EnVision CF Multicenter Study of Glucose Tolerance in Cystic Fibrosis

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The purpose of this study is to find out what the normal levels of insulin and blood sugar are in children and adults with Cystic Fibrosis. In this study participants will undergo a 3 hour Oral Glucose Tolderance Test, OGTT, and have the option to wear a Continuous Glucose Monitor, CGM, and get a DXA scan.


Child to Adult


Inclusion Criteria: Age >/= 6 years Diagnosis of cystic fibrosis CF patients regularly attending the CF centers Clinically stable in previous 3wks: absence of major clinical events including pulmonary exacerbations, no change in their habitual treatment regimen including introduction of antibiotics or steroids in the past 3 weeks Exclusion Criteria: Diagnosis of type 1 diabetes, type 2 diabetes, or MODY Organ transplantation new diagnosis of CFRD in the past 6 months antidiabetic treatment in past 6 mos (insulin or oral hypoglycemic agents) -patients with previous CFRD diagnosis, but not currently taking insulin/glucose-lowering medications for at least 6 months should be included pulmonary exacerbation associated with systemic steroid requirement in the last 6 months on CFTR corrector less than 6 months prior to enrollment

Type of Study



Childrens Hospital Colorado
University of Colorado Hospital

Principal Investigator
Photograph of Christine Chan,  MD

Christine Chan, MD

Study ID

Protocol Number: 19-0422

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