By December 2030, implement and evaluate in up to 90 IBD care sites the key components of the IBD Learning Health System that enables continuous collection of health information to improve quality of care in IBD.
The IBD Qorus Program focuses on developing a patient and provider learning health system that will support the testing of strategies to improve care for adult IBD patients. The key components of an IBD Learning Health System that are within the scope of this program include: 1) use of a health information technology (HIT) solution to support both patients and providers at point of care, 2) testing strategies to improve the delivery of care in diverse IBD care centers across the U.S., and 3) developing and implementing care pathways to reduce variation in care and to address unmet clinical needs in the care of IBD patients.A treatment strategy that has shown promise in resolving symptoms and controlling underlying inflammation in clinical trials is “treat-to-target” (TTT). TTT involves establishing specific treatment targets – such as resolving inflammation in the mucosa of the gut known as mucosal healing – and closely monitoring progress toward achieving that target. Monitoring involves regular clinical assessments, laboratory tests, and endoscopy or imaging. If the target is not met, the TTT approach recommends a treatment adjustment, which may involve iteratively increasing the medication dose, switching to a different medication, and/or adding a new medication, until the target is achieved. Controlled clinical studies have found that this proactive approach can significantly improve remission rates, reduce disease progression, and prevent long-term complications.
All adult patients with inflammatory bowel disease that are starting, switching, or optimizing their treatment plan.
Protocol Number: 25-1198
Principal Investigator