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Phase 1b, Multicenter, Open-label, Dose Escalation and Dose Expansion Study of RMC-6291 in Combination with RMC-6236 in Participants with Advanced KRASG12C-Mutated Solid Tumors

This is a first-in-human study to learn more about the study drugs called RMS-6291 and RMC-6236.


Why this Research Matters

This is an open-label, multicenter, Phase 1b study of RMC-6291 in combination with RMC-6236 in participants with advanced KRAS G12C-mutated solid tumors. The study has two parts: Part 1 - Dose-Escalation and Part 2 Dose-Expansion.


Who can Participate

Adult

Detailed eligibility criteria is available on ClinicalTrials.gov. These requirements will be discussed with your doctor and/or study representative. Visit ClinicalTrials.gov to learn more about this study.


Study ID

Protocol Number: 24-0554
More information available at ClinicalTrials.gov: NCT06128551

Meet the Team

Image of Principal Investigator

Tejas Patil, MD

Principal Investigator


Categories

Locations