Detection of Colorectal Cancer or Advanced Neoplasia by Stool DNA in Lynch Syndrome: CORAL Study
Primary Objective
To determine the sensitivity and specificity of the mt-sDNA 2.0 test, for colorectal neoplasia in patients with Lynch Syndrome
Description
The purpose of this research is to determine a new approach for non-invasive screening and early detection of Colorectal Cancer or Advanced Neoplasia in patients with Lynch syndrome. Participation in this study includes one time stool collection and an optional blood colletion.
Details
Age
Adult
Eligibility
Patients at least 18 years of age
Individuals diagnosed with Lynch syndrome (mutation in MLH1, MSH2, MSH6, PMS2, EPCAM) or CRC with suspected Lynch syndrome or individuals diagnosed with early onset CRC (<55 yo)
Colonoscopy/Flex Sig scheduled +/- 90 days from sample collection
Patient has agreed to participate and has signed the study consent form
Locations
University of Colorado Hospital
Principal Investigator
Swati Patel
Study ID
Protocol Number: 24-0824
Categories
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