Phase 1b, Multicenter, Open-label, Dose Escalation and Dose Expansion Study of RMC-6291 in Combination with RMC-6236 in Participants with Advanced KRASG12C-Mutated Solid Tumors

Primary Objective

This is a first-in-human study to learn more about the study drugs called RMS-6291 and RMC-6236.

Is This Study For You?

Let's Get Started!

Description

This is an open-label, multicenter, Phase 1b study of RMC-6291 in combination with RMC-6236 in participants with advanced KRAS G12C-mutated solid tumors. The study has two parts: Part 1 - Dose-Escalation and Part 2 Dose-Expansion.

Details
Age
Adult
Eligibility
Detailed eligibility criteria is available on ClinicalTrials.gov. These requirements will be discussed with your doctor and/or study representative. Visit ClinicalTrials.gov to learn more about this study.
Locations

CTRC Inpatient
Outpatient CTRC
University of Colorado Hospital

Principal Investigator
Photograph of Tejas Patil

Tejas Patil

Study ID

Protocol Number: 24-0554

More information available at ClinicalTrials.gov: NCT06128551

Categories

Is this Study for You?

Let's Get Started!

Not finding the right Study for you? Join ResearchMatch, a nation-wide registry connecting volunteers and researchers