A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Phase 3 Study to Investigate the Efficacy and Safety of FInerenone, in Addition to Standard of Care, on the Progression of Kidney Disease in Patients with Non-Diabetic Chronic Kidney Disease

Primary Objective

Finerenone vs. Placebo in addition to Standard of Care on the Progression of Kidney Disease in non-Diabetic Patients

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Description

Trial to examine: -the impact of Finerenone vs. Placebo in delaying the progression of kidney disease. -the safety of Finerenone vs. Placebo in addition to standard of care treatment -quality of life measures via survey This trial will include 1580 participants worldwide. Study duration is approximately 2.5-4 years with an estimated 18 visits. Procedures include blood and urine collection, vital signs, EKG, questionnaires, and phone calls in between visits. The study offers an option for some visits to occur remotely. Compensation for participation is provided.

Details
Age
Adult
Eligibility
-Age 18 years and older -Chronic kidney disease -Proteinuria -Non-diabetic Exclusion criteria: -Polycystic kidney disease -Organ transplant recipient -Uncontrolled blood pressure Further eligibility will be assessed by study coordinator.
Locations

Renal Research Center

Principal Investigator
Photograph of Jessica Kendrick

Jessica Kendrick

Study ID

Protocol Number: 21-4551

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