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Therapeutic modulation of the intestinal creatine kinase system in inflammatory bowel disease (IBD)

Primary Objective

Specific Aim 1: Determine whether creatine supplementation induces improvement in the endoscopic assessment of mucosal inflammation in ulcerative colitis (UC). Specific Aim 2: Evaluate the feasibility of the current study protocol. Specific Aim 3: Assess the impact of creatine supplementation on intestinal epithelial barrier function and the intestinal microbiome.

Study category: Digestive Health

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Details
Age

Adult

Phase

Pilot - A pilot Study is used to obtain information, and work out the logistics and management, deemed necessary for further Research Studies.

Type of Study

Treatment

Scope

Local

Location

University of Colorado Hospital

Principal Investigator
Mark Gerich,  MD

Mark Gerich, MD

Study ID

Protocol Number: 13-3054

ClinicalTrials.gov: NCT02463305

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