Randomized Trial of Sedative Choice for Intubation ("RSI") Trial
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Description
Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, but the optimal sedative medication for intubation of critically ill adults remains unknown. Ketamine and etomidate are the two most commonly used sedatives during intubation of critically ill adults. Data from a randomized clinical trial are urgently needed to determine the effect of ketamine versus etomidate on cardiovascular complications and clinical outcomes of emergency tracheal intubation.
Details
Locations
University of Colorado Hospital
Principal Investigator
![Photograph of Adit Ginde](https://som.ucdenver.edu/FIMS/Content/faculty/3529/CU-Doctors-3529.jpg)
Adit Ginde
Study ID
Protocol Number: 22-2304
More information available at ClinicalTrials.gov: NCT05277896
Categories
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