IMVT-1401-3201: A Phase 3, Multi-center, Randomized, Quadruple-masked, Placebo-controlled Study of Batoclimab for the Treatment of Participants with Active Thyroid Eye Disease (TED)

Primary Objective

To evaluate the efficacy of batoclimab 680 mg subcutaneously (SC) once a week (QW) for 12 weeks followed by 340 mg SC QW for 12 weeks versus placebo on proptosis responder rate at Week 24

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Description

Study IMVT-1401-3201 is a Phase 3, multi-center, randomized, quadruple‑masked (Sponsor, Investigator, assessor, and participant), placebo‑controlled study was designed to assess the efficacy and safety of batoclimab in adult participants with active, moderate to severe TED. The study duration for an individual participant may be up to 32 weeks.

Details
Age
Adult
Eligibility
The study population will consist of participants 18 years or older who have active, moderate to severe TED.
Locations

University of Colorado Hospital

Principal Investigator
Photograph of Prem Subramanian

Prem Subramanian

Study ID

Protocol Number: 22-1591

More information available at ClinicalTrials.gov: NCT05517421

Categories

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