Intermuscular adipose tissue (IMAT) - protagonist in sarcopenia and insulin resistance in humans
Primary Objective
This study plans to learn more about how different adipose tissues are related to diabetes and muscle mass and strength, as well as how to non-invasively track liver disease in those undergoing elective abdominal surgeries.
Description
Participants will be asked to complete a screening visit prior to their procedure which will include a fasted OGTT, DEXA scan, muscle strength testing, and MRI of the abdomen and thigh. During surgery, the research team will perform a muscle biopsy of the vastus lateralis, and the surgeon will take biopsies of the liver, abdominal muscle, and abdominal fat.
Details
Locations
Outpatient CTRC
University of Colorado Hospital
Principal Investigator
Bryan Bergman
Study ID
Protocol Number: 18-0582
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