Cannabidiol for Individuals at Risk for Alzheimer's Disease: A Randomized Placebo Controlled Trial

Primary Objective

To compare effects of full spectrum hemp-derived CBD (FS-CBD, 200mg), to CBD alone (200mg CBD), and placebo on the primary outcome measures (CDR-SB score, plasma N-p-tau181, plasma Aβ42/Aβ40 ratio, Nfl) and secondary outcome measures (pain, sleep quantity/quality, anxiety) over the course of a 24-week RCT

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1. Must be between the ages of 55 - 85 and provide valid informed consent. 2. Participant must receive a diagnosis of Mild Cognitive Impairment after a careful cognitive and functional evaluation by a clinician.

Type of Study



Outpatient CTRC
University of Colorado Hospital

Principal Investigator
Photograph of Kent Hutchison,  PhD

Kent Hutchison, PhD

Study ID

Protocol Number: 23-0619

More information available at NCT05822362

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