DHEA Augmentation of Musculoskeletal Adaptations to Exercise in Older Women

This Study is
No Longer Enrolling

Description

If you join the study, you will be placed by chance into one of two research groups: 1) exercise and a study pill or 2) no exercise and a study pill. The study pill could be DHEA (50 mg/day) or a placebo. A placebo is a pill that looks like medicine but is not real. DHEA is a naturally occurring hormone that declines with age. In postmenopausal women, nearly all estrogen and most testosterone comes from DHEA. DHEA is considered a food supplement.

Details
Age

Adult

Eligibility

Women, 60-85 years of age; not using sex hormone replacement (like estrogen); not exercising regularly; have low bone mass (osteopenia); willing to attend exercise sessions 3 days per week in the Exercise Research Lab on the Anschutz Medical Campus; planning to remain in the greater Denver area for the next 12 months.

no history of hormone sensitive cancer (for example, breast cancer); nonsmoking

Type of Study

Outcomes Research

Locations

Brain Imaging Center - BIC
Outpatient CTRC
University of Colorado Hospital

Study ID

Protocol Number: 16-2427

More information available at ClinicalTrials.gov: NCT03227458

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