukemia viral oncogene homologue (ERBB) or cMet pathways appears to be...
This is a first-in-human to learn more about the investigational drug of NX-1607 in patients with advanced malignancies.
Examine the acute effects of an acute bout of exercise on Cancer Related Fatigue (CRF)
This ComboMATCH patient screening trial. The study will identify patients with certain gene changes or mutations for treatment using a combination of targeted therapy.
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in the laboratory may help researchers develop tests for the early detection of cancers.
This study will test if one dose of psilocybin, given with talk therapy, can safely help people with advanced cancer feel less anxious, less depressed, and improve quality of life. We will compare it to a placebo (inactive medicine) called niacin given with the same kind of talk therapy.