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Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex
Primary Objective
This study will define the relationship of cardiac, vascular function and skeletal muscle blood flow (individually and together) to cardiovascular exercise capacity in in men and women with and without type 2 diabetes (T2DM). Identification of differences in the effects of exercise training on the integrated cardiovascular system and metabolism in men and women with and without T2DM will reveal specific adaptive responses to exercise. This study will evaluate & compare exercise function in a total of 60 subjects from the Denver area (30 people with T2DM and 30 overweight control subjects).
Details
Age
Adult
Eligibility
Men and women ages 30-55 with type 2 diabetes OR men and women ages 30-55 without type 2 diabetes.
Phase
Not Applicable - Describes studies without FDA-defined phases, including studies of devices or behavioral interventions.
Type of Study
Outcomes Research
Scope
Local
Location
University of Colorado Hospital
Principal Investigator
Jane Reusch, MD
Study ID
Protocol Number: 17-0356
ClinicalTrials.gov: NCT03419195
Categories
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