REST: Improving Sleep Health and Timing to Support Health in Teens
The purpose of this study is to learn if improving sleep habits and sleep timing can help improve blood sugar and heart health in teens who do not get enough sleep.
Why this Research Matters
Many high school students do not get the recommended amount of sleep. Poor sleep may increase the risk of obesity, type 2 diabetes, and heart disease. Learning more about the relationship between sleep and health may help researchers find new ways to improve overall health and well-being in teens.
What to Expect
We are testing whether small changes to a sleep routine can improve sleep quality. If you join this study, you will have six study visits. The first visit is a video consent visit, where we will explain the study in more detail and confirm you still want to participate. The second visit is an in-person screening visit. During this visit, we will do a physical exam, take measurements of your body, and ask you to fill out surveys to see if you are eligible to join the study. We will also ask you to complete two sleep assessments. One involves wearing a watch while you sleep at home. The other is an overnight sleep study device you will wear at home for one night. If you qualify for the study, you will help us by testing two different sleep plans. Each plan will last for two weeks, and you will have a one-month break between the two plans. One sleep plan involves you following your normal sleep schedule. In the other plan, you will go to bed earlier, take melatonin, and wear light glasses in the morning. During both sleep plans, you will wear devices that monitor your sleep, physical activity, and blood sugar. After completing each sleep plan, you will have an overnight visit with the study team. During these visits, you will fill out surveys and provide saliva and urine samples. We will also use a needle to collect blood samples to see how your body responds to food. Meals will be provided during the overnight visits.
Study Duration
If you join this study, you will be in the study for about 3 months. All visits will take place at Children’s Hospital Colorado.
Who can Participate
You may be able to join this study if you:
- Are a high school student
- Are between 14 and 19 years old
- Have a BMI above the 85th percentile
- Speak English
- Have been diagnosed with a sleep disorder (such as insomnia or sleep apnea)
- Have a mental or physical health condition that affects sleep
- Take medications that affect sleep (such as stimulants, sleep aids, or GLP-1 medications)
- Are enrolled in a non-traditional high school
Study ID
Protocol Number: 25-1531
More information available at ClinicalTrials.gov: NCT07618117
Compensation Information
Meet the Team
Principal Investigator