SANDIA: Supplementing L-citrulline to overweight late Asthma oNset phenotypes to increase airway L-arginine/ADMA ratio and Improve Asthma control
This is a proof-of-concept, randomized, double blinded, placebo controlled study to determine if adding on L-citrulline to controller therapy in obese late onset asthmatics: a) improves asthma control, and b) increases FeNO levels. Secondary research questions are to determine if L-citrulline supplementation can: a) increase plasma L-Arginine/ADMA ratio, b) improve lung function (FEV1), and c) reduce bronchial hyperresponsiveness (methacholine PC20).
MoreAdult
1. Asthma 2. BMI >/= 30 3. Not currently smoking 4. Prescribed asthma medication
NA
Treatment
Outpatient CTRC
University of Colorado Hospital
Fernando Holguin, MD
Protocol Number: 19-0219
More information available at ClinicalTrials.gov: NCT03885245
Is this Study for You?
Not finding the right Study for you? Join ResearchMatch, a nation-wide registry connecting volunteers and researchers