Back to Results

SANDIA: Supplementing L-citrulline to overweight late Asthma oNset phenotypes to increase airway L-arginine/ADMA ratio and Improve Asthma control

Study category: Respiratory

Is this Study for You?

Let's Get Started!

Description

This is a proof-of-concept, randomized, double blinded, placebo controlled study to determine if adding on L-citrulline to controller therapy in obese late onset asthmatics: a) improves asthma control, and b) increases FeNO levels. Secondary research questions are to determine if L-citrulline supplementation can: a) increase plasma L-Arginine/ADMA ratio, b) improve lung function (FEV1), and c) reduce bronchial hyperresponsiveness (methacholine PC20).

Details
Age

Adult

Eligibility

1. Asthma 2. BMI >/= 30 3. Not currently smoking 4. Prescribed asthma medication

NA

Type of Study

Treatment

Locations

Outpatient CTRC
University of Colorado Hospital

Principal Investigator
Fernando Holguin,  MD

Fernando Holguin, MD

Study ID

Protocol Number: 19-0219

More information available at ClinicalTrials.gov: NCT03885245

Categories

Is this Study for You?

Let's Get Started!

Not finding the right Study for you? Join ResearchMatch, a nation-wide registry connecting volunteers and researchers