In Expansion Arm, participants must have one of the following genotypic mutations: RTK mutation, amplification or re-arrangement; KRAS-G12, BRAF Class 3 or NF1 LOF mutation.
I - Research Studies that focus on the safety of a drug. The goal is to determine the drug's most frequent and serious adverse events and, often, how the drug is broken down and excreted by the body. These studies usually involve a small number of participants.
University of Colorado Hospital
Protocol Number: 18-1150
More information available at ClinicalTrials.gov: NCT03634982
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