Effect of weight loss on intermuscular adipose tissue (IMAT) signaling
![](https://researchstudies.cuanschutz.edu/Content/images/study-category-images/nutrition-5.jpg)
Description
Following screening visits involving body composition measures, blood testing, strength testing, and a thigh muscle biopsy, participants will go through a 12-week dietary intervention for weight loss. After 12 weeks, this will be followed by the same testing and biopsies that were completed before the intervention.
Details
18 to 70 years
Inclusion Criteria: Generally healthy men and women aged 18-70 BMI between 30-40 Less than 1 hour of exercise per week Women: may be pre or post menopausal Exclusion Criteria: Type 1 or Type 2 diabetes Thyroid disease History of lung disease Active use of nicotine Severe plasma lipid disorders Taking hormone replacement drugs, blood thinners, or thiazoladinediones Women: Currently going through menopause or peri-menopause Pregnant or breastfeeding History of Polycystic Ovary Syndrome
compensation provided
Locations
Brain Imaging Center (BIC) - Scan Read
CTRC Inpatient
Outpatient CTRC
Principal Investigator
![Photograph of Bryan Bergman](https://researchstudies.cuanschutz.edu/Content/images/investigators/17923-prininv.jpg)
Bryan Bergman
Study ID
Protocol Number: 23-0545
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