Evaluation and Demonstration of Investigational MRI Software and Hardware

Primary Objective

Test new MRI scanner sequences in diverse patient and healthy volunteer population

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Description

The goal of this project is to develop advanced MRI pulse sequences and use newly acquired hardware to evaluate the potential to obtain faster or better quality images in the context of pediatric imaging and/or adult congenital disease subjects. The long-term goal is to improve the ability of MRI to diagnose cardiovascular, musculoskeletal, and other diseases. Techniques developed and/or hardware used during this project will be aimed at improving the patient experience (scan time) and/or quality of imaging (increased resolution, signal to noise, etc.).

Details
Age
All Ages
Eligibility
Inclusion and Exclusion Criteria: Subjects must meet all the following inclusion criteria to be enrolled in the study: Patients: All subjects: Male and female ages 0-80 which includes the following: Pregnant Females: Ages 18 and older will be included if in 2nd or 3rd trimester o Subject willingness and ability to comprehend and provide informed consent o Scheduled for routine MRI care at CHCO o Pass routine MR safety screening Children: Ages 0-17 o Subject or subject guardian willingness and ability to comprehend and provide informed assent and/or consent o Scheduled for routine MRI care at CHCO o Pass the Routine MR safety screening Healthy Volunteers: o Healthy male and females ages 0-80 without cardiovascular disease o Undergoing routine cardiovascular MR imaging for entities other than structural heart disease o Subject or subject guardian willingness and ability to comprehend and provide informed consent o Pass routine MR safety screening All Subjects will be excluded if any of the following exclusion criteria apply: Subject or subject guardians who are unwilling or unable to give written informed consent Pregnant females will be excluded if in 1st trimester If the SOC MRI exam plus the research add-on exam is expected to exceed 75 minutes in total, the individual will not be recruited Contraindication to MRI (a determined and documented by MRI screening intake form) o claustrophobia o cardiac pacemaker o non-MRI compatible implants o dyspnea precluding the ability to follow breath-hold instructions
Locations

Childrens Hospital Colorado

Principal Investigator
Photograph of Alex Barker

Alex Barker

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