The study could help us develop new therapies to treat diabetic neuropathy (DN). This would have a huge impact on the well-being of DN patients and on society. What you will do: 1st visit: You will talk about your health history, fill out questionnaires, have a neurological and physical exam, and give blood for lab tests. 2nd visit: You will talk about your diet, fill out questionnaires, have neuropathy assessments, have 3 mm skin biopsies taken from your leg, and give blood for lab tests. The study could lead to the development of therapies for Diabetic Neuropathy (DN), which would have a critical impact on the wellbeing of DN patients and on society.

Who can Participate

-Age 18 - 65 years old. -Able to complete 2 research visits on the CU Anschutz Health Campus -Diagnosed with Type 2 Diabetes (with or without neuropathy) or are healthy Controls: You may be eligible for this study if you: -Are 18 to 65 years old -Can come to the UCHealth University of Colorado Anschutz for 2 research visits -Are in good general health -Have not been diagnosed with type 2 diabetes -Have not been diagnosed with peripheral neuropathy Type 2 Diabetes: You may be eligible for this study if you: -Are 18 to 65 years old -Can come to the UCHealth University of Colorado Anschutz for 2 research visits -Have been diagnosed with type 2 diabetes (with or without neuropathy)

Study ID