We will investigate the association between transfusion of fibrinogen-containing blood products and multi-organ dysfunction resulting from endotheliopathy of trauma (EOT). Fibrinogen is frequently acutely decreased in critically ill trauma patients. Early
Blood draws will be completed at baseline, 6-24 hours after arrival, and then daily through study day 7 to evaluate fibrinogen levels and response to trauma.
Acute traumatic injury Acute traumatic injury, over 18, admitted to STICU at UCH within 24 hours of hospital admission
Protocol Number: 23-0581
Principal Investigator