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Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally Advanced Head and Neck Cancer with a Contraindication to Cisplatin

Study category: Cancer

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Details
Age

Adult

Phase

II/III - A combination of phases: (2) Research Studies that gather preliminary data on whether a drug works in people who have a certain condition/disease (that is, the drug's effectiveness). For example, participants receiving the drug may be compared to similar participants receiving a different treatment, usually an inactive substance (called a placebo) or a different drug. Safety continues to be evaluated, and short-term adverse events are studied. and (3) Research Studies that gather more information about a drug's safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. These studies typically involve more participants.

Type of Study

Treatment

Locations

Greeley Campus
Harmony Campus
Lone Tree Medical Center
Long's Peak Hospital
Longs Peak Hospital
Medical Center of the Rockies
Memorial Hospital Central
Poudre Valley Hospital
University of Colorado Hospital

Principal Investigator
Sana Karam,  MD, PhD

Sana Karam, MD, PhD

Study ID

Protocol Number: 18-0286

ClinicalTrials.gov: NCT03258554

Categories

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