BONE-PAC
Aim 1: To determine if there is an association between certain gait patterns and activity specific spasticity severity with tibial bone architecture/strength. Aim 2: To compare the physiological response to an acute resistance-based bout of physical activity between adolescents with and without CP to generate an effect size for future sample size calculations. Aim 3: To determine the safety and feasibility of executing dynamic physical performance assessments.
Why this Research Matters
Participants in this study will be asked to complete 2 study visits. Participants will answer a series of questionnaires about your physical and dietary habits. You will have body composition and bone density measured. Bone architecture will also be measured. You will also complete balance, gait and physical performance testing in the Center for Movement and Gait analysis at Children's Hospital Colorado.
Who can Participate
-13-19 years old -No physical activity participation restrictions Study group (CP) o Diagnosis of spastic cerebral palsy o Hemiplegic spasticity distribution (i.e., spasticity on one side of the body) o Spasticity in a muscle that crosses the ankle (Gastrocnemius, Soleus, Tibialis Anterior, Tibialis Posterior, Peroneal Longus) o Gross motor function classification scale (GMFCS) I, or II o Able to ambulate for at least 1 hour Control Group (TD) -Typically developing (no diagnosis of a developmental disorder)
Study ID
Protocol Number: 25-2429
Meet the Team
Principal Investigator