Find a Research Study

AUD is one of the most common substance use problems in the world. It is a medical condition where someone has trouble stopping or controlling their drinking, even when it causes problems at home, work, school, or with their health. Right now, there are only a few medications to treat AUD, so more research is needed to find safe and effective options. If you join the study, your first visit will take about 2.5 to 3 hours. During this visit, you will have a physical exam and a heart test, give blood and urine samples, take a breath test for alcohol, and fill out surveys. If you qualify, you will be randomly placed into one of three groups, like flipping a coin. You will get either 60 mg of Apremilast, 90 mg of Apremilast, or a placebo, which is a pill that looks the same but has no active medicine. After joining a group, you will continue with similar tests and questionnaires during the study. The study lasts up to 10 weeks. You will visit the clinic at the CU Anschutz campus about 7 times, with maybe a few extra visits. Two weeks after your last visit, you will have a follow-up phone call. There is no cost to join the study. You can earn up to $605 for completing all study visits.

Who can Participate

You may be able to join the study if you are 21 or older, drink alcohol regularly, have AUD, and want help to cut down or stop drinking.

Study ID

More information available at ClinicalTrials.gov: NCT07325266