Evaluation of Clinical Effectiveness, Cost, and Implementation Factors to Optimize Scalability of Treatment for Co-occurring SUD and PTSD Among Teens

Primary Objective

Real world comparison of Encompass and Risk Reduction Through Family Therapy (RRFT)

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This study is designed as a real-world evaluation of two integrated treatments for substance use and trauma, Risk Reduction Through Family Therapy (RRFT) or Encompass Treatment for adolescents with co-occurring Substance Use Disorder (SUD) and symptoms of Post-Traumatic Stress Disorder (PTSD). Eligible participants will be randomly assigned to RRFT or Encompass (TAU) and will complete four research visits over the course of one year.


Child to Adult


Inclusion Criteria: 1) Aged 13-18 years; 2) Experienced lifetime DSM-V PTSD Criteria A-defined potentially traumatic event, such as interpersonal violence, with memory of incident(s), such as child sexual abuse (forced or unwanted vaginal or anal penetration by an object, finger, or penis; oral sex; touching of the respondent's breasts or genitalia; or respondents touching of another persons genitalia); child physical abuse (nonaccidental physical injury to the child or any action that results in a physical impairment of the child), witnessed domestic violence (exposure to conduct by a household member against another household member that involves attempted or completed assault or murder); witnessed community violence; dating violence; as well as disasters, accidents, etc.; 3) Five or more current DSM-V PTSD symptoms; 4) Substance use, defined as alcohol or non-tobacco drug use, in the past 90 days prior to study screening per self-report; 5) English-speaking. Exclusion Criteria: 1) Presence of Pervasive Developmental Disability or Moderate/Severe Mental Retardation or other cognitive limitation that would preclude meaningful engagement in RRFT or cognitive-behavioral therapy; 2) Actively suicidal/homicidal; 3) Active psychosis.

Type of Study



Department Specific Free Standing Clinic

Principal Investigator
Photograph of Paula Riggs,  MD

Paula Riggs, MD

Study ID

Protocol Number: 21-3736

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